Somatic Mutations and Autoimmunity
Round 1
Reviewer 1 Report
This review Alriyami and Polychronakos focuses on somatic mutation as novel risk factor that contribute to development of autoimmune diseases. The topic is quite interesting, as understanding the role of somatic mutations in autoimmunity contribute to unveil novel aspect in the pathogenesis of autoimmune conditions.
The review is timely and well-written. The figure is helpful. I have no specific comments for improvement. May be the authors want to report in the manuscript a table describing the main and novel technical approaches to detect mutations in autoimmunity.
Author Response
We thank the reviewer for reviewing our paper.
We have inserted the suggested table describing the main technical approaches used to detect somatic mutations in autoimmunity.
Reviewer 2 Report
This is a very timing and interesting review based on the novel concept of the somatic mutation contribution in autoimmune diseases. Besides, it is well conceived and well written.
Author Response
We thank the reviewer for reviewing our paper.
