Risk Reduction of Intrahepatic Abscess After Locoregional Therapy for Liver Cancer in Patients with Prior Hepatobiliary Intervention
Abstract
:1. Introduction
2. Risk of Liver Abscess in Patients Without Prior Hepatobiliary Intervention
3. Risk of Liver Abscess in Patients with Prior Hepatobiliary Intervention
Treatment Modality | Timing: Antibiotics (Dosing) | Bowel Preparation | Abscess Rate |
---|---|---|---|
Radiofrequency Ablation [6] | D0: Ceftriaxone (2 g) + Metronidazole (1 g) D0 to D4: Piperacillin-tazobactam (4 g × 2) | No | 4/13 (31%) |
Microwave Ablation (Group A) [1] | D0: Cefazedone (2 g × 4) + Amoxicillin-flucloxacillin sodium (2 g × 2) + Levofloxacin (0.5 g) | No | 6/10 (60%) |
Microwave Ablation (Group B) [1] | D(−1): Metronidazole (0.4 g × 3) + Gentamicin sulphate (8 WU × 3) D0 to D4: Imipenem cilastatin sodium (1 g × 2) + Linezolid (0.6 g × 2) | Yes | 0/10 (0%) |
Transarterial Chemoembolization [30] | D(−1) to D1: Tazobactam/piperacillin (3.375 g × 4) | Yes | 0/4 (0%) |
Yttrium-90 Radioembolization [24] | D(−2) to D13: Levofloxacin + Metronidazole | Yes | 0/16 (0%) |
4. Prophylactic Regimens
5. Diagnosis and Management of Liver Abscesses
6. Discussion
7. Conclusions
Author Contributions
Funding
Data Availability Statement
Conflicts of Interest
References
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Treatment Modality | Incidence of Liver Abscess Across Studies |
---|---|
Chemoembolization | 0.2–8.8% |
Yttrium-90 Radioembolization | 6.6% |
Radiofrequency Ablation | 0.3–1.8% |
Microwave Ablation | 0.4–1.6% |
Laser-Induced Thermotherapy | 0.7% |
Radiation Therapy | 3.6% |
Surgical Resection | 3.0% |
Treatment Modality | Incidence of Liver Abscess Across Studies |
---|---|
Chemoembolization | 12.1–85.7% |
Radioembolization | 7.1% |
Radiofrequency Ablation (RFA) | 22–100% |
Microwave Ablation (MWA) | 27.2–80% |
Surgical Resection | 10.6% |
Yttrium-90 Radioembolization | 0% |
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Rudnick, P.; Feia, K.; Laeseke, P.; Herman, J.; Geschwind, J. Risk Reduction of Intrahepatic Abscess After Locoregional Therapy for Liver Cancer in Patients with Prior Hepatobiliary Intervention. Diagnostics 2025, 15, 333. https://doi.org/10.3390/diagnostics15030333
Rudnick P, Feia K, Laeseke P, Herman J, Geschwind J. Risk Reduction of Intrahepatic Abscess After Locoregional Therapy for Liver Cancer in Patients with Prior Hepatobiliary Intervention. Diagnostics. 2025; 15(3):333. https://doi.org/10.3390/diagnostics15030333
Chicago/Turabian StyleRudnick, Peter, Kaleb Feia, Paul Laeseke, Joseph Herman, and Jeff Geschwind. 2025. "Risk Reduction of Intrahepatic Abscess After Locoregional Therapy for Liver Cancer in Patients with Prior Hepatobiliary Intervention" Diagnostics 15, no. 3: 333. https://doi.org/10.3390/diagnostics15030333
APA StyleRudnick, P., Feia, K., Laeseke, P., Herman, J., & Geschwind, J. (2025). Risk Reduction of Intrahepatic Abscess After Locoregional Therapy for Liver Cancer in Patients with Prior Hepatobiliary Intervention. Diagnostics, 15(3), 333. https://doi.org/10.3390/diagnostics15030333