Effectiveness and Personalized Approaches in the Correction of Gummy Smile: A Systematic Review of Orthodontic and Surgical Treatments
Abstract
:1. Introduction
2. Materials and Methods
2.1. Protocol and Registration
2.2. Search Processing
2.3. Inclusion Criteria
2.4. PICOS
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- Population: Patients with a gummy smile, defined as an excessive gingival display (≥2–3 mm), caused by various etiologies, including maxillary hyperplasia, altered passive eruption, and hyperactivity of the upper lip muscles. This review includes studies with female patients over 17 years old and male patients over 18 years old;
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- Interventions: Orthodontic and orthodontic–surgical treatments, including the use of fixed appliances, temporary anchorage devices (TADs), mini-screws, and orthognathic surgery (e.g., Le Fort I osteotomy), as well as minimally invasive approaches like botulinum toxin injections and lip repositioning;
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- Comparators: The comparison is between different therapeutic strategies for managing gummy smile, such as orthodontic treatments alone, combined orthodontic and surgical treatments, and minimally invasive procedures;
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- Outcomes: Primary outcomes include reduction in gingival display, improvement in smile aesthetics, patient satisfaction, and treatment duration. Secondary outcomes focus on the psychological impact and quality of life improvements for patients;
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- Study Desing: This review includes randomized controlled trials (RCTs) and randomized controlled clinical trials (RCCTs) published between 1 January 1982 and 4 November 2024, excluding systematic reviews, editorials, case reports, in vitro studies, and animal studies.
2.5. Exclusion Criteria
2.6. Quality Assessment and Risk of Bias
3. Results
Author and Year | Study Type | Number of Patients | Patient Characteristics | Intervention | Outcome Measures | Follow-Up | Main Findings |
---|---|---|---|---|---|---|---|
Li Xiaobing et al. 2002 [69] | Retrospective clinical study | 20 | Patients with skeletal Class II, Class I, and gingival smile | Preoperative orthodontic treatment, followed by maxillary anterior segmental osteotomy (AMSO) for correction of maxillary protrusion and gingival smile. | Cephalometric measurements of soft and hard tissues, including changes in ANB angle, alveolar height, and anterior tooth protrusion. | Not specified |
|
Zahrani et al. 2010 [70] | Observational clinical study. | 20 | Patients with skeletal class II.
| Patients with skeletal class II.
| Reduction in the ANB angle; reduction of anterior jaw height; reduction of the protrusion of the upper anterior teeth and the A-point; aesthetic improvement of the gingival smile. | Not specified | Significant reduction in ANB angle, anterior jaw height, and protrusion of the upper anterior teeth, improving facial aesthetics and effectively correcting the gingival smile.
|
Alteneiji et al., 2018 [71] | Retrospective cohort study | 69 patients (61 females, 8 males) | Adults (mean age 24.1) diagnosed with vertical maxillary excess (VME) and bimaxillary protrusion, gummy smile, increased mandibular plane angle, protrusive lip profile, lip incompetence, Angle Class I/II malocclusion | Orthodontic treatment with extraction therapy and extra-alveolar TADs (anterior and posterior maxillary TADs in all patients, with variations in mandibular TAD placement) | Cephalometric analysis with 24 measurements (angular and linear), evaluation of hard and soft tissue changes, lip retraction, mandibular rotation, posterior facial height reduction | Immediate post-treatment measurements, no long-term follow-up reported | Combined anterior and posterior TADs provided significant vertical control and mandibular rotation, favorable anterior teeth retraction, substantial soft tissue improvements, and non-surgical alternative for managing VME |
El Namrawy et al., 2019 [72] | Prospective clinical trial | 30 | A total of 21 females and 9 males aged 18 to 29, with deep bite, excessive gingival display on smiling, Class I or Class II malocclusion | Group 1: maxillary incisor intrusion using miniscrews; Group 2: intrusion using an intrusive arch | Rate of intrusion, skeletal and dental effects, soft tissue changes, patient tolerance and pain | 6 months | Both methods effectively intruded incisors; intrusive arch caused more upper incisor proclination; similar patient discomfort; no significant molar changes. |
Dutra et al., 2020 [73] | Retrospective study | 61 | A total of 38 in BTX group (6 males, 32 females, mean age: 28.60 ± 6.09 years); 23 in surgery group (7 males, 16 females, mean age: 29.59 ± 5.72 years). Patients had Class I malocclusion with no anteroposterior skeletal discrepancies. | Group 1: Botulinum toxin application; Group 2: Orthognathic surgery (Le Fort I osteotomy) | Change in gingival exposure measured from extraoral photographs before and after treatment | 1 month after treatment | Orthognathic surgery group showed significantly greater correction of gummy smile compared to the BTX group. Both interventions were effective, but surgery provided more definitive results. |
Rizzi et al., 2022 [74] | Observational comparative study | 16 | Female patients, long face pattern, VME | Orthognathic surgery with Le Fort I (surg+L1) Maxillary impaction with skeletal anchorage (orthod+MP) | Visual Analog Scale (VAS) for aesthetic perception | Not specified | Significant aesthetic improvement in both groups, with OMS and orthodontists favoring surg+L1, laypeople favoring orthod+MP |
Borba et al., 2024 [75] | Retrospective study | A total of 26 patients (13 treated with botulinum toxin, 13 treated with orthognathic surgery) | Group 1 (BTX): 13 patients (12 females, 1 male) with a mean age of 28.06 years (SD = 6.09) and mean gingival exposure during smiling of 5.18 mm (SD = 1.51) Group 2 (Surgical): 13 patients (9 females, 4 males) with a mean age of 30.59 years (SD = 5.72) and mean gingival exposure during smiling of 5.21 mm (SD = 1.55) | Group 1: Application of 2U of botulinum toxin into the levator labii superioris and nasalis muscles Group 2: Orthodontic treatment followed by maxillary impaction surgery (LeFort I osteotomy) | Smile attractiveness assessed using pre- and post-treatment photographs, rated by orthodontists, dentists, and laypeople on a scale of 0–10. | Group 1: Post-treatment photographs taken 14 days after botulinum toxin application Group 2: Post-treatment photographs taken shortly after orthodontic appliance removal | Both groups showed significant improvement in smile attractiveness post-treatment. However, the surgical group had significantly better final outcomes in smile attractiveness than the botulinum toxin group. Orthodontists rated the final smiles more favorably than dentists and laypeople, and orthognathic surgery was more effective in providing stable, long-term results. |
Miyazawa et al., 2024 [76] | Retrospective study | 16 | Japanese females aged 17–33 with Class I or II malocclusion and a gummy smile of ≥3 mm gingival exposure | Midpalatal miniscrews and modified transpalatal arch (Level Anchorage System) for maxillary molar and incisor intrusion | Vertical movement of prosthion (maxillary incisor), maxillary and mandibular molar intrusion/extrusion, mandible autorotation | Mean 4 years, 2 months | Gummy smile significantly improved by intruding the maxillary first molars and incisors, resulting in upward movement of the occlusal plane and autorotation of the mandible. |
Manikandan M et al. 2024 [77] | Randomized controlled trial | 41 | Adult subjects (mean age 30 ± 10 years) maxillary first premolar extraction, deep bite (overbite >4 mm), maxillary incisor inclination >104°, and gingival display >3 mm |
|
| At 3 months post-intrusion assessment |
|
Yeji Lee et al. 2024 [78] | Retrospective study. | 44 | Skeletal class II; lip protrusion; no bone metabolic diseases, craniofacial disorders, facial asymmetry > 5 mm, and a history of orthognathic surgery. Mean age of patients: 32.7 years, 13 males and 31 females. | ASO: extraction of premolars and surgical repositioning of anterior maxilla and mandible to reduce labial protrusion (In 22 cases, genioplasty). | Cephalometric Variables: ANB angle; SNB angle; lip retraction. Changes in Hard and Soft Tissues. Correction of Skeletal Class and Lip Retraction. | Evaluation of the surgical repositioning stability and aesthetic outcomes (patients satisfaction). |
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4. Discussion
5. Limitations
6. Conclusions
Author Contributions
Funding
Conflicts of Interest
Abbreviations
AFH | Anterior Facial Height |
AMSO | Anterior Maxillary Segmental Osteotomy |
ANB | Angle between Point A, Nasion, and Point B |
APE | Altered Passive Eruption |
ASO | Anterior Segmental Osteotomy |
BACH | Buccal Alveolar Crest Height |
BTX | Botulinum Toxin |
CBCT | Cone-Beam Computed Tomography |
CEJ | Cementoenamel Junction |
EGD | Excessive Gingival Display |
EMG | Electromyography |
IZC | Infrazygomatic Crest |
MP | Mandibular Plane |
MPA | Mandibular Plane Angle |
OMS | Oral and Maxillofacial Surgeons |
PICOS | Population, Intervention, Comparators, Outcomes, Study Design |
PRISMA | Preferred Reporting Items for Systematic Reviews and Meta-Analyses |
RCT | Randomized Controlled Trial |
RCCT | Randomized Controlled Clinical Trial |
ROBINS | Risk Of Bias In Non-randomized Studies |
S–N | Sella–Nasion |
S–N/MP | Sella–Nasion to Maxillary Plane Angle |
TADs | Temporary Anchorage Devices |
VAS | Visual Analog Scale |
VME | Vertical Maxillary Excess |
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Database | Search Field | Results (Number of Papers Found) |
---|---|---|
PubMed | ((((gummy) OR (gingiva)) AND (smile)) OR ((excessive) AND (gingival) AND (display))) AND ((orthodontic treatment) OR (orthognathic surgery)) | 288 |
Scopus | ((((gummy) OR (gingiva)) AND (smile)) OR ((excessive) AND (gingival) AND (display))) AND ((orthodontic treatment) OR (orthognathic surgery)) | 231 |
Web of Science | ((((gummy) OR (gingiva)) AND (smile)) OR ((excessive) AND (gingival) AND (display))) AND ((orthodontic treatment) OR (orthognathic surgery)) | 141 |
Cochrane | ((((gummy) OR (gingiva)) AND (smile)) OR ((excessive) AND (gingival) AND (display))) AND ((orthodontic treatment) OR (orthognathic surgery)) | 9 |
Embase | ((((gummy) OR (gingiva)) AND (smile)) OR ((excessive) AND (gingival) AND (display))) AND ((orthodontic treatment) OR (orthognathic surgery)) | 230 |
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Inchingolo, A.D.; Inchingolo, A.M.; Viapiano, F.; Netti, A.; Ciocia, A.M.; Ferrara, I.; Mancini, A.; Palermo, A.; Inchingolo, F.; Dipalma, G. Effectiveness and Personalized Approaches in the Correction of Gummy Smile: A Systematic Review of Orthodontic and Surgical Treatments. J. Clin. Med. 2024, 13, 6843. https://doi.org/10.3390/jcm13226843
Inchingolo AD, Inchingolo AM, Viapiano F, Netti A, Ciocia AM, Ferrara I, Mancini A, Palermo A, Inchingolo F, Dipalma G. Effectiveness and Personalized Approaches in the Correction of Gummy Smile: A Systematic Review of Orthodontic and Surgical Treatments. Journal of Clinical Medicine. 2024; 13(22):6843. https://doi.org/10.3390/jcm13226843
Chicago/Turabian StyleInchingolo, Alessio Danilo, Angelo Michele Inchingolo, Fabio Viapiano, Anna Netti, Anna Maria Ciocia, Irene Ferrara, Antonio Mancini, Andrea Palermo, Francesco Inchingolo, and Gianna Dipalma. 2024. "Effectiveness and Personalized Approaches in the Correction of Gummy Smile: A Systematic Review of Orthodontic and Surgical Treatments" Journal of Clinical Medicine 13, no. 22: 6843. https://doi.org/10.3390/jcm13226843
APA StyleInchingolo, A. D., Inchingolo, A. M., Viapiano, F., Netti, A., Ciocia, A. M., Ferrara, I., Mancini, A., Palermo, A., Inchingolo, F., & Dipalma, G. (2024). Effectiveness and Personalized Approaches in the Correction of Gummy Smile: A Systematic Review of Orthodontic and Surgical Treatments. Journal of Clinical Medicine, 13(22), 6843. https://doi.org/10.3390/jcm13226843