Correction: Etelcalcetide in Patients on Hemodialysis with Severe Secondary Hyperparathyroidism. Multicenter Study in “Real Life”. J. Clin. Med. 2019, 8, 1066
Conflicts of Interest
Reference
- Russo, D.; Tripepi, R.; Malberti, F.; di Iorio, B.; Scognamiglio, B.; di Lullo, L.; Paduano, I.G.; Tripepi, G.L.; Panuccio, V.A. Etelcalcetide in Patients on Hemodialysis with Severe Secondary Hyperparathyroidism. Multicenter Study in “Real Life”. J. Clin. Med. 2019, 8, 1066. [Google Scholar] [CrossRef] [PubMed] [Green Version]
Total Group (n = 168) | Naïve Group (n = 56) | Switch Group (n = 112) | p (Naïve vs Switch) | |
---|---|---|---|---|
Age (years) | 61 ± 14 | 64 ± 14 | 59 ± 14 | 0.04 |
Male (%) | 57 | 52 | 60 | 0.32 |
Dialysis vintage (month) | 58 (IQR 32–102) | 35 (IQR 14–63) | 69 (IQR 48–120) | <0.001 |
Diabetes (%) | 25 | 31 | 22 | 0.23 |
Cardiovascular comorbidities (%) | 73 | 70 | 75 | 0.53 |
iPTH (pg/mL) | 636 (IQR 493–916) | 602 (IQR 509–800) | 664 (IQR 495–947) | 0.67 |
Serum Calcium (mEq/L) | 9.0 ± 1.0 | 9.1 ± 0.7 | 9.0 ± 1.1 | 0.60 |
Serum Phosphate (mg/dL) | 5.6 ± 1.4 | 5.5 ± 1.4 | 5.6 ± 1.4 | 0.83 |
Alkaline Phosphate (U.I./L) | 131 (IQR 83–201) | 111 (IQR 74–159) | 148 (IQR 88–221) | 0.02 |
Hb (gr/dL) | 11.1 ± 1.4 | 11.0 ± 1.2 | 11.1 ± 1.4 | 0.58 |
ESA treatment (%) | 87 | 88 | 87 | 0.97 |
Phosphate binders therapy (%) | 96 | 93 | 97 | 0.17 |
Calcium containing binders (%) | 18 | 25 | 14 | 0.09 |
Vitamin D therapy (%) | 75 | 83 | 71 | 0.09 |
Native Vitamin D therapy (%) | 5 | 4 | 6 | 0.59 |
Previous cinacalcet treatment (%) | 67 | 0 | 100 | N/A |
Total Group (n = 168) | Naïve Group (n = 56) | Switch Group (n = 112) | p (Naïve vs Switch) | |
---|---|---|---|---|
Age (years) | 61 ± 14 | 64 ± 14 | 59 ± 14 | 0.04 |
Male (%) | 57 | 52 | 60 | 0.32 |
Dialysis vintage (month) | 58 (IQR 32–102) | 35 (IQR 14–63) | 69 (IQR 48–120) | <0.001 |
Diabetes (%) | 25 | 31 | 22 | 0.23 |
Cardiovascular comorbidities (%) | 73 | 70 | 75 | 0.53 |
iPTH (pg/mL) | 636 (IQR 493–916) | 602 (IQR 509–800) | 664 (IQR 495–947) | 0.67 |
Serum Calcium (mg/dL) | 9.0 ± 1.0 | 9.1 ± 0.7 | 9.0 ± 1.1 | 0.60 |
Serum Phosphate (mg/dL) | 5.6 ± 1.4 | 5.5 ± 1.4 | 5.6 ± 1.4 | 0.83 |
Alkaline Phosphate (U.I./L) | 131 (IQR 83–201) | 111 (IQR 74–159) | 148 (IQR 88–221) | 0.02 |
Hb (gr/dL) | 11.1 ± 1.4 | 11.0 ± 1.2 | 11.1 ± 1.4 | 0.58 |
ESA treatment (%) | 87 | 88 | 87 | 0.97 |
Phosphate binders therapy (%) | 96 | 93 | 97 | 0.17 |
Calcium containing binders (%) | 18 | 25 | 14 | 0.09 |
Vitamin D therapy (%) | 75 | 83 | 71 | 0.09 |
Native Vitamin D therapy (%) | 5 | 4 | 6 | 0.59 |
Previous cinacalcet treatment (%) | 67 | 0 | 100 | N/A |
Days after Parsabiv | <7.0 mEq/L | ≥7.0 or <7.5 mEq/L | ≥7.5 or <8.3 mEq/L |
---|---|---|---|
30 | 3/168 (1.8%) | 0 | 25/168 (14.9%)) |
60 | 1/129 (0.8%) | 7/129 (5.4%) | 28/129 (21.7%) |
90 | 2/111 (1.8%) | 2/111 (1.8%) | 27/111 (24.3%) |
120 | 1/80 (1.3%) | 1/80 (1.3%) | 21/80 (26.2%) |
150 | 1/61 (1.6%) | 6/61 (9.8%) | 11/61 (18.0%) |
180 | 0 | 1/44 (2.3%) | 11/44 (25.0%) |
210 | 0 | 1/51 (2.0%) | 15/51 (29.4%) |
Days after Etelcalcetide | <7.0 mg/dL | ≥7.0 or ≤7.5 mg/dL | >7.5 or <8.3 mg/dL |
---|---|---|---|
30 | 3/168 (1.8%) | 0 | 25/168 (14.9%)) |
60 | 1/129 (0.8%) | 7/129 (5.4%) | 28/129 (21.7%) |
90 | 2/111 (1.8%) | 2/111 (1.8%) | 27/111 (24.3%) |
120 | 1/80 (1.3%) | 1/80 (1.3%) | 21/80 (26.2%) |
150 | 1/61 (1.6%) | 6/61 (9.8%) | 11/61 (18.0%) |
180 | 0 | 1/44 (2.3%) | 11/44 (25.0%) |
210 | 0 | 1/51 (2.0%) | 15/51 (29.4%) |
© 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
Share and Cite
Russo, D.; Tripepi, R.; Malberti, F.; Di Iorio, B.; Scognamiglio, B.; Di Lullo, L.; Paduano, I.G.; Tripepi, G.L.; Panuccio, V.A. Correction: Etelcalcetide in Patients on Hemodialysis with Severe Secondary Hyperparathyroidism. Multicenter Study in “Real Life”. J. Clin. Med. 2019, 8, 1066. J. Clin. Med. 2020, 9, 1224. https://doi.org/10.3390/jcm9041224
Russo D, Tripepi R, Malberti F, Di Iorio B, Scognamiglio B, Di Lullo L, Paduano IG, Tripepi GL, Panuccio VA. Correction: Etelcalcetide in Patients on Hemodialysis with Severe Secondary Hyperparathyroidism. Multicenter Study in “Real Life”. J. Clin. Med. 2019, 8, 1066. Journal of Clinical Medicine. 2020; 9(4):1224. https://doi.org/10.3390/jcm9041224
Chicago/Turabian StyleRusso, Domenico, Rocco Tripepi, Fabio Malberti, Biagio Di Iorio, Bernadette Scognamiglio, Luca Di Lullo, Immacolata Gaia Paduano, Giovanni Luigi Tripepi, and Vincenzo Antonio Panuccio. 2020. "Correction: Etelcalcetide in Patients on Hemodialysis with Severe Secondary Hyperparathyroidism. Multicenter Study in “Real Life”. J. Clin. Med. 2019, 8, 1066" Journal of Clinical Medicine 9, no. 4: 1224. https://doi.org/10.3390/jcm9041224
APA StyleRusso, D., Tripepi, R., Malberti, F., Di Iorio, B., Scognamiglio, B., Di Lullo, L., Paduano, I. G., Tripepi, G. L., & Panuccio, V. A. (2020). Correction: Etelcalcetide in Patients on Hemodialysis with Severe Secondary Hyperparathyroidism. Multicenter Study in “Real Life”. J. Clin. Med. 2019, 8, 1066. Journal of Clinical Medicine, 9(4), 1224. https://doi.org/10.3390/jcm9041224