Next Article in Journal
Advances, Challenges, and Applications of Graphene and Carbon Nanotube-Reinforced Engineering Ceramics
Previous Article in Journal
Application of Polyvinyl Alcohol–Ethylene Glycol Hydrogel Technology for Removing Animal Glue in Book Restoration Based on Fluorescent Labeling Evaluation
Previous Article in Special Issue
(Sub-)Picosecond Surface Correlations of Femtosecond Laser Excited Al-Coated Multilayers Observed by Grazing-Incidence X-ray Scattering
 
 
Search for Articles:
Title / Keyword
Author / Affiliation / Email
Journal
Article Type
 
 
Advanced Search
 
Section
Special Issue
Volume
Issue
Number
Page
 
Journals
Nanomaterials
Volume 14
Issue 23
10.3390/nano14231879
nanomaterials-logo
Submit to this Journal Review for this Journal Propose a Special Issue
► Article Menu

Article Menu

share Share announcement Help format_quote Cite question_answer Discuss in SciProfiles thumb_up
...
Endorse textsms
...
Comment
first_page
settings
Order Article Reprints
Font Type:
Arial Georgia Verdana
Font Size:
Aa Aa Aa
Line Spacing:
Column Width:
Background:
This is an early access version, the complete PDF, HTML, and XML versions will be available soon.
Review

Versatile Porphyrin Arrangements for Photodynamic Therapy—A Review

by
Arleta Glowacka-Sobotta
1,
Beata Czarczynska-Goslinska
2,
Daniel Ziental
3,
Marcin Wysocki
3,4,
Maciej Michalak
3,4,
Emre Güzel
5 and
Lukasz Sobotta
3,*
1
Chair and Department of Orthodontics and Temporomandibular Disorders, Poznan University of Medical Sciences, Bukowska 70, 60-812 Poznan, Poland
2
Chair and Department of Pharmaceutical Technology, Poznan University of Medical Sciences, Rokietnicka 3, 60-806 Poznan, Poland
3
Chair and Department of Inorganic and Analytical Chemistry, Poznan University of Medical Sciences, Rokietnicka 3, 60-806 Poznan, Poland
4
Doctoral School, Poznan University of Medical Sciences, Bukowska 70, 60-812 Poznan, Poland
5
Department of Engineering Fundamental Sciences, Sakarya University of Applied Sciences, 54050 Sakarya, Türkiye
*
Author to whom correspondence should be addressed.
Nanomaterials 2024, 14(23), 1879; https://doi.org/10.3390/nano14231879
Submission received: 1 October 2024 / Revised: 18 November 2024 / Accepted: 19 November 2024 / Published: 22 November 2024
(This article belongs to the Special Issue Laser-Matter Interaction for Nanostructuration: From Fundamentals to Optical, Electrochemical, Magnetic and Electrical Quantum Sensing)
Versions Notes

Abstract

Nanotechnology is an emerging field that involves the development of nanoscale particles, their fabrication methods, and potential applications. From nanosized inorganic particles to biopolymers, the variety of nanoparticles is unstoppably growing, offering huge opportunities for drug delivery. Various nanoformulations, such as nanoparticles, nanocomposites, and nanoemulsions, have been developed to enhance drug stability, solubility, and tissue penetration. Moreover, nanocarriers can be specifically engineered to target diseased cells or release the drug in a controllable manner, minimizing damage to surrounding healthy tissues and reducing side effects. This review focuses on the combinations between porphyrin derivatives and nanocarriers applied in photodynamic therapy (PDT). PDT has emerged as a significant advance in medicine, offering a low-invasive method for managing infections, the treatment of tumors, and various dermatoses. The therapy relies on the activation of a photosensitizer by light, which results in the generation of reactive oxygen species. Despite their favorable properties, porphyrins reveal non-specific distribution within the body. Nanotechnology has the capability to enhance the PS delivery and its activation. This review explores the potential improvements that are provided by the use of nanotechnology in the PDT field.
Keywords: PDT; PACT; porphyrin; nanotechnology; bacterial infections; chlorin e6; bacteriochlorin; isobacteriochlorin PDT; PACT; porphyrin; nanotechnology; bacterial infections; chlorin e6; bacteriochlorin; isobacteriochlorin

Share and Cite

MDPI and ACS Style

Glowacka-Sobotta, A.; Czarczynska-Goslinska, B.; Ziental, D.; Wysocki, M.; Michalak, M.; Güzel, E.; Sobotta, L. Versatile Porphyrin Arrangements for Photodynamic Therapy—A Review. Nanomaterials 2024, 14, 1879. https://doi.org/10.3390/nano14231879

AMA Style

Glowacka-Sobotta A, Czarczynska-Goslinska B, Ziental D, Wysocki M, Michalak M, Güzel E, Sobotta L. Versatile Porphyrin Arrangements for Photodynamic Therapy—A Review. Nanomaterials. 2024; 14(23):1879. https://doi.org/10.3390/nano14231879

Chicago/Turabian Style

Glowacka-Sobotta, Arleta, Beata Czarczynska-Goslinska, Daniel Ziental, Marcin Wysocki, Maciej Michalak, Emre Güzel, and Lukasz Sobotta. 2024. "Versatile Porphyrin Arrangements for Photodynamic Therapy—A Review" Nanomaterials 14, no. 23: 1879. https://doi.org/10.3390/nano14231879

APA Style

Glowacka-Sobotta, A., Czarczynska-Goslinska, B., Ziental, D., Wysocki, M., Michalak, M., Güzel, E., & Sobotta, L. (2024). Versatile Porphyrin Arrangements for Photodynamic Therapy—A Review. Nanomaterials, 14(23), 1879. https://doi.org/10.3390/nano14231879

Note that from the first issue of 2016, this journal uses article numbers instead of page numbers. See further details here.

Article Metrics

Back to TopTop