Optimizing Antioxidant and Anti-Hyaluronidase Activities of Mixed Coffea arabica, Centella asiatica, and Curcuma longa Extracts for Cosmetic Application

Round 1

Reviewer 1 Report

Comments and Suggestions for Authors

The manuscript entitled “Optimizing Antioxidant and Anti-Aging Activities of Mixed 2 Coffea arabica, Centella asiatica, and Curcuma longa Extracts 3 for Cosmetic Application” reports the antioxidant and anti-aging activity after mixing three plant extracts in optimum conditions. The manuscript is well written and structured.

 

Minor changes are proposed. Below you can find my comments:

Line 138: remove dot after the word solution

Would the authors have better results using Microwave-Assisted Extraction or Ultrasound-Assisted Extraction for the pretreatment of the plants? 

Have the authors proceeded to an LC-MS/MS analysis in order to quantify the bioactive compounds in the extracts?

 

Author Response

Dear Reviewer of Cosmetics,

Title: Optimizing Antioxidant and Anti-Aging Activities of Mixed Coffea arabica, Centella asiatica, and Curcuma longa Extracts for Cosmetic Application (Manuscript ID: cosmetics-3283434)

We greatly appreciate the valuable comments and suggestions provided by all reviewers. We have carefully read and responded each comment, responding to them point by point. The specific alterations in the manuscript in response to the reviewer comments are shown in yellow highlight for comments of reviewer 1. In addition, we have reviewed and edited the English grammar in all sections.

We hope that all of the changes have adequately addressed the reviewers’ concerns, so with these improvements, we sincerely hope our work will be accepted for publication in the Cosmetics, MDPI.

Sincerely yours,

Kanokwan Kiattisin

Department of Pharmaceutical Sciences

Faculty of Pharmacy, Chiang Mai University, Chiang Mai, Thailand

 

Author Response File: Author Response.pdf

Reviewer 2 Report

Comments and Suggestions for Authors

This study is a compounding study on the antioxidant and anti-aging effects according to the content of Coffea arabica, Centella asiatica, and Curcuma longa Extracts.

 

Regarding this study, it is judged that it is difficult to predict the antioxidant and anti-aging effects of the extracts with this test alone. The reasons are as follows.

1. Variables such as the origin and cultivation environment of natural products

2. A stepwise regression analysis should be conducted for the indicator components or effective components of natural products.

3. Basis for tests representing antioxidants such as DPPH, etc., and basis for tests representing anti-aging

Without the contents of these parts, it is judged that it is difficult to apply the antioxidant and anti-aging effects claimed by this study to cosmetics.

Comments on the Quality of English Language

I don't think there is a problem with your English level.

Author Response

Dear Reviewer of Cosmetics,

Title: Optimizing Antioxidant and Anti-Aging Activities of Mixed Coffea arabica, Centella asiatica, and Curcuma longa Extracts for Cosmetic Application (Manuscript ID: cosmetics-3283434)

We greatly appreciate the valuable comments and suggestions provided by all reviewers. We have carefully read and responded each comment, responding to them point by point. The specific alterations in the manuscript in response to the reviewer comments are shown in green highlight for comments of reviewer 2. In addition, we have reviewed and edited the English grammar in all sections.

We hope that all of the changes have adequately addressed the reviewers’ concerns, so with these improvements, we sincerely hope our work will be accepted for publication in the Cosmetics, MDPI.

Sincerely yours,

Kanokwan Kiattisin

Department of Pharmaceutical Sciences

Faculty of Pharmacy, Chiang Mai University, Chiang Mai, Thailand

Author Response File: Author Response.pdf

Round 2

Reviewer 2 Report

Comments and Suggestions for Authors

This paper has been made relatively sufficiently with information on the components of plant extracts, and the logic related to efficacy has been created.

However, due to the nature of plant extracts, there are bound to be many changes in the index components depending on information on the cultivation area, climate, weather, production date, etc.

Therefore, please write by adding production information (date, region, country, etc.) for the plant extracts used in this paper.

Comments on the Quality of English Language

I can't judge the quality of English.

Author Response

Dear Reviewer of Cosmetics,

Title: Optimizing Antioxidant and Anti-hyaluronidase Activities of Mixed Coffea arabica, Centella asiatica, and Curcuma longa Extracts for Cosmetic Application (Manuscript ID: cosmetics-3283434)

Thank you, reviewer, for the opportunity to enhance the quality of our manuscript. We greatly appreciate your valuable suggestion. We have made the necessary modifications in response to your point. The specific alteration in the manuscript in response to your comment is shown in blue highlight. We hope that all of the changes have adequately addressed the reviewers’ concerns.

Sincerely yours,

Kanokwan Kiattisin

Department of Pharmaceutical Sciences

Faculty of Pharmacy, Chiang Mai University, Chiang Mai 50200 Thailand