Prevalence and Severity of Pelvic Floor Disorders during Pregnancy: Does the Trimester Make a Difference?
Abstract
:1. Introduction
2. Materials and Methods
2.1. The Pelvic Floor Questionnaire for Pregnancy and Postpartum—PFQPP
2.2. Statistical Analysis
3. Results
3.1. Sexual Domain
3.2. Bladder Domain
3.3. Bowel Domain
3.4. Prolapse Domain
3.5. Pelvic Floor Total Burden
3.6. Risk Factors
4. Discussion
Strengths and Limitations
5. Conclusions
Supplementary Materials
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Conflicts of Interest
References
- Rortveit, G.; Subak, L.L.; Thom, D.H.; Creasman, J.M.; Vittinghoff, E.; Eeden, S.K.V.D.; Brown, J.S. Urinary Incontinence, Fecal Incontinence and Pelvic Organ Prolapse in a Population-Based, Racially Diverse Cohort. Urogynecology 2010, 16, 278–283. [Google Scholar] [CrossRef] [Green Version]
- Wu, J.M.M.; Vaughan, C.P.M.; Goode, P.S.; Redden, D.T.; Burgio, K.L.; Richter, H.E.; Markland, A.D.D. Prevalence and Trends of Symptomatic Pelvic Floor Disorders in U.S. Women. Obstet. Gynecol. 2014, 123, 141–148. [Google Scholar] [CrossRef] [PubMed] [Green Version]
- Kenne, K.A.; Wendt, L.; Jackson, J.B. Prevalence of pelvic floor disorders in adult women being seen in a primary care setting and associated risk factors. Sci. Rep. 2022, 12, 9878. [Google Scholar] [CrossRef] [PubMed]
- Nygaard, I. Prevalence of Symptomatic Pelvic Floor Disorders in US Women. JAMA 2008, 300, 1311–1316. [Google Scholar] [CrossRef] [Green Version]
- Hallock, J.L.; Handa, V.L. The Epidemiology of Pelvic Floor Disorders and Childbirth. Obstet. Gynecol. Clin. N. Am. 2016, 43, 1–13. [Google Scholar] [CrossRef] [Green Version]
- Norton, P.A.; Allen-Brady, K.; Wu, J.; Egger, M.; Cannon-Albright, L. Clinical characteristics of women with familial pelvic floor disorders. Int. Urogynecology J. 2014, 26, 401–406. [Google Scholar] [CrossRef] [PubMed]
- Coyne, K.S.; Sexton, C.C.; Irwin, D.E.; Kopp, Z.S.; Kelleher, C.J.; Milsom, I. The impact of overactive bladder, incontinence and other lower urinary tract symptoms on quality of life, work productivity, sexuality and emotional well-being in men and women: Results from the EPIC study. BJU Int. 2008, 101, 1388–1395. [Google Scholar] [CrossRef]
- Palmieri, S.; De Bastiani, S.S.; Degliuomini, R.; Ruffolo, A.F.; Casiraghi, A.; Vergani, P.; Gallo, P.; Magoga, G.; Cicuti, M.; Parma, M.; et al. Prevalence and severity of pelvic floor disorders in pregnant and postpartum women. Int. J. Gynecol. Obstet. 2021, 158, 346–351. [Google Scholar] [CrossRef]
- Yohay, D.; Weintraub, A.Y.; Mauer-Perry, N.; Peri, C.; Kafri, R.; Yohay, Z.; Bashiri, A. Prevalence and trends of pelvic floor disorders in late pregnancy and after delivery in a cohort of Israeli women using the PFDI-20. Eur. J. Obstet. Gynecol. Reprod. Biol. 2016, 200, 35–39. [Google Scholar] [CrossRef]
- Braga, A.; Barba, M.; Serati, M.; Soligo, M.; Marzi, V.L.; Agrò, E.F.; Musco, S.; Caccia, G.; Castronovo, F.; Manodoro, S.; et al. Update on Italian-validated questionnaires for pelvic floor disorders. Minerva Obstet. Gynecol. 2023, 75, 62–68. [Google Scholar] [CrossRef]
- Metz, M.; Junginger, B.; Henrich, W.; Baeßler, K. Development and Validation of a Questionnaire for the Assessment of Pelvic Floor Disorders and Their Risk Factors During Pregnancy and Post Partum. Geburtshilfe Frauenheilkd. 2017, 77, 358–365. [Google Scholar] [CrossRef] [Green Version]
- Durnea, C.M.; Khashan, A.S.; Kenny, L.C.; Durnea, U.A.; Dornan, J.C.; O’Sullivan, S.M.; O’Reilly, B.A. What is to blame for postnatal pelvic floor dysfunction in primiparous women—Pre-pregnancy or intrapartum risk factors? Eur. J. Obstet. Gynecol. Reprod. Biol. 2017, 214, 36–43. [Google Scholar] [CrossRef]
- Palmieri, S.; Cola, A.; Ceccherelli, A.; Manodoro, S.; Frigerio, M.; Vergani, P. Italian validation of the German Pelvic Floor Questionnaire for pregnant and postpartum women. Eur. J. Obstet. Gynecol. Reprod. Biol. 2020, 248, 133–136. [Google Scholar] [CrossRef] [PubMed]
- Frigerio, M.; Barba, M.; Palmieri, S.; Ruffolo, A.F.; Gallo, P.; Magoga, G.; Manodoro, S.; Vergani, P. On the behalf of the Urogynecology-Pelvic Floor Working Group (GLUP) Prevalence and severity of sexual disorders in the third trimester of pregnancy. Minerva Obstet. Gynecol. 2022. [Google Scholar] [CrossRef]
- Cassis, C.; Mukhopadhyay, S.; Morris, E.; Giarenis, I. What happens to female sexual function during pregnancy? Eur. J. Obstet. Gynecol. Reprod. Biol. 2021, 258, 265–268. [Google Scholar] [CrossRef]
- Daud, S.; Zahid, A.Z.M.; Mohamad, M.; Abdullah, B.; Mohamad, N.A.N. Prevalence of sexual dysfunction in pregnancy. Trimester of pregnancy was found to have a significant association with the incidence of sexual dysfunction. Arch. Gynecol. Obstet. 2019, 300, 1279–1285. [Google Scholar] [CrossRef] [PubMed]
- Ozerdogan, N.; Sahin, B.M.; Gursoy, E.; Zeren, F. Sexual dysfunction in the third trimester of pregnancy and postpartum period: A prospective longitudinal study. J. Obstet. Gynaecol. 2022, 42, 2722–2728. [Google Scholar] [CrossRef]
- Frigerio, M.; Barba, M.; Cola, A.; Braga, A.; Celardo, A.; Munno, G.M.; Schettino, M.T.; Vagnetti, P.; De Simone, F.; Di Lucia, A.; et al. Quality of Life, Psychological Wellbeing, and Sexuality in Women with Urinary Incontinence—Where Are We Now: A Narrative Review. Medicina 2022, 58, 525. [Google Scholar] [CrossRef] [PubMed]
- Franco, E.M.; Parés, D.; Colomé, N.L.; Paredes, J.R.M.; Tardiu, L.A. Urinary incontinence during pregnancy. Is there a difference between first and third trimester? Eur. J. Obstet. Gynecol. Reprod. Biol. 2014, 182, 86–90. [Google Scholar] [CrossRef]
- Bugge, C.; Strachan, H.; Pringle, S.; Hagen, S.; Cheyne, H.; Wilson, D. Should pregnant women know their individual risk of future pelvic floor dysfunction? A qualitative study. BMC Pregnancy Childbirth 2022, 22, 161. [Google Scholar] [CrossRef]
- Dumoulin, C.; Cacciari, L.P.; Hay-Smith, E.J.C. Pelvic floor muscle training versus no treatment, or inactive control treatments, for urinary incontinence in women. Cochrane Database Syst. Rev. 2018, 2018, CD005654. [Google Scholar] [CrossRef] [PubMed]
- Hagen, S.; Glazener, C.; McClurg, D.; Macarthur, C.; Elders, A.; Herbison, P.; Logan, J. Pelvic floor muscle training for secondary prevention of pelvic organ prolapse (PREVPROL): A multicentre randomised controlled trial. Lancet 2017, 389, 393–402. [Google Scholar] [CrossRef] [PubMed] [Green Version]
- Sobhgol, S.S.; Priddis, H.; Smith, C.A.; Dahlen, H.G. The Effect of Pelvic Floor Muscle Exercise on Female Sexual Function During Pregnancy and Postpartum: A Systematic Review. Sex. Med. Rev. 2018, 7, 13–28. [Google Scholar] [CrossRef]
- Franco, M.M.; Pena, C.C.; de Freitas, L.M.; Antônio, F.I.; Lara, L.A.; Ferreira, C.H.J. Pelvic Floor Muscle Training Effect in Sexual Function in Postmenopausal Women: A Randomized Controlled Trial. J. Sex. Med. 2021, 18, 1236–1244. [Google Scholar] [CrossRef] [PubMed]
- Xu, P.; Wang, X.; Guo, P.; Zhang, W.; Mao, M.; Feng, S. The effectiveness of eHealth interventions on female pelvic floor dysfunction: A systematic review and meta-analysis. Int. Urogynecology J. 2022, 33, 3325–3354. [Google Scholar] [CrossRef]
- Lipschuetz, M.; Cohen, S.M.; Liebergall-Wischnitzer, M.; Zbedat, K.; Hochner-Celnikier, D.; Lavy, Y.; Yagel, S. Degree of bother from pelvic floor dysfunction in women one year after first delivery. Eur. J. Obstet. Gynecol. Reprod. Biol. 2015, 191, 90–94. [Google Scholar] [CrossRef]
- Jelovsek, J.E.; Barber, M.D. Women seeking treatment for advanced pelvic organ prolapse have decreased body image and quality of life. Am. J. Obstet. Gynecol. 2006, 194, 1455–1461. [Google Scholar] [CrossRef]
- Swenson, C.W.; DePorre, J.A.; Haefner, J.K.; Berger, M.B.; Fenner, D.E. Postpartum depression screening and pelvic floor symptoms among women referred to a specialty postpartum perineal clinic. Am. J. Obstet. Gynecol. 2018, 218, 335.e1–335.e6. [Google Scholar] [CrossRef]
- Hullfish, K.L.; Fenner, D.E.; Sorser, S.A.; Visger, J.; Clayton, A.; Steers, W.D. Postpartum depression, urge urinary incontinence, and overactive bladder syndrome: Is there an association? Int. Urogynecology J. 2007, 18, 1121–1126. [Google Scholar] [CrossRef]
- Vrijens, D.; Berghmans, B.; Nieman, F.; van Os, J.; Van Koeveringe, G.; Leue, C. Prevalence of anxiety and depressive symptoms and their association with pelvic floor dysfunctions—A cross sectional cohort study at a Pelvic Care Centre. Neurourol. Urodyn. 2017, 36, 1816–1823. [Google Scholar] [CrossRef]
Characteristics and Risk Factors | All Patients n = 306 | 1st Trimester n = 36 | 2nd Trimester n = 83 | 3rd Trimester n = 187 | p |
---|---|---|---|---|---|
Maternal Age | 32.6 (±4.6) | 33.4 (±4) | 32.8 (±4.7) | 32.4 (±4.8) | 0.481 |
Gestational Age | 30.5 (±20) | 10.25 (±1.7) | 19.9 (±4.4) | 34.8 (±3.6) | <0.001 b |
Pregestational weight (kg) | 62 (±12.4) | 61.1 (±11) | 61.8 (±12) | 62.8 (±12) | 0.607 |
Current weight (kg) | 70 (±12.8) | 62.2 (±11) | 67.1 (±12) | 72.7 (±12) | <0.010 a |
Age > 35 | 75 (25.9%) | 11 (31.4%) | 19 (25%) | 45 (25.1%) | 0.725 |
Familiarity with PFDs (n = 304) | 34 (11.2%) | 3 (8.6%) | 14 (16.9%) | 17 (9.1%) | 0.156 |
Smoking (n = 306) | 14 (4.6%) | 2 (5.6%) | 1 (1.2%) | 11 (5.9%) | 0.206 |
Pelvic floor contraction inability (n = 304) | 15 (4.9%) | 2 (5.6%) | 5 (6.1%) | 8 (4.3%) | 0.671 |
PFD Symptoms (n = 306) | All Trimesters | 1st Trimester (n = 36) | 2nd Trimester (n = 83) | 3rd Trimester (n = 187) | p |
---|---|---|---|---|---|
No symptoms | 120 (39.2%) | 19 (52.7%) | 35 (42.1%) | 66 (35.3%) | 0.117 |
Vesical Dysfunction | 104 (34%) | 9 (25%) | 24 (28.9%) | 71 (38%) | 0.716 |
Bowel Dysfunction | 112 (36.3%) | 11 (30.6%) | 30 (36.1%) | 71 (38%) | 0.691 |
Pelvic Support Dysfunction | 33 (10.8%) | 2 (5.6%) | 6 (7.2%) | 25 (13.4%) | 0.182 |
Sexual Dysfunction | 65 (21.2%) | 6 (16.7%) | 16 (19.3%) | 43 (23%) | 0.611 |
Sexual Inactivity | 55 (18.4%) | 3 (8.3%) | 15 (18.5%) | 37 (20%) | 0.352 |
Bother Scores | 1st Trimester | 2nd Trimester | 3rd Trimester | p |
---|---|---|---|---|
Urinary domain score | 1.15 (0.67–1.82) | 1.25 (0.62–1.87) | 1.46 (1.04–2.3) | 0.004 b |
Intestinal domain score | 1.61 (0.64–2.5) | 1.29 (0.97–2.25) | 1.61 (0.97–2.25) | 0.709 |
Pelvic domain score | 0.24 (0–0.8) | 0.38 (0–0.94) | 0.65 (0–1.29) | 0.012 b |
Sexual domain score | 1.04 (0.41–2.08) | 1.25 (0.41–2.08) | 1.25 (0.42–2.5) | 0.382 |
TOTAL score | 3.99 (2.87–5.44) | 4.41 (3.14–5.98) | 5.31 (3.62–7.12) | 0.005 b |
Significant PFQPP Items | 1st Trimester | 2nd Trimester | 3rd Trimester | p |
---|---|---|---|---|
V2 Presence of nocturia | 16 (44.4%) | 36 (43.9%) | 119 (63.6%) | 0.004 b |
V11 Use of pads due to urinary leakage | 5 (13.9%) | 13 (15.7%) | 53 (28.3%) | 0.028 b |
V14 False sensation of UTI | 3 (8.3%) | 14 (17.1%) | 48 (25.7%) | 0.037 c |
P2 Sensing prolapse of uterus or vagina at rest | 2 (5.6%) | 11 (13.3%) | 40 (21.5%) | 0.035 c |
P3 Sensing prolapse during physical effort. | 2 (5.6%) | 15 (18.1%) | 49 (26.3%) | 0.014 c |
Disclaimer/Publisher’s Note: The statements, opinions and data contained in all publications are solely those of the individual author(s) and contributor(s) and not of MDPI and/or the editor(s). MDPI and/or the editor(s) disclaim responsibility for any injury to people or property resulting from any ideas, methods, instructions or products referred to in the content. |
© 2023 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
Share and Cite
Baruch, Y.; Manodoro, S.; Barba, M.; Cola, A.; Re, I.; Frigerio, M. Prevalence and Severity of Pelvic Floor Disorders during Pregnancy: Does the Trimester Make a Difference? Healthcare 2023, 11, 1096. https://doi.org/10.3390/healthcare11081096
Baruch Y, Manodoro S, Barba M, Cola A, Re I, Frigerio M. Prevalence and Severity of Pelvic Floor Disorders during Pregnancy: Does the Trimester Make a Difference? Healthcare. 2023; 11(8):1096. https://doi.org/10.3390/healthcare11081096
Chicago/Turabian StyleBaruch, Yoav, Stefano Manodoro, Marta Barba, Alice Cola, Ilaria Re, and Matteo Frigerio. 2023. "Prevalence and Severity of Pelvic Floor Disorders during Pregnancy: Does the Trimester Make a Difference?" Healthcare 11, no. 8: 1096. https://doi.org/10.3390/healthcare11081096
APA StyleBaruch, Y., Manodoro, S., Barba, M., Cola, A., Re, I., & Frigerio, M. (2023). Prevalence and Severity of Pelvic Floor Disorders during Pregnancy: Does the Trimester Make a Difference? Healthcare, 11(8), 1096. https://doi.org/10.3390/healthcare11081096