Alzheimer’s Disease from the Amyloidogenic Theory to the Puzzling Crossroads between Vascular, Metabolic and Energetic Maladaptive Plasticity
Round 1
Reviewer 1 Report
The present article was a review for metabolomics approach to Alzheimer's disease. It was well organized.
Some figures showing schema would help to easily understand for readers.
Author Response
We appreciate and thank Reviewer 1 and as suggested, we have included figure 1 which constitutes a synopsis of the scientific proposal described in the review. Moreover, we have revised the English language to correct minor spelling issues.
Reviewer 2 Report
The authors rise an interesting hypothesis. I have 2 minor comments:
1) Genes names should be mentioned in italic letter.
2) The article should benefit from the use of 1 or more illustrative figures.
Author Response
We appreciate and thank Reviewer 2 for evaluating interesting our hypothesis. We respect the comments we have included figure 1 which constitutes a synopsis of the scientific proposal described in the review. Moreover, we have revised the English language to correct minor spelling issues, including mentioning Genes names in italic characters.