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Review

Diabetes Mellitus and Associated Complications in the Digestive Tract

by
Ioana Paunica
1,2,†,
Vlad Denis Constantin
1,3,*,†,
Dragos Serban
1,4,†,
Cristian Paius
3,
Bogdan Gaspar
1,5,
Dragos Epistatu
6,
Valentin Verlas
1,
Roxana Sfetea
7,
Liliana Florina Andronache
7,
Cristian Balalau
1,3,†,
Daniela Gabriela Bălan
1,
Alexandru Florin Motofei
1 and
Adrian Silaghi
1,3,†
1
Carol Davila University of Medicine and Pharmacy, Bucharest, Romania
2
Department of Diabetes, Nutrition and Metabolic Diseases, N.C. Paulescu National Institute, Bucharest, Romania
3
Department of General Surgery, St. Pantelimon Emergency Clinical Hospital, Bucharest, Romania
4
Department of General Surgery, Emergency University Hospital of Bucharest, Bucharest, Romania
5
Department of General Surgery, Clinical Emergency Hospital of Bucharest, Bucharest, Romania
6
Department of Radiology, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania
7
Discipline of Modern Languages, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania
*
Author to whom correspondence should be addressed.
Authors with equal contributions.
J. Mind Med. Sci. 2024, 11(2), 351-362; https://doi.org/10.22543/2392-7674.1567
Submission received: 7 June 2024 / Revised: 7 July 2024 / Accepted: 16 August 2024 / Published: 31 October 2024

Abstract

Diabetes mellitus presents an increasing prevalence and severe multisystemic complications, with notable personal, professional and social implications. Diabetes is generally known by hyperglycemia and subsequent metabolic disorders. In addition to hyperglycemia, it appears that other factors (related to anthropometric-pathophysiology and genome-based subphenotyping) are involved not only in the clinical course but also in the occurrence of diabetes complications. This review presents several diabetes-induced complications on the digestive tract (periodontal disease, xerostomia, oral infections, dental caries, taste disturbances, gastroesophageal reflux disease, gastroparesis, gastric ulcer and cancer, diabetic enteropathy, inflammatory bowel diseases, colorectal cancer, etc.), many of them with major implications and unfavorable long-term prognosis. Consequently, prompt recognition and treatment of diabetes and its complications, as well as strict follow-up education, still remain essential for the effective management of this complex metabolic disease.
Keywords: diabetes mellitus; complications; digestive tract; diagnosis; therapy; prevention diabetes mellitus; complications; digestive tract; diagnosis; therapy; prevention

Share and Cite

MDPI and ACS Style

Paunica, I.; Constantin, V.D.; Serban, D.; Paius, C.; Gaspar, B.; Epistatu, D.; Verlas, V.; Sfetea, R.; Andronache, L.F.; Balalau, C.; et al. Diabetes Mellitus and Associated Complications in the Digestive Tract. J. Mind Med. Sci. 2024, 11, 351-362. https://doi.org/10.22543/2392-7674.1567

AMA Style

Paunica I, Constantin VD, Serban D, Paius C, Gaspar B, Epistatu D, Verlas V, Sfetea R, Andronache LF, Balalau C, et al. Diabetes Mellitus and Associated Complications in the Digestive Tract. Journal of Mind and Medical Sciences. 2024; 11(2):351-362. https://doi.org/10.22543/2392-7674.1567

Chicago/Turabian Style

Paunica, Ioana, Vlad Denis Constantin, Dragos Serban, Cristian Paius, Bogdan Gaspar, Dragos Epistatu, Valentin Verlas, Roxana Sfetea, Liliana Florina Andronache, Cristian Balalau, and et al. 2024. "Diabetes Mellitus and Associated Complications in the Digestive Tract" Journal of Mind and Medical Sciences 11, no. 2: 351-362. https://doi.org/10.22543/2392-7674.1567

APA Style

Paunica, I., Constantin, V. D., Serban, D., Paius, C., Gaspar, B., Epistatu, D., Verlas, V., Sfetea, R., Andronache, L. F., Balalau, C., Bălan, D. G., Motofei, A. F., & Silaghi, A. (2024). Diabetes Mellitus and Associated Complications in the Digestive Tract. Journal of Mind and Medical Sciences, 11(2), 351-362. https://doi.org/10.22543/2392-7674.1567

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