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Volume 11
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10.22543/2392-7674.1548
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Journal of Mind and Medical Sciences is published by MDPI from Volume 12 Issue 1 (2025). Previous articles were published by another publisher in Open Access under a CC-BY (or CC-BY-NC-ND) licence, and they are hosted by MDPI on mdpi.com as a courtesy and upon agreement with Valparaiso University (ValpoScholar).
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Article

Challenges in Diagnosing Nasopharyngeal Tumors

by
Alexandru Aristide Alexe
1,2,
Mihai Victor Lupascu
1,2,*,
Haldun Septar
1,2,
Anca Pantea Stoian
3,
Andra Iulia Suceveanu
1,4,
Viorel Gherghina
1,5,
Iuliana Cindea
1,5,
Alina Doina Nicoara
1,6,
Laura Mazilu
1,7,
Razvan Hainarosie
8,
Felix Voinea
1,9 and
Adrian Paul Suceveanu
1,4
1
Faculty of Medicine, Ovidius University of Constanta, Constanta, Romania
2
Department of Otorhinolaryngology, St. Ap. Andrei Emergency County Hospital, Constanta, Romania
3
Department of Diabetes, Nutrition and Metabolic Disorders, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania
4
Department of Gastroenterology, St. Ap. Andrei Emergency County Hospital, Constanta, Romania
5
Department of Anaesthesia and Intensive Care, St. Ap. Andrei Emergency County Hospital, Constanta, Romania
6
Department of Internal Medicine, St. Ap. Andrei Emergency County Hospital, Constanta, Romania
7
Department of Oncology, Ovidius Clinical Hospital, Constanta, Romania
8
Department of Otorhinolaryngology, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania
9
Department of Urology, St. Ap. Andrei Emergency County Hospital, Constanta, Romania
*
Author to whom correspondence should be addressed.
J. Mind Med. Sci. 2024, 11(2), 437-443; https://doi.org/10.22543/2392-7674.1548
Submission received: 16 February 2024 / Revised: 16 March 2024 / Accepted: 24 June 2024 / Published: 31 October 2024

Abstract

Malignant nasopharyngeal tumors account for approximately 4% of ENT malignant tumor pathology and 1% of all cancers. The diagnosis of nasopharyngeal tumors is often late, the reason being the location in a silent anatomical region in terms of symptomatology and accessibility. Thus, approximately 70% of newly diagnosed patients with nasopharyngeal carcinoma unfortunately present with the condition in an advanced local stage. The early signs and symptoms are varied (nasal obstruction, hearing loss, otalgia, headache) and are usually ignored by the patient and even by the doctor in the initial stage of nasopharyngeal tumor evolution. Approximately 5% of patients have systemic metastases at presentation, the most common location being bone. Latent Epstein-Barr virus infection appears to be involved in the pathogenesis of nasopharyngeal carcinoma. There is no exact evidence of how often a nasopharynx tumor’s first sign is unilateral hearing loss. Thus, further work is required to determine that exactly to help patients get diagnosed faster and therefore improving their therapeutical options. This study aims to explore which symptoms are most common as the first indication of NPC, as well as how these symptoms compare to each other in terms of frequency and likelihood of occurrence.
Keywords: otitis media; nasopharyngeal cancer; nasopharynx tumor; Eustachian tube; Epstein-Barr virus otitis media; nasopharyngeal cancer; nasopharynx tumor; Eustachian tube; Epstein-Barr virus

Share and Cite

MDPI and ACS Style

Alexe, A.A.; Lupascu, M.V.; Septar, H.; Pantea Stoian, A.; Suceveanu, A.I.; Gherghina, V.; Cindea, I.; Nicoara, A.D.; Mazilu, L.; Hainarosie, R.; et al. Challenges in Diagnosing Nasopharyngeal Tumors. J. Mind Med. Sci. 2024, 11, 437-443. https://doi.org/10.22543/2392-7674.1548

AMA Style

Alexe AA, Lupascu MV, Septar H, Pantea Stoian A, Suceveanu AI, Gherghina V, Cindea I, Nicoara AD, Mazilu L, Hainarosie R, et al. Challenges in Diagnosing Nasopharyngeal Tumors. Journal of Mind and Medical Sciences. 2024; 11(2):437-443. https://doi.org/10.22543/2392-7674.1548

Chicago/Turabian Style

Alexe, Alexandru Aristide, Mihai Victor Lupascu, Haldun Septar, Anca Pantea Stoian, Andra Iulia Suceveanu, Viorel Gherghina, Iuliana Cindea, Alina Doina Nicoara, Laura Mazilu, Razvan Hainarosie, and et al. 2024. "Challenges in Diagnosing Nasopharyngeal Tumors" Journal of Mind and Medical Sciences 11, no. 2: 437-443. https://doi.org/10.22543/2392-7674.1548

APA Style

Alexe, A. A., Lupascu, M. V., Septar, H., Pantea Stoian, A., Suceveanu, A. I., Gherghina, V., Cindea, I., Nicoara, A. D., Mazilu, L., Hainarosie, R., Voinea, F., & Suceveanu, A. P. (2024). Challenges in Diagnosing Nasopharyngeal Tumors. Journal of Mind and Medical Sciences, 11(2), 437-443. https://doi.org/10.22543/2392-7674.1548

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