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Eng. Proc., 2024, IOCBE 2024

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8 pages, 1066 KiB  
Proceeding Paper
Comparison of the Effects of Essential Oils and Antibiotics on Listeria monocytogenes Isolates
by Vesna Kalaba, Dragica Đurđević-Milošević, Tanja Ilić and Dragana Kalaba
Eng. Proc. 2024, 81(1), 1; https://doi.org/10.3390/engproc2024081001 - 28 Nov 2024
Viewed by 590
Abstract
Food contamination with Listeria monocytogenes can cause health problems of increasing global concern. The resistance of L. monocytogenes to antibiotics requires finding alternative solutions to protect human health. This mini study was designed to evaluate the effects of antibiotics and some particular essential [...] Read more.
Food contamination with Listeria monocytogenes can cause health problems of increasing global concern. The resistance of L. monocytogenes to antibiotics requires finding alternative solutions to protect human health. This mini study was designed to evaluate the effects of antibiotics and some particular essential oils on L. monocytogenes isolates from food of animal origin and isolates from food-producing surfaces. This aim was to investigate the effects of seven antibiotics (amikacin, gentamicin, penicillin, cephalexin, ceftriaxone, tetracycline, and nalidixic acid) on L. monocytogenes isolated from food and surface samples. Also, the antibacterial activity of four essential oils (thyme, oregano, peppermint, and rosemary) against the growth of L. monocytogenes isolates was investigated. Listeria monocytogenes isolates were from food of an animal origin and food-producing surfaces. The isolation and determination of L. monocytogenes from food samples followed ISO 11290-1. Surface samplings were performed in compliance with ISO 18593, followed by the isolation and determination of L. monocytogenes. A disc diffusion method was used, and the tests were performed in triplicate. The results of this study confirmed the pronounced antibacterial activity of essential oils compared to antimicrobial drugs. The essential oil of Thymus vulgaris showed a bactericidal effect against all tested L. monocytogenes isolates. Full article
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8 pages, 3354 KiB  
Proceeding Paper
Electrospun Hyaluronan-Based Nanofibers with Mangiferin: Preparation, Morphology, and Drug Release Kinetics
by Roman Shaikenov, Vladislava Klimshina, Yuliya Generalova, Polina Serbun, Anna Kosova, Maksim Dorogov, Svetlana Morozkina and Petr Snetkov
Eng. Proc. 2024, 81(1), 2; https://doi.org/10.3390/engproc2024081002 - 28 Nov 2024
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Abstract
The rise in antibiotic-resistant bacterial infections is a major global health concern. The search for natural compounds that inhibit the growth of pathogens is becoming urgent. One such compound is mangiferin, a non-toxic polyphenolic compound derived mainly from Mangifera indica. In addition [...] Read more.
The rise in antibiotic-resistant bacterial infections is a major global health concern. The search for natural compounds that inhibit the growth of pathogens is becoming urgent. One such compound is mangiferin, a non-toxic polyphenolic compound derived mainly from Mangifera indica. In addition to antibacterial properties, it exhibits anticancer, antioxidant, immunomodulatory, analgesic and other activities. However, the clinical application of mangiferin is limited by poor solubility and bioavailability. This study describes mangiferin-loaded electrospun nanofibers based on high-molecular-weight hyaluronic acid. The nanofibers improve mangiferin delivery and possess favorable morphological characteristics and drug release kinetics, making them promising candidates for effective antibacterial dressings. This study found that an increase in the mangiferin content of the fibers led to an increase in the average diameter of the fibers. It was also found that nanofibers with different mangiferin content have similar release kinetics with an anomalous non-Fickian transport pattern: most of the mangiferin is released within 10–15 min. Full article
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12 pages, 2109 KiB  
Proceeding Paper
A Short Overview of the Formulation of Cellulose-Based Hydrogels and Their Biomedical Applications
by Raja Saadan, Aziz Ihammi, Mohamed Chigr and Ahmed Fatimi
Eng. Proc. 2024, 81(1), 3; https://doi.org/10.3390/engproc2024081003 - 20 Dec 2024
Viewed by 483
Abstract
Cellulose, the most abundant natural biopolymer, has garnered significant attention for hydrogel development due to its exceptional properties, including biocompatibility, biodegradability, renewability, and mechanical strength. These attributes make cellulose an environmentally friendly and safe material for biomedical engineering applications. Crosslinking is a critical [...] Read more.
Cellulose, the most abundant natural biopolymer, has garnered significant attention for hydrogel development due to its exceptional properties, including biocompatibility, biodegradability, renewability, and mechanical strength. These attributes make cellulose an environmentally friendly and safe material for biomedical engineering applications. Crosslinking is a critical step in hydrogel synthesis, enabling the formation of a 3D network that enhances structural and functional properties. Various crosslinking methods have been employed to tailor cellulose-based hydrogels for specific applications, such as tissue engineering, wound healing, drug delivery, and 3D bioprinting. This paper provides a concise overview of the formulation techniques and biomedical applications of cellulose-based hydrogels. By synthesizing recent advances from the literature, we highlight the unique advantages of cellulose-based hydrogels over other biomaterials and discuss their potential as a sustainable and innovative platform in biomedical engineering. Full article
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9 pages, 549 KiB  
Proceeding Paper
Biological Treatment of Second Cheese Whey Using Marine Microalgae/Cyanobacteria-Based Systems
by Stefania Patsialou, Ioanna Aikaterini Tsakona, Dimitris V. Vayenas and Athanasia G. Tekerlekopoulou
Eng. Proc. 2024, 81(1), 4; https://doi.org/10.3390/engproc2024081004 - 16 Jan 2025
Viewed by 331
Abstract
The biological treatment of second cheese whey (SCW) was investigated using two different marine cultures, the microalgae Picochlorum costavermella and the cyanobacterium Geitlerinema sp. Seawater from the coastal area of Rio, near Patras, was used for dilution of the SCW to achieve an [...] Read more.
The biological treatment of second cheese whey (SCW) was investigated using two different marine cultures, the microalgae Picochlorum costavermella and the cyanobacterium Geitlerinema sp. Seawater from the coastal area of Rio, near Patras, was used for dilution of the SCW to achieve an initial concentration of about 2000 mg d-COD/L in both cases without any external additions of the inorganic nutrients N and P. The growth of the mixed biomass, the removal of nutrients and the simultaneous accumulation of bioproducts over time were studied, with d-COD removal reaching 65% and maximum lipid and protein contents, up to 24% and 41.7%, respectively. Full article
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