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Oral, Volume 4, Issue 1 (March 2024) – 10 articles

Cover Story (view full-size image): The oral health/systemic health connection has been an area of research interest that increased dramatically during the 1990s. Periodontal disease has been associated with a number of systemic conditions, including cardiovascular disease, diabetes, pre-term low-birth-weight infants, respiratory conditions, rheumatoid arthritis, cancer, and Alzheimer’s disease. Inflammation is the obvious link that connects periodontal disease with these conditions, but is this association casual or causal? We will address the biologic plausibility, evidence from human studies, evidence from animal studies, and therapeutic interventions as we review the current understanding of the link between periodontitis and Alzheimer’s disease. View this paper
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13 pages, 920 KiB  
Review
The Most Common Types of Bias in a Human Bitemark Analysis
by Tayyaba Masood, Scheila Mânica and Hemlata Pandey
Oral 2024, 4(1), 113-125; https://doi.org/10.3390/oral4010010 - 7 Mar 2024
Viewed by 1493
Abstract
Given that some suspected perpetrators were wrongly convicted, a defective bitemark analysis is comparable to dentists’ most crucial clinical decisions regarding assessment. Bias affects human bitemark analysis beyond the limitation of the evidence itself. The aim of this study was to explore the [...] Read more.
Given that some suspected perpetrators were wrongly convicted, a defective bitemark analysis is comparable to dentists’ most crucial clinical decisions regarding assessment. Bias affects human bitemark analysis beyond the limitation of the evidence itself. The aim of this study was to explore the potential for different types of bias in bitemark analysis and the methods involved in that analysis by conducting a scoping review. Results showed that the 14 articles that explore the topic of bias in bitemark analysis were published from 2006-2022. Publications were from the USA mainly (n = 7), followed by the UK (n = 3), Australia (n = 2), New Zealand, (n = 1) and the Netherlands (n = 1). Of these publications, 36% addressed contextual bias, while 57% acknowledged cognitive bias. According to the findings, preventive measures consist of limiting the availability of unrelated data during research, employing several comparison samples for a more impartial assessment, and repeating the analysis while being blind to past findings. Nevertheless, the physical limitations of the evidence such as distortions are still strongly present. Full article
(This article belongs to the Special Issue Advances of Forensic Dentistry)
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12 pages, 9903 KiB  
Article
Evaluation of Enamel Volume Loss after Exposure to Energy Drinks
by Karen A. Schulze, Noëlle M. Santucci, Bina Surti, Stefan Habelitz, Mouchumi Bhattacharyya and Warden Noble
Oral 2024, 4(1), 101-112; https://doi.org/10.3390/oral4010009 - 23 Feb 2024
Cited by 1 | Viewed by 1849
Abstract
Objectives: This study was conducted to determine the erosive potential of various commercial energy drinks (EDs), sports drinks (SDs), and sugar sweetened beverages (SSBs) and to correlate quantitative changes in tooth enamel volume loss based on the pH and titratable acidity of the [...] Read more.
Objectives: This study was conducted to determine the erosive potential of various commercial energy drinks (EDs), sports drinks (SDs), and sugar sweetened beverages (SSBs) and to correlate quantitative changes in tooth enamel volume loss based on the pH and titratable acidity of the drinks. Methods: A flat plane on the facial surface of 36 human incisor teeth was created and embedded in sample holders using resin. After pre-scanning with a profilometer (Proscan 2000, Scantron, Ind Products Ltd., Taunton, UK), the six samples per group were immersed for 4 h into either Monster Energy™ (ED), Rockstar™ (ED), Red Bull™ (ED), or 5-h Energy™ (ED) and, for comparison with a sports drink, Gatorade™ (SD) and a sugar sweetened beverage, Coca-Cola® (SSB). After immersion and post-scanning, the quantitative volume loss of the tooth enamel of the 36 samples was calculated (Proscan 3D software V2.1.1.15B), and the pH and titratable acidity (TA) of each drink was determined. Results: All drinks tested caused enamel volume loss. The actual amount varied among the different drinks, from 0.39 mm3 for Red Bull™, up to 1.01 mm3 for Gatorade™. The pH measurements differed for each drink, ranging from 2.6 to 3.7. There was a small reverse correlation of 0.326 between the pH of all drinks and volume loss. Among the energy drinks, titratable acidity was similar and there was only a weak correlation between TA and volume loss (0.319 at p = 0.53). Conclusions: Energy drinks, sugar sweetened beverages, and sport drinks all have the potential to cause enamel tooth surface loss resulting in demineralization. Therefore, the pH of a drink cannot be the sole determinant for choosing a less harmful commercial beverage. Full article
(This article belongs to the Special Issue Current Issues in Oral Health)
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11 pages, 2129 KiB  
Article
Teaching of Forensic Dentistry in Khartoum, Sudan
by Sarah Hag Ali, Ademir Franco, Emilio Nuzzolese and Scheila Mânica
Oral 2024, 4(1), 90-100; https://doi.org/10.3390/oral4010008 - 4 Feb 2024
Viewed by 2127
Abstract
Background: Dental professionals assist with legal and criminal matters through the practice of forensic dentistry which has evolved over the past century and is now a crucial component of undergraduate dental education in many nations. The need for formal training in the subject [...] Read more.
Background: Dental professionals assist with legal and criminal matters through the practice of forensic dentistry which has evolved over the past century and is now a crucial component of undergraduate dental education in many nations. The need for formal training in the subject and its inclusion in dental curricula were acknowledged and addressed in the 1960s and 1970s. Aims: This study aimed to investigate the teaching of forensic dentistry in dental universities of Khartoum, Sudan, and to propose certain topics and teaching criteria to be standardized in forensic dentistry teaching in Sudan. Materials and methods: An observational, descriptive study was conducted, involving all undergraduate dental institutions in Khartoum, Sudan. Institutional websites were searched using the Google search engine to obtain the dental program curricula in English. The curricula were then analyzed to identify the presence of forensic odontology/dentistry teaching. Results: Of the 19 universities included in the study, five (26.3%) teach forensic dentistry in their undergraduate curricula, whereas 12 (63.1%) do not. Two universities (10.6%) indicated the presence of forensic dentistry teaching in their curricula but did not provide actual instruction. The teaching of forensic dentistry mainly occurred during the second, third, and fourth years of the dental program. Three universities considered it an independent subject, while two universities incorporated it into oral and maxillofacial pathology. Four universities provided lectures only, while one university combined lectures and practical sessions. Qualified forensic dentists taught the subject in four universities, while one university had general dentists as instructors. The main topics delivered are: (1) introduction to forensics, (2) human identification, (3) dental age estimation, (4) interpretation of bitemarks, (5) DNA in forensics, and (6) child abuse. Conclusion: Forensic dentistry training is currently undervalued in Sudan due to various limitations. It is recommended that all dental schools in Sudan offer opportunities for students to learn and become acquainted with forensic dentistry as part of their dental programs. The Sudanese Dental Council should establish formal coordination with academic institutions and experienced forensic dentists to ensure the quality and relevance of the proposed modular course within the educational system. Finally, additional topics including dental record-keeping and dental malpractice are suggested for inclusion in the current modules. Full article
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16 pages, 723 KiB  
Review
Treatment Strategies for Incisors of Children Affected by Molar Incisor Hypomineralization: A Narrative Review
by Berkant Sezer and Burak Çarıkçıoğlu
Oral 2024, 4(1), 74-89; https://doi.org/10.3390/oral4010007 - 1 Feb 2024
Viewed by 2263
Abstract
Today, molar incisor hypomineralization (MIH), which affects approximately one in seven children, is defined as a hypomineralized developmental enamel defect that often impacts at least one permanent first molar and frequently affects permanent incisors as well. Symptoms and signs include demarcated opacities of [...] Read more.
Today, molar incisor hypomineralization (MIH), which affects approximately one in seven children, is defined as a hypomineralized developmental enamel defect that often impacts at least one permanent first molar and frequently affects permanent incisors as well. Symptoms and signs include demarcated opacities of various colors, post-eruptive enamel deterioration, atypical caries and restorations, hypersensitivity, tooth loss due to MIH, and difficulty in achieving anesthesia. A detailed review of the scientific literature shows that there are many studies evaluating different treatment approaches for permanent first molars affected by MIH. On the other hand, there are very few scientific studies evaluating treatment approaches for affected incisors in patients with MIH. Most of these studies consist of case reports or series. White/creamy and/or yellow/brown demarcated opacities are commonly observed in affected incisors in patients with MIH. While these opacities increase the susceptibility of enamel to deterioration and dental caries, they also cause aesthetic problems and related psychosocial consequences. Treatment methods, such as resin infiltration, microabrasion, and/or dental bleaching, have been proposed for aesthetic and restorative purposes in affected incisors in patients with MIH. Additionally, various approaches to increase mineral content and relieve hypersensitivity have been recommended. The number of randomized controlled and prospective studies is quite low, but many case reports and case series have been encountered. The purpose of this review was to provide a comprehensive overview of the different treatment management modalities for permanent incisors affected by MIH. As a result, while resin infiltration, dental bleaching, microabrasion, and/or etch–bleach–seal techniques are preferred for aesthetic and restorative purposes in these teeth, it has been observed that agents containing casein phosphopeptide amorphous calcium phosphate, casein phosphopeptide amorphous calcium fluoride phosphate, fluoride, and calcium glycerophosphate increase the mineral content. Additionally, studies have reported that ozone and low-level laser therapy, in addition to these remineralizing agents, reduce hypersensitivity in these teeth. Although the findings of this review indicate that the level of evidence for current approaches is not high, clinicians may prefer one or more of the treatment approaches mentioned in this article based on experience and patient expectations. Full article
(This article belongs to the Special Issue Current Issues in Oral Health)
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13 pages, 626 KiB  
Review
Periodontitis and Alzheimer’s Disease: Is There a Connection?
by William Lundergan, Kavitha Parthasarathy and Navid Knight
Oral 2024, 4(1), 61-73; https://doi.org/10.3390/oral4010006 - 22 Jan 2024
Cited by 1 | Viewed by 4197
Abstract
The oral health/systemic health connection has been an area of research interest that increased dramatically during the 1990s. Periodontal disease has been associated with a number of systemic conditions, including cardiovascular disease, diabetes, pre-term low-birth-weight infants, respiratory conditions, rheumatoid arthritis, cancer, and Alzheimer’s [...] Read more.
The oral health/systemic health connection has been an area of research interest that increased dramatically during the 1990s. Periodontal disease has been associated with a number of systemic conditions, including cardiovascular disease, diabetes, pre-term low-birth-weight infants, respiratory conditions, rheumatoid arthritis, cancer, and Alzheimer’s disease. Inflammation is the obvious link that connects periodontal disease with these conditions, but is this association casual or causal? We will address the biologic plausibility, evidence from human studies, evidence from animal studies, and therapeutic interventions as we review the current understanding of the link between periodontitis and Alzheimer’s disease. Full article
(This article belongs to the Special Issue Current Issues in Oral Health)
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11 pages, 753 KiB  
Review
Intentional Dental Modifications in the African Population
by Candy Kgabi, Scheila Manica and Hemlata Pandey
Oral 2024, 4(1), 50-60; https://doi.org/10.3390/oral4010005 - 18 Jan 2024
Viewed by 2706
Abstract
(1) This research paper aims to conduct a comprehensive review of the existing scientific literature on intentional dental modifications within the African population. By synthesizing and analysing studies, this paper aims to shed light on the prevalence, cultural significance, and forensic implications of [...] Read more.
(1) This research paper aims to conduct a comprehensive review of the existing scientific literature on intentional dental modifications within the African population. By synthesizing and analysing studies, this paper aims to shed light on the prevalence, cultural significance, and forensic implications of intentional dental modifications. (2) A scoping review was conducted according to PRISMA for Scoping Reviews and a search performed in June 2023 on the three electronic databases Scopus, PubMed, and Web of Science. (3) The search resulted in 30 studies and showed that intentional dental modifications, also referred to as nontherapeutic dental modifications, are prevalent across the African population for reasons linked to traditional medicine, ethnic affiliation, and individualism, with the highest-reported modification being infant oral mutilation at 53%, followed by tooth filing at 10%, and others such as lip plates, diastema piercings, dental avulsion, dental tattooing, crowns, and oral piercings. (4) The quality and quantity of the available literature on intentional dental modifications in the African population is limited due to bias in reporting, as most studies are those of individuals with severe health complications. The data gathered from this study could further aid in the analysis and identification of nontherapeutic dental modifications, be used in profiling, and assist in the estimation of population affiliation. Full article
(This article belongs to the Special Issue Advances of Forensic Dentistry)
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14 pages, 2004 KiB  
Article
Effectiveness of Bioactive Toothpastes against Dentin Hypersensitivity Using Evaporative and Tactile Analyses: A Randomized Clinical Trial
by Roberta Caroline Bruschi Alonso, Letícia de Oliveira, Jaqueline Alves Batista Silva, Williane Bernadete Bezerra dos Santos, Lúria Ribeiro de Souza Laranja Ferreira, Ricardo Danil Guiraldo, Fabiano Vieira Vilhena and Paulo Henrique Perlatti D’Alpino
Oral 2024, 4(1), 36-49; https://doi.org/10.3390/oral4010004 - 10 Jan 2024
Cited by 1 | Viewed by 3171
Abstract
The objective of this study was to investigate and compare the effectiveness of toothpastes containing bioactives to relieve dentin hypersensitivity with that of a commercial desensitizing toothpaste containing REFIX technology, associated or not with a calcium booster. In this double-blind, randomized, parallel-group, multi-center [...] Read more.
The objective of this study was to investigate and compare the effectiveness of toothpastes containing bioactives to relieve dentin hypersensitivity with that of a commercial desensitizing toothpaste containing REFIX technology, associated or not with a calcium booster. In this double-blind, randomized, parallel-group, multi-center clinical trial, thirty-two volunteers diagnosed with dentin hypersensitivity and qualified to participate were randomized into four groups: (1) Colgate Sensitive Pro-Relief; (2) Sensodyne Repair & Relief; (3) Regenerador Sensitive; and (4) Regenerador Sensitive, associated with a calcium booster. Evaporative and tactile tests were used to check for dentin hypersensitivity in the test subjects. The participants brushed their teeth with one of the toothpastes, and dentin hypersensitivity was immediately tested using a visual analogue scale (VAS), in which the pain was rated on a scale of 0 to 10. Dentin hypersensitivity was measured after one week and after one month of the subjects continuing to use the toothpaste three times per day. Data were statistically analyzed with a non-parametric Friedman test for dependent data (α = 0.05). All toothpastes reduced dentin hypersensitivity. In the evaporative test, Sensodyne Protect & Repair and Regenerador Sensitive, associated with the calcium booster, exhibited faster and more effective results in reducing pain caused by dentin hypersensitivity, even after the first use. Colgate Sensitive Pro-Relief was effective only after one week of use. All toothpastes performed well in the tactile test for treating dentin hypersensitivity, and their performance improved over time. Sensodyne Repair & Protect presented the highest overall pain remission after one month (84.6%). The bioactive toothpastes reduced, to a different extent, the tooth hypersensitivity reported by the volunteers. Sensodyne Repair & Relief and Regenerador Sensitive, associated or not with a calcium booster, presented faster and more effective results in reducing pain caused by dentin hypersensitivity. Full article
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13 pages, 488 KiB  
Review
Future Prospects and Challenges in Additive Manufacturing for Complete Dentures: A Narrative Review
by Mariya Dimitrova, Angelina Vlahova, Yavor Kalachev, Rada Kazakova and Saverio Capodiferro
Oral 2024, 4(1), 23-35; https://doi.org/10.3390/oral4010003 - 26 Dec 2023
Cited by 2 | Viewed by 1941
Abstract
The utilization of computer-assisted design and computer-assisted manufacturing (CAD/CAM) techniques in the creation of complete dentures (CDs) has piqued the interest of many people. This article seeks to provide a comprehensive, critical, and objective analysis of the current knowledge of CDs and related [...] Read more.
The utilization of computer-assisted design and computer-assisted manufacturing (CAD/CAM) techniques in the creation of complete dentures (CDs) has piqued the interest of many people. This article seeks to provide a comprehensive, critical, and objective analysis of the current knowledge of CDs and related technology. The aim of this study is to assess existing literature concerning 3D-printed complete dentures, covering aspects like innovative biomaterials, manufacturing methods and processes, workflow, and clinical effectiveness. The design of the current study included an initial review of 172 titles, an appraisal of abstracts, and finally a selection of articles for rigorous textual analysis. Inconsistencies discovered throughout the selection process were amicably resolved through discourse, culminating in the identification of 65 items. The publications retrieved from a thorough search of the PubMed, Scopus, and Embase databases spanned the years 1994 to 2023. Contemporary digital technology provides evident advantages, but its successful incorporation necessitates meticulous preparation. In the realm of dental healthcare, the digital workflow showcases versatility and a range of applications. Full article
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14 pages, 2898 KiB  
Review
Zirconia Implants: A Mapping Review
by Steven J. Sadowsky
Oral 2024, 4(1), 9-22; https://doi.org/10.3390/oral4010002 - 25 Dec 2023
Cited by 1 | Viewed by 2173
Abstract
The advent of zirconia ceramics with excellent mechanical, biomechanical, and optical properties has made them attractive metal-free substitutes for titanium implants. Both animal and human studies have documented shortcomings with titanium implants. A mapping review of the current literature on three iterations of [...] Read more.
The advent of zirconia ceramics with excellent mechanical, biomechanical, and optical properties has made them attractive metal-free substitutes for titanium implants. Both animal and human studies have documented shortcomings with titanium implants. A mapping review of the current literature on three iterations of zirconia implant designs has been challenging due to heterogeneous success data and limited follow-up. Zirconia implants hold promise for a new generation of dental implants, but technical developments are needed for design and material enhancements that will need to be validated by long-term rigorous studies. Full article
(This article belongs to the Special Issue Current Issues in Oral Health)
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8 pages, 447 KiB  
Article
The Use of Fine Arts to Enhance Visualization and Describing Skills in a First-Year Dental Anatomy Course: A Qualitative Study
by Geetha Siddanna, Bradley Smith, Andrea Mantesso, Vidya Ramaswamy, Tracy de Peralta and Elisabeta Karl
Oral 2024, 4(1), 1-8; https://doi.org/10.3390/oral4010001 - 21 Dec 2023
Cited by 2 | Viewed by 1102
Abstract
(1) Background: In this qualitative study, we investigated the implementation of an art-based observation workshop as a tool to improve visualization and interpretation skills in a cohort of first-year dental students (N = 109) in a dental anatomy course. (2) Methods: The art [...] Read more.
(1) Background: In this qualitative study, we investigated the implementation of an art-based observation workshop as a tool to improve visualization and interpretation skills in a cohort of first-year dental students (N = 109) in a dental anatomy course. (2) Methods: The art workshop was held once for a total of 60 min in the pre-clinical simulation laboratory, which is the regular teaching setting for the dental anatomy course. Visualization and interpretation skills were assessed before (pre-test) and after the art-based observation workshop (post-test). The pre- and post-tests contained five images that guided students to describe dental anatomy images. The pre- and post-test had different but similar images. Dental students accessed the pre- and post-tests on CANVAS and recorded their answers. After that, the audio recording files were analyzed and compared to determine the frequency of use of dental anatomy-specific nomenclature while answering the pre- and post-test. (3) Results: Our results demonstrate that students used dental anatomy-specific nomenclature more frequently after the intervention. (4) Conclusions: we have concluded that students’ use of dental anatomy nomenclature in the first-year dental anatomy curriculum is enhanced following an art-based intervention in a regular dental simulation laboratory. Full article
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