Anatomy for Modern Urology

A special issue of Anatomia (ISSN 2813-0545).

Deadline for manuscript submissions: 15 December 2024 | Viewed by 8826

Special Issue Editor


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Guest Editor
Department of Urology and Clinical Research Group on Predictive Onco-Urology, Sorbonne University, 75013 Paris, France
Interests: prostate; kidney; urology; prostate cancer; bladder cancer; urologic oncology; anatomy; DNA microarray; predictive medicine

Special Issue Information

Dear Colleagues,

I am pleased to introduce a Special Issue on anatomy for modern urology. Technological innovations and molecular discoveries change the basement of medicine and interventional practices in urology and open a new era. The field of urology deals with diseases of the urinary system and genital male organs, requiring multidisciplinary approaches. These new insights also move the field of morphological sciences to adapt the anatomical knowledge and morphological models to the innovations and facilitate their translation in practice. The more recent aspects of gross and microscopic anatomy in urology which require comprehensive morphological knowledge for practice or biological research are delivered in this Special Issue. The new approaches using information technology and virtual anatomy to reduce the learning curve in interventional radiology and surgery to treat urological diseases are also mentioned. This Special Issue seeks reviews and original papers covering a wide range of hot topics related to new studies around clinical and radiological anatomy, uropathology, the functional and molecular aspects of aging, and diseases in the field of urology. New teaching approaches and research methodologies for urological sciences are also welcome.

We hope that this Special Issue under the scope of anatomy will provide a comprehensive and enthusiastic view to integrate morphological and urological sciences within the most recent progress of the health innovations.

Topics of interest include, but are not limited to:

  1. Geometric anatomy of the prostate for IRE focal ablation;
  2. The edges of the prostate and instrumental surgery;
  3. The spatial genomics of zonal anatomy and cell compartments in the prostate gland;
  4. Advances in the neuroanatomy of the bladder;
  5. The clinical relevance of virtual and printed 3D models for kidney surgery;
  6. Practical review of the virtual anatomy atlas and simulators for young urologists;
  7. Advances in the functional anatomy of the penis.

Prof. Dr. Olivier Cussenot
Guest Editor

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Keywords

  • urology
  • uropathology
  • molecular urology
  • radiological anatomy
  • surgical anatomy
  • kidney
  • urinary tract
  • bladder
  • prostate
  • urinary system
  • male genital organs
  • virtual anatomy
  • digital imaging
  • 3D models
  • retroperitoneum

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Published Papers (3 papers)

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Review

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20 pages, 3416 KiB  
Review
Molecular Anatomy of Prostate Cancer and Its Implications in Active Surveillance and Early Intervention Strategies
by Sandy Figiel, Géraldine Cancel-Tassin, Ian G. Mills, Alastair D. Lamb, Gaelle Fromont and Olivier Cussenot
Anatomia 2023, 2(4), 300-319; https://doi.org/10.3390/anatomia2040027 - 10 Oct 2023
Viewed by 3272
Abstract
Understanding prostate carcinogenesis is crucial not only for identifying new treatment targets but also for developing effective strategies to manage the asymptomatic form of the disease. There is a lack of consensus about predicting the indolent form of the disease prostate cancer, leading [...] Read more.
Understanding prostate carcinogenesis is crucial not only for identifying new treatment targets but also for developing effective strategies to manage the asymptomatic form of the disease. There is a lack of consensus about predicting the indolent form of the disease prostate cancer, leading to uncertainties regarding treatment initiation. This review aims to enhance the assessment and management of early prostate cancer by providing a comprehensive picture of the molecular anatomy of the prostate, synthesising current evidence, highlighting knowledge gaps, and identifying future directions. It presents evidence for the efficacy of active surveillance as an alternative treatment strategy and its potential benefits in specific patient groups through androgen receptor disruption. Overall, an improved understanding of prostate carcinogenesis and its molecular underpinnings can pave the way for tailored and precise management approaches for this common cancer. Further development and validation of molecule-based assessment tools are needed. Integrating genomic, proteomic, and phenotypic models, as well as functional approaches, can help predict outcomes. This facilitates selecting candidates for active surveillance and targeting interventions for higher-risk cases, contributing to more precise management strategies. Full article
(This article belongs to the Special Issue Anatomy for Modern Urology)
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Other

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8 pages, 2790 KiB  
Opinion
The Prostate Is Not a Pill and Therefore Has No Capsule
by Johannes Kläger, Gabriel Wasinger, André Oszwald and Eva Compérat
Anatomia 2023, 2(3), 253-260; https://doi.org/10.3390/anatomia2030023 - 14 Aug 2023
Viewed by 2563
Abstract
Tumor staging of prostate cancer is a fundamental principle in management and therapy, with a hallmark being tumor growth beyond the organ boundary. Often, this is referred to as “capsule penetration”, suggesting the existence of a true prostatic capsule that would facilitate the [...] Read more.
Tumor staging of prostate cancer is a fundamental principle in management and therapy, with a hallmark being tumor growth beyond the organ boundary. Often, this is referred to as “capsule penetration”, suggesting the existence of a true prostatic capsule that would facilitate the determination of tumor penetration. In fact, the prostate does not have a true capsule and, depending on the anatomic area, it blends with the surrounding fibrous, adipose and muscular tissue. This makes it sometimes difficult or impossible to unequivocally identify extraprostatic tumor extension. It is necessary to appreciate this difficulty in order to better understand the significance of extraprostatic tumor extension. Full article
(This article belongs to the Special Issue Anatomy for Modern Urology)
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11 pages, 2526 KiB  
Opinion
Geometric Anatomy Basis for Safe and Effective Focal Ablation of Prostate Cancer by Irreversible Electroporation (IRE)
by Olivier Cussenot, Ruth Macpherson, Tom Leslie, Luca Lunelli, Giancarlo Marra, Marc Laniado, Freddie C. Hamdy and Richard J. Bryant
Anatomia 2023, 2(3), 232-242; https://doi.org/10.3390/anatomia2030021 - 4 Aug 2023
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Abstract
Irreversible electroporation (IRE) is a recent and minimally invasive method of partial prostate ablation. However, knowledge of the essential landmarks of prostate anatomy is crucial to achieving safe and effective partial ablation by IRE. High-quality imaging of the prostate is essential before the [...] Read more.
Irreversible electroporation (IRE) is a recent and minimally invasive method of partial prostate ablation. However, knowledge of the essential landmarks of prostate anatomy is crucial to achieving safe and effective partial ablation by IRE. High-quality imaging of the prostate is essential before the procedure. The individual morphological pattern of the prostate must be taken into account and detailed mapping with measurement of the lesion is necessary to determine optimal needle placement. The entire tumour volume must be covered while ensuring the safety of critical anatomical structures such as the rectum, urethra, nerve bundles and sphincter muscle. Full article
(This article belongs to the Special Issue Anatomy for Modern Urology)
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