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Anatomia
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From Anatomy to Clinical Neurosciences
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From Anatomy to Clinical Neurosciences

A special issue of Anatomia (ISSN 2813-0545).

Deadline for manuscript submissions: 31 January 2025 | Viewed by 2276

Special Issue Editor

Dr. Adel Maklad

E-Mail Website
Guest Editor
1. Department of Medical Education, College of Medicine and Life Sciences, University of Toledo, Toledo, OH 43614, USA
2. Department of Neurosciences, College of Medicine and Life Sciences, University of Toledo, Toledo, OH 43614, USA
Interests: neurobiology; vestivular neurosciences; inner ear evolution

Special Issue Information

Dear Colleagues,

Anatomical sciences is an umbrella that encompass anatomy, neuroscience, histology and cell biology, and embryology. Furthermore, anthrobiology as a discipline is tightly related to anatomy, since it entails morphometric studies of the human body. The close relationship of the subdisciplines of anatomy may hold true in a pedagogical sense; however, these different disciplines are highly divergent. Even within one of anatomy, such as neuroscience, there are several research topics and interests, such as neural devlopment, functional neurosciences, and neuroimaging. The current Special Issue aims to determine areas of commonality between these different emergent reasearch interests.

Dr. Adel Maklad
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Anatomia is an international peer-reviewed open access quarterly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1000 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • gross anatomy
  • functional anatomy
  • microscopic anatomy
  • developmental neurosciences
  • functional neuroanatomy
  • sensory systems
  • developmental biology
  • pedagogical anatomy

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Published Papers (2 papers)

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Research

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8 pages, 793 KiB  
Communication
Effects of Congenital Adrenal Hyperplasia (CAH) and Biological Sex on Brain Size
by Eileen Luders, Christian Gaser, Debra Spencer, Ajay Thankamony, Ieuan Hughes, Umasuthan Srirangalingam, Helena Gleeson, Melissa Hines and Florian Kurth
Anatomia 2024, 3(3), 155-162; https://doi.org/10.3390/anatomia3030012 - 18 Jul 2024
Cited by 1 | Viewed by 1133
Abstract
Congenital Adrenal Hyperplasia (CAH) has been reported to involve structural alterations in some brain regions. However, it remains to be established whether there is also an impact on the size of the brain as a whole. Here, we compiled the largest CAH sample [...] Read more.
Congenital Adrenal Hyperplasia (CAH) has been reported to involve structural alterations in some brain regions. However, it remains to be established whether there is also an impact on the size of the brain as a whole. Here, we compiled the largest CAH sample to date (n = 53), matched pair-wise to a control group (n = 53) on sex, age, and verbal intelligence. Using T1-weighted brain scans, we calculated intracranial volume (ICV) as well as total brain volume (TBV), which are both common estimates for brain size. The statistical analysis was performed using a general linear model assessing the effects of CAH (CAH vs. controls), sex (women vs. men), and any CAH-by-sex interaction. The outcomes were comparable for ICV and TBV, i.e., there was no significant main effect of CAH and no significant CAH-by-sex interaction. However, there was a significant main effect of sex, with larger ICVs and TBVs in men than in women. Our findings contribute to an understudied field of research exploring brain anatomy in CAH. In contrast to some existing studies suggesting a smaller brain size in CAH, we did not observe such an effect. In other words, ICV and TBV in women and men with CAH did not differ significantly from those in controls. Notwithstanding, we observed the well-known sex difference in brain size (12.69% for ICV and 12.50% for TBV), with larger volumes in men than in women, which is in agreement with the existing literature. Full article
(This article belongs to the Special Issue From Anatomy to Clinical Neurosciences)
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Other

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6 pages, 554 KiB  
Case Report
Transnasal Brain Sampling for Human Rabies Diagnosis
by Moses Barima Djimatey, Abdul-Rahim Abubakar, Augustina Angelina Sylverken, Theophilus Odoom, Braimah Baba Abubakari, John Akwasi Ohemeng, Gowri Yale, Frederic Lohr, Luke Gamble and Anita Mahadevan
Anatomia 2024, 3(4), 221-226; https://doi.org/10.3390/anatomia3040018 - 25 Sep 2024
Viewed by 621
Abstract
Introduction: Rabies remains a significant global threat, yet accurate estimations of its impact are hindered by the lack of confirmatory diagnoses. Postmortem diagnosis of rabies traditionally involves invasive brain tissue testing, a process met with resistance from deceased patients’ families, impeding consent. This [...] Read more.
Introduction: Rabies remains a significant global threat, yet accurate estimations of its impact are hindered by the lack of confirmatory diagnoses. Postmortem diagnosis of rabies traditionally involves invasive brain tissue testing, a process met with resistance from deceased patients’ families, impeding consent. This paper presents and evaluates an innovative yet unpublished transnasal approach for postmortem brain tissue collection, offering a minimally invasive, easier, faster, and safer method. This method preserves the cadaver’s integrity, potentially easing family reluctance towards autopsies. The limited testing of both human and animal rabies in Ghana highlights the challenges in diagnosing this fatal disease. Scarce diagnostic resources and the complexity of obtaining brain tissue samples exacerbate the issue. Cultural and religious beliefs surrounding autopsies contribute to familial hesitation, as families view these procedures as disruptive and disfiguring, further complicating consent. Methodology: The transnasal technique involves approaching the brain tissue through the nostrils and cribriform plate without any superficial manipulation of the patient’s head and face, thereby preserving the aesthetics and natural features of the person. Results: Technological advancements and seamless One Health collaboration among governmental, non-governmental, and research entities locally and globally have culminated in Ghana’s first confirmed rabies diagnosis using this method of brain tissue collection. This success emphasizes the efficiency and feasibility of the transnasal brain collection approach and the invaluable role of the One Health approach and collaborative efforts in overcoming diagnostic challenges in rabies control. Full article
(This article belongs to the Special Issue From Anatomy to Clinical Neurosciences)
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