Bacterial Resistome and Antimicrobial Resistance in Animal Infectious Diseases

Dear Colleagues,

The bacterial resistome refers to the collective genes within a bacterial population responsible for antibiotic resistance. These genes can be located on the bacterial chromosome or on plasmids, which are small, circular pieces of DNA that can be transferred between bacteria. The resistome includes genes that encode for various mechanisms of antibiotic resistance, such as efflux pumps that can pump antibiotics out of the cell, enzymes that can modify or degrade antibiotics, and mutations in antibiotic target sites that render antibiotics ineffective.

Antibiotic resistance is a growing concern in veterinary medicine, as is also the case in human medicine. Antibiotics are commonly used in veterinary medicine to treat bacterial infections in animals, and the overuse as well as misuse of antibiotics can lead to the development of antibiotic-resistant bacteria. Animals infected with antibiotic-resistant bacteria may require more intensive treatment and may be at a higher risk of developing complications or experiencing prolonged illness. Furthermore, there is a risk that antibiotic-resistant bacteria can be transmitted from animals to humans through direct contact or the consumption of contaminated food products. This can make it more difficult to treat human infections and lead to more severe public health concerns. Understanding the bacterial resistome is essential for developing strategies with which to combat antibiotic resistance, such as developing antibiotics or alternative treatments that target the resistance mechanisms.

"Antibiotics" is a multidisciplinary journal encompassing biochemistry, chemistry, genetics, microbiology, and pharmacology. Scientists are encouraged to publish their experimental and theoretical results in as much detail as possible. The evaluation of the resistome, therefore, seems to be one of the most current topics for the compression of antibiotic resistance.

Dr. Paolo Capozza
Dr. Nicola Pugliese
Prof. Dr. Maria Tempesta
Guest Editors

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• bacterial resistome
• antimicrobial resistance
• animal Infectious diseases
• veterinary medicine