Phage and Antibiotic Synergy
A special issue of Antibiotics (ISSN 2079-6382). This special issue belongs to the section "Bacteriophages".
Deadline for manuscript submissions: closed (31 January 2022) | Viewed by 11349
Special Issue Editor
Interests: inhaled phage therapeutics; phage therapy; phage formulation; respiratory infections
Special Issue Information
Dear Colleagues,
With the global misuse of antibiotics, the rapid emergence of multidrug-resistant (and even pandrug-resistant) bacteria is occurring worldwide. More bacterial infections are becoming difficult to treat, and are often associated with high morbidity, mortality and financial burden. Bacteriophages (or phages) are natural predators of bacteria that have the potential to revolutionize the treatment of multidrug-resistant bacterial infections. Over the past decade, phage therapy has been reconsidered as an alternative and/or adjunct to antibiotic therapy in Western countries. More recently, phage and antibiotic synergy has attracted attention due to marked improvement in efficacy and a reduced risk of developing phage- and antibiotic-resistant isolates. Numerous in vitro and in vivo studies have been conducted to better understand the synergy and underlying mechanisms, as well as to demonstrate efficacy against planktonic cells and biofilms.
Phage and antibiotic synergy—from basic science to in vivo studies—is a rapidly evolving field and this Special Issue of Antibiotics seeks to bring together manuscripts to enhance our understanding of phage and antibiotic synergy. We are gathering contributions in the form of original research articles, short communications, and critical narrative or systematic reviews covering all aspects of phage and antibiotic synergy, including, but not limited to, systemic identification of synergistic pair of phage and antibiotic, formulation of the pair, the mechanisms underlying synergy, and in vitro and in vivo efficacy and safety studies.
Dr. Rachel Yoon Chang
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
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Keywords
- Bacteriophage (phage)
- Phage therapy
- Phage and antibiotic synergy (PAS)
- Antimicrobial resistance
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