Oxidative Stress in Metabolic Disorders and Non-Communicable Diseases (NCDs): Molecular Pathways and Genetic Influence

A special issue of Antioxidants (ISSN 2076-3921). This special issue belongs to the section "Health Outcomes of Antioxidants and Oxidative Stress".

Deadline for manuscript submissions: 31 July 2025 | Viewed by 27

Special Issue Editor


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Guest Editor
Dipartimento di Scienze biomediche, Università degli Studi di Sassari, Sassari, Italy
Interests: endothelial cells; gene regulation; reactive oxygen species

Special Issue Information

Dear Colleagues,

Oxidative stress plays a pivotal role in the pathogenesis of various metabolic disorders and non-communicable diseases (NCDs), acting as a critical mediator of cellular damage and dysregulation. The intricate interplay between oxidative stress, molecular pathways, and genetic predisposition has garnered increasing attention in recent years. Reactive oxygen species (ROS), along with their regulatory networks, significantly impact metabolic processes, inflammation, and disease progression, contributing to conditions such as diabetes, cardiovascular diseases, neurodegenerative disorders, and cancer.

We are pleased to announce a call for papers for a Special Issue titled "Oxidative Stress in Metabolic Disorders and Non-Communicable Diseases (NCDs): Molecular Pathways and Genetic Influence". This Special Issue aims to explore the latest advancements in understanding the molecular and genetic mechanisms underlying oxidative stress in these diseases and to identify potential therapeutic targets and strategies.

We invite you to submit your original research, reviews, or methodological studies that address, but are not limited to, the following topics:

  • Molecular mechanisms of oxidative stress in metabolic disorders and NCDs;
  • Genetic susceptibility and epigenetic modifications influencing oxidative stress responses;
  • Crosstalk between oxidative stress and inflammation in disease pathogenesis;
  • Role of antioxidant enzymes and their regulation in cellular homeostasis;
  • Emerging therapies targeting oxidative stress in metabolic and non-communicable diseases;
  • Experimental and computational approaches to study oxidative stress pathways;
  • Biomarkers of oxidative stress and their clinical significance.

Submissions that provide insights into both in vitro and in vivo models or that propose translational approaches to mitigate oxidative stress are highly encouraged.

We look forward to receiving your valuable contributions, which will help advance the understanding of oxidative stress and its impact on metabolic and non-communicable diseases.

Dr. Roberta Giordo
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Antioxidants is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • metabolic disorders
  • non-communicable diseases (NCDs)
  • reactive oxygen species (ROS)
  • genetic influence
  • molecular pathways

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Published Papers

This special issue is now open for submission.
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