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Innovative Applications of Novel Natural Products in Medicinal and Agricultural Research

A special issue of Applied Sciences (ISSN 2076-3417). This special issue belongs to the section "Agricultural Science and Technology".

Deadline for manuscript submissions: 20 February 2025 | Viewed by 2272

Special Issue Editor

Dr. Martin C. Gruhlke

E-Mail Website
Guest Editor
Society for Natural Product and Drug Research, 52070 Aachen, Germany
Interests: natural products; active ingredient; molecular biology; biochemistry; apoptosis
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

We extend a warm invitation for you to contribute to our upcoming Special Issue of Applied Sciences, entitled "Innovative Applications of Novel Natural Products in Medicinal and Agricultural Research". This Special Issue promises to be an exciting platform where groundbreaking research, novel discoveries, and game-changing applications of natural products will be showcased.

We cordially invite researchers and scientists working in the fields of medicine and agriculture to contribute their valuable insights and innovative findings. By sharing your expertise, you will be contributing to the expansion of knowledge and the potential impact of natural products in addressing critical challenges in health and agriculture.

For our readers, we promise an insightful collection of articles that explore the vast potential of nature's offerings in advancing human and environmental well-being. This Special Issue aims to serve as a reference for researchers, practitioners, and policymakers seeking innovative solutions derived from natural sources.

Together, let us uncover the untapped potential of natural products and pave the way for a healthier and more sustainable future.

With warm regards,

Dr. Martin C. Gruhlke
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Applied Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • natural products
  • medicinal research
  • agricultural applications
  • bioactive compounds
  • drug discovery

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Published Papers (1 paper)

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Research

12 pages, 1223 KiB  
Article
Date Industry by-Product: Date Seeds (Phoenix dactylifera L.) as Potential Natural Sources of Bioactive and Antioxidant Compounds
by Arwa Ali Zarie, Amro B. Hassan, Ghedeir M. Alshammari, Mohammed Abdo Yahya and Magdi A. Osman
Appl. Sci. 2023, 13(21), 11922; https://doi.org/10.3390/app132111922 - 31 Oct 2023
Cited by 3 | Viewed by 1880
Abstract
The chemical composition, carotenoids, anthocyanins, total phenolic content, total flavonoid content, and antioxidant activity of three date seed cultivars, mainly Barhi, Ruthana, and Qatarah, were investigated. Date seed bioactive compounds were extracted by using different extraction solvents. The chemical analysis revealed that the [...] Read more.
The chemical composition, carotenoids, anthocyanins, total phenolic content, total flavonoid content, and antioxidant activity of three date seed cultivars, mainly Barhi, Ruthana, and Qatarah, were investigated. Date seed bioactive compounds were extracted by using different extraction solvents. The chemical analysis revealed that the Barhi cultivar has the highest moisture and fat content, while Ruthana has the highest carbohydrate content. There were no significant differences in protein and ash contents among the three date seeds. Ethanol (100%) showed the highest bioactive compound contents and antioxidant activity, whereas water showed the lowest content among the six solvents. Generally, all the date seed cultivars contain high amounts of phenolic, flavonoid, and antioxidant activity. The carotenoid content was highest in the Barhi (1.98 mg/g DW) followed by Qatarah (1.25 mg/g DW) and Ruthana (0.89 mg/g DW) seed, while the anthocyanin content was highest in the Ruthana cultivar (5.51 ± 0.71 cyanidin 3-glucoside/g DM.) and lowest in Barhi date seed (3.335 ± 0.23 cyanidin 3-glucoside/g DM.). Among the three date seeds, the Ruthana seed showed the highest phenolic (93.36 ± 0.30 mg GAE/g) and flavonoid compounds (59.9 ± 0.44 mg CE/g), DPPH activity (78.6 ± 0.92%), and total reducing power (60.3 ± 0.09%). The optimum solvent for the extraction of the antioxidants and their activity in each date seed was validated by using partial least squares regression (PLS). The results revealed a variation in the valid and optimum extracts for each seed; 100% ethanol extract for Barhi seed and mixture of methanol:ethanol:water (M 40:E40:W20) extract for Ruthana and Qatarah cultivars were the best solvent systems. The high natural antioxidant content of date seeds indicates that they can be considered functional ingredients for food and medicinal uses. Full article
(This article belongs to the Special Issue Innovative Applications of Novel Natural Products in Medicinal and Agricultural Research)
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