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Advances in Research Related to Pharmacy and Food Technology

A special issue of Applied Sciences (ISSN 2076-3417). This special issue belongs to the section "Applied Biosciences and Bioengineering".

Deadline for manuscript submissions: closed (31 August 2024) | Viewed by 1079

Special Issue Editors


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Guest Editor
Departamento de Ciencias de la Salud y Biomédicas, Universidad Loyola Andalucía, 41704 Dos Hermanas, Spain
Interests: emulsions; surfactants; proteins; food technology
Special Issues, Collections and Topics in MDPI journals

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Guest Editor
Departamento de Ciencias de la Salud y Biomédicas, Universidad Loyola Andalucía, 41704 Dos Hermanas, Spain
Interests: metabolomics; bioactive compounds; mass spectrometry; chromatography

Special Issue Information

Dear Colleagues,

In the landscape of healthcare and nutrition, the intersection of pharmacy and food technology stands at the forefront of scientific innovation. The symbiotic relationship between these two disciplines has given rise to a myriad of advances that hold promise for revolutionizing the way we approach health and well-being. The constant evolution of pharmaceutical and food technologies has not only transformed the development and delivery of medicinal compounds but has also redefined our understanding of nutrition and its impact on human health.

In this exploration of the recent advances in research related to pharmacy and food technology, we delve into the cutting-edge discoveries that are reshaping the landscape of healthcare, nutrition, and the intricate relationship between what we consume and how it impacts our bodies.

This upcoming Special Issue in Applied Sciences will focus on novel methodologies applied to pharmacy and food technology, such as advances in the field of encapsulation of bioactive compounds, drug delivery, and the design of new food products. We would like to invite you to submit or recommend original research papers for this Special Issue “Advances in Research Related to Pharmacy and Food Technology”.

Prof. Dr. Jenifer Santos García
Dr. Elena Hurtado Fernández
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Applied Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • pharmacy
  • food technology
  • healthcare
  • nutrition

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Published Papers (1 paper)

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Research

15 pages, 2600 KiB  
Article
Simvastatin and Captopril Combined Transdermal Delivery System for Controlling Blood Pressure and Fat: Design, Characterization, and In Vivo Pharmacokinetic Evaluation
by Ya-Jing Ni, Run-Jia Wang, Zhao Liu, Li-Hui Xiao and Yan-Qiang Liu
Appl. Sci. 2024, 14(19), 9092; https://doi.org/10.3390/app14199092 - 8 Oct 2024
Viewed by 695
Abstract
We developed a sustained-release transdermal drug delivery system (TDDS) containing simvastatin (SIM) and captopril (CAP) to treat hypertension and hyperlipidemia and overcome treatment drawbacks, including significant liver first-pass effects, low bioavailability, and the short half-life of SIM and CAP oral tablets. We used [...] Read more.
We developed a sustained-release transdermal drug delivery system (TDDS) containing simvastatin (SIM) and captopril (CAP) to treat hypertension and hyperlipidemia and overcome treatment drawbacks, including significant liver first-pass effects, low bioavailability, and the short half-life of SIM and CAP oral tablets. We used a transdermal diffusion meter to preselect the formula of the SIM-CAP TDDS. Based on in vitro permeation experiments, we optimized the formula of the SIM-CAP TDDS to include 24% SIM, 24% CAP, 34% polyvinyl alcohol (PVA), 16% oleic acid (OA)–azone, and 2% polyacrylic acid resin II. We evaluated the optimized SIM-CAP TDDS formula by its appearance, stability, stickiness, drug content, in vivo pharmacokinetics, and skin irritation tests. The results indicated that the patch had good stability and stickiness. The SIM and CAP contents were 5.02 ± 0.41 mg/cm2 in the 1 cm2 SIM-CAP TDDS. The pharmacokinetic results indicated that the system continuously released SIM and CAP for 24 h and significantly enhanced their bioavailability, with a higher area under the curve. The SIM-CAP TDDS exhibits a sustained-release effect with good characteristics and pharmacokinetics. And it is safe and has no irritating effects on the skin; therefore, it is an ideal formulation. Full article
(This article belongs to the Special Issue Advances in Research Related to Pharmacy and Food Technology)
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