Recent Progress in Biomimetic Membranes
A special issue of Applied Sciences (ISSN 2076-3417). This special issue belongs to the section "Applied Biosciences and Bioengineering".
Deadline for manuscript submissions: closed (31 July 2021) | Viewed by 12014
Special Issue Editor
Special Issue Information
Dear Colleagues,
The bilayer lipid membrane is one of the essential constituents of the living cell. Many important proteins are incorporated or attached to it, their function closely depending on their electrical and other properties including fluidity. However, the investigation of these membrane proteins in their natural environment, for example in mitochondria or chloroplasts, is often hampered because the membranes are tightly packed with different proteins interacting with each other. Therefore, with the isolation and in vitro preparation of membrane proteins, artificial bilayer lipid membrane systems were sought early on, starting with the black bilayer lipid membrane (BLM), followed by BLMs tethered to surfaces, using, for example, peptide or oligoethylene tether groups or BLMS attached to polymer cushions, for example, block copolymers. The specifications of these systems include high electrical (gigaohm) resistance of the lipid membrane, mechanical robustness, fluidity, and aqueous layers accessible from both sides of the lipid membrane. The ultimate test is the demonstration of the function of a membrane protein in the artificial environment opening new methods of investigation for this important group of proteins.
Dr. Renate L. C. Naumann
Guest Editor
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Keywords
- bilayer lipdi membrane
- arificial lipid membrane
- biomimetic lipid membrane
- membrane proteins
- surface-attached lipid membranes
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