Regenerative Technologies in Plastic and Reconstructive Surgery

A special issue of Bioengineering (ISSN 2306-5354). This special issue belongs to the section "Regenerative Engineering".

Deadline for manuscript submissions: 31 December 2024 | Viewed by 1103

Special Issue Editors


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Guest Editor
Plastic and Reconstructive Surgery Department, Mayo Clinic Scottsdale-Phoenix, Scottsdale, AZ, USA
Interests: reconstructive surgery; burns; facial injury; skin cancer

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Guest Editor
Department of Plastic-, Reconstructive- and Hand Surgery, Utrecht University Medical Center, Utrecht University, Utrecht, The Netherlands
Interests: mesenchymal stem cells; fat grafting; regenerative surgery; extracellular matrix; hydrogel; plastic surgery

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Guest Editor
Human Histology & Embryology Section, Department of Surgery, Dentistry, Paediatrics & Gynaecology, University of Verona Medical School, 37134 Verona, Italy
Interests: tissue engineering; tissue regeneration; skin; vessels; biomaterials; silk fibroin; exosomes; Alzheimer’s disease; astrocytes; neuroinflammation

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Guest Editor
Department of Clinical Sciences, Sapienza University of Rome, 00185 Roma, Italy
Interests: dermatology; aesthetic medicine; skin; atopic dermatitis; psoriasis; melanoma; non melanoma skin cancers; lasers; phototherapy

Special Issue Information

Dear Colleagues,

Technological innovations in biotechnology and biomaterials have advanced rapidly over the years, which drive innovative solutions for tissue regeneration in plastic and reconstructive surgery. In recent years, regenerative technologies have emerged as a promising approach in the field, offering new possibilities for tissue repair, regeneration, and reconstruction.

Our journal is excited to announce a Special Issue dedicated to exploring the latest advancements in regenerative technologies in plastic and reconstructive surgery. Regenerative technologies offer a unique opportunity to harness the body's own regenerative capacity to repair and regenerate damaged tissues, providing more natural and sustainable solutions for patients. From stem cell therapy and tissue engineering to 3D bioprinting and regenerative medicine, researchers and clinicians are exploring a wide range of regenerative approaches to address complex challenges in plastic and reconstructive surgery.

This Special Issue will feature original research, review articles, and perspectives from leading experts in the field, covering a variety of topics related to regenerative technologies in plastic and reconstructive surgery. We encourage researchers, surgeons, and healthcare professionals to submit their work to this Special Issue. We look forward to exploring novel regenerative strategies and presenting groundbreaking advancements that have the potential to transform the current practices in the field.

Dr. Alanna M. Rebecca
Dr. Joris A. van Dongen
Prof. Dr. Ubaldo Armato
Dr. Steven Paul Nistico
Guest Editors

Manuscript Submission Information

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Keywords

  • plastic surgery
  • reconstructive surgery
  • tissue engineering
  • burn reconstruction
  • biomaterials
  • 3D bioprinting
  • regenerative medicine

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Published Papers (1 paper)

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Research

19 pages, 4062 KiB  
Article
Investigation of the Effect of High Shear Stress on Mesenchymal Stem Cells Using a Rotational Rheometer in a Small-Angle Cone–Plate Configuration
by Mario Mand, Olga Hahn, Juliane Meyer, Kirsten Peters and Hermann Seitz
Bioengineering 2024, 11(10), 1011; https://doi.org/10.3390/bioengineering11101011 - 11 Oct 2024
Viewed by 763
Abstract
Within the healthy human body, cells reside within the physiological environment of a tissue compound. Here, they are subject to constant low levels of mechanical stress that can influence the growth and differentiation of the cells. The liposuction of adipose tissue and the [...] Read more.
Within the healthy human body, cells reside within the physiological environment of a tissue compound. Here, they are subject to constant low levels of mechanical stress that can influence the growth and differentiation of the cells. The liposuction of adipose tissue and the subsequent isolation of mesenchymal stem/stromal cells (MSCs), for example, are procedures that induce a high level of mechanical shear stress. As MSCs play a central role in tissue regeneration by migrating into regenerating areas and driving regeneration through proliferation and tissue-specific differentiation, they are increasingly used in therapeutic applications. Consequently, there is a strong interest in investigating the effects of shear stress on MSCs. In this study, we present a set-up for applying high shear rates to cells based on a rotational rheometer with a small-angle cone–plate configuration. This set-up was used to investigate the effect of various shear stresses on human adipose-derived MSCs in suspension. The results of the study show that the viability of the cells remained unaffected up to 18.38 Pa for an exposure time of 5 min. However, it was observed that intense shear stress damaged the cells, with longer treatment durations increasing the percentage of cell debris. Full article
(This article belongs to the Special Issue Regenerative Technologies in Plastic and Reconstructive Surgery)
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