Fabrication of Biomaterials to Develop Tissue Engineering Scaffolds and Medical Devices

A special issue of Bioengineering (ISSN 2306-5354). This special issue belongs to the section "Nanobiotechnology and Biofabrication".

Deadline for manuscript submissions: 31 March 2025 | Viewed by 4095

Special Issue Editor


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Guest Editor
Institute of Nano Bio Convergence, Pusan National University, Busan 46241, South Korea
Interests: biomaterials; tissue engineering; multi-functional nanomaterials and nanocomposites; electrospun nanofiber mats; hydrogels; bioinks
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Special Issue Information

Dear Colleagues,

The efficient fabrication of biomaterials for tissue regeneration and medical device applications has a significant impact on today's healthcare technology.

The tunable physicochemical properties, mechanical strength, elasticity, and inexpensive preparation methods have allowed researchers working with polymers and nanomaterials to create a variety of inspiring biomaterial scaffolds like electrospun nanofiber, printable ink, and thin film, using the appropriate features. Using advanced biofabrication technologies, including bioprinting, the biomaterials are formulated into several biomedical devices, such as organ-on-a-chip devices, microsystems, biomimetic organoids, photobiomodulation patches, and smart medical devices. These fabricated biomedical devices exhibit remarkable cell–biomaterial interaction, cell biocompatibility, controlled drug delivery, biosensing, etc. They aim to improve tissue regeneration potential, thereby making a significant impact on healthcare technology.

This Special Issue aims to provide readers with an innovative platform to better understand the most recent research developments and challenges in preparing inspiring biomaterials for diverse biomaterial scaffolds and medical devices within the biomedical sector. Researchers are encouraged to influence this endeavor by contributing papers, reviews, or communications on this general subject.

Dr. Iruthaya Pandi Selestin Raja
Guest Editor

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Keywords

  • tissue engineering
  • biocompatible polymers
  • nanomaterials
  • biofabrication
  • bioprinting
  • photobiomodulation patches
  • smart medical devices
  • cell–biomaterial interaction

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Published Papers (1 paper)

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Review

13 pages, 5054 KiB  
Review
Nanofibrous Material-Reinforced Printable Ink for Enhanced Cell Proliferation and Tissue Regeneration
by Iruthayapandi Selestin Raja, Bongju Kim and Dong-Wook Han
Bioengineering 2024, 11(4), 363; https://doi.org/10.3390/bioengineering11040363 - 11 Apr 2024
Viewed by 1112
Abstract
The three-dimensional (3D) printing of biomaterials, cells, and bioactive components, including growth factors, has gained interest among researchers in the field of tissue engineering (TE) with the aim of developing many scaffolds to sustain size, shape fidelity, and structure and retain viable cells [...] Read more.
The three-dimensional (3D) printing of biomaterials, cells, and bioactive components, including growth factors, has gained interest among researchers in the field of tissue engineering (TE) with the aim of developing many scaffolds to sustain size, shape fidelity, and structure and retain viable cells inside a network. The biocompatible hydrogel employed in 3D printing should be soft enough to accommodate cell survival. At the same time, the gel should be mechanically strong to avoid the leakage of cells into the surrounding medium. Considering these basic criteria, researchers have developed nanocomposite-based printable inks with suitable mechanical and electroconductive properties. These nanomaterials, including carbon family nanomaterials, transition metal dichalcogenides, and polymeric nanoparticles, act as nanofillers and dissipate stress across polymeric networks through their electroactive interactions. Nanofiber-reinforced printable ink is one kind of nanocomposite-based ink that comprises dispersed nanofiber components in a hydrogel matrix. In this current review, we compile various TE applications of nanofiber-reinforced printable ink and describe the 3D-printing parameters, classification, and impact of cross-linkage. Furthermore, we discuss the challenges and future perspectives in this field. Full article
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