10th Anniversary of Bioengineering: Biosignal Processing

A special issue of Bioengineering (ISSN 2306-5354). This special issue belongs to the section "Biosignal Processing".

Deadline for manuscript submissions: 30 April 2025 | Viewed by 2877

Special Issue Editors


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Guest Editor
Department of Innovation Engineering (DII), University of Salento, Via Monteroni, 73100 Lecce, Italy
Interests: fault detection; sensor technologies; measurement techniques; monitoring and measurement systems; testing and characterization components; systems and monitoring equipment
Special Issues, Collections and Topics in MDPI journals

E-Mail Website
Guest Editor
Department of Electrical Engineering and Information Technology, University of Naples "Federico II", Naples, Italy
Interests: mathematical modeling; signal and image processing; radiomics; systems and synthetic biology; physiological control systems
Special Issues, Collections and Topics in MDPI journals

E-Mail Website
Guest Editor
Department of Innovation Engineering (DII), University of Salento, Via Monteroni, 73100 Lecce, Italy
Interests: biosignal processing; sensor technologies; measurement techniques; monitoring and measurement systems; medical diagnostics; systems and monitoring equipment

Special Issue Information

Dear Colleagues,

The field of bioengineering has come a long way since its inception, and one of the most significant advancements in recent years has been in the area of biosignal processing. Biosignal processing involves the acquisition, analysis, and interpretation of signals generated by the human body, such as electrocardiograms (ECGs), electroencephalograms (EEGs), and electromyograms (EMGs), among others.

Over the past decade, bioengineers have made remarkable progress in developing sophisticated algorithms and techniques to extract useful information from biosignals. These signals, once processed, can provide valuable insights into various physiological and pathological conditions, enabling early diagnosis, monitoring of diseases, and personalized treatment approaches. One major breakthrough in biosignal processing has been the development of advanced signal processing algorithms. These algorithms, often based on machine learning and artificial intelligence techniques, enable the extraction of valuable features from biosignals that are not easily discernible through conventional methods. For example, these algorithms can be used to identify specific patterns in an ECG that may indicate the presence of cardiac abnormalities. Additionally, bioengineers have been successful in developing non-invasive biosignal processing techniques. These techniques allow for the acquisition of biosignals without requiring invasive procedures or expensive medical equipment. For instance, wearable biosensors and mobile health applications have made it possible to continuously monitor biosignals, such as heart rate and sleep patterns, in real time and in everyday environments. Furthermore, the integration of biosignal processing with other fields, such as bioinformatics and genomics, has opened up new avenues for research and innovation. By combining biosignal data with genomic information, bioengineers can gain a deeper understanding of the relationship between genetic factors and physiological responses, leading to the development of personalized medicine strategies.

Looking ahead, the future of biosignal processing in bioengineering appears promising. Researchers are continuing to refine and improve existing algorithms, making them more accurate and robust.

Additionally, biosensors and wearable devices, along with measurement, instrumentation, sensing, and diagnostics of biosignals, are all aspects that play a crucial role in the analysis and interpretation of various biosignals that provide valuable information about a person's health status and can help in diagnosis, monitoring, healthcare assessments, early detection of diseases, and the development of personalized treatment strategies.

In conclusion, the 10th anniversary of bioengineering biosignal processing marks a significant milestone in the field's advancement. The progress made over the past decade has revolutionized healthcare by enabling the extraction of valuable information from biosignals. With further advancements on the horizon, biosignal processing will continue to play a crucial role in improving the diagnosis, treatment, and monitoring of diseases.

Dr. Andrea Cataldo
Prof. Dr. Francesco Amato
Dr. Raissa Schiavoni
Guest Editors

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Keywords

  • biosignal processing
  • signal analysis
  • biomedical devices
  • medical diagnostics
  • biomedical imaging
  • biomedical engineering
  • health monitoring
  • wearable systems
  • image processing and visualization
  • biosensor technology
  • biosensors
  • lab-on-chip and organ-on-a-chip instrumentation
  • smart sensing and predictive modeling
  • 4.0-ehanced biomedical systems

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Published Papers (2 papers)

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Research

12 pages, 1901 KiB  
Article
Visualized Lead Selection for Arrhythmia Classification Based on a Lead Activation Heatmap Using Multi-Lead ECGs
by Heng Wang, Tengqun Shen, Shoufen Jiang, Jilin Wang, Yijun Ma and Yatao Zhang
Bioengineering 2024, 11(6), 578; https://doi.org/10.3390/bioengineering11060578 - 7 Jun 2024
Viewed by 1003
Abstract
Visualizing the decision-making process is a key aspect of research regarding explainable arrhythmia recognition. This study proposed a visualized lead selection method to classify arrhythmia for multi-lead ECG signals. The proposed method has several advantages, as it uses a visualized approach to select [...] Read more.
Visualizing the decision-making process is a key aspect of research regarding explainable arrhythmia recognition. This study proposed a visualized lead selection method to classify arrhythmia for multi-lead ECG signals. The proposed method has several advantages, as it uses a visualized approach to select effective leads, avoiding redundant leads and invalid information. It also captures the temporal dependencies of ECG signals and the complementary information between leads. The method deployed a lead activation heatmap (LA heatmap) based on a lead-wise network to select the proper 5 leads from 12-lead ECG heartbeats extracted from the public 2018 Chinese Physiological Signal Challenge database (CPSC 2018 DB), which were then fed into a ResBiTime network combining bidirectional long short-term memory (Bi-LSTM) networks and residual connections for a classification task of nine heartbeat categories (i.e., N, AF, I-AVB, RBBB, PAC, PVC, STD, LBBB, and STE). The results indicate an average precision of 93.25%, an average recall of 93.03%, an average F1-score of 0.9313, and that the proposed method can effectively extract additional information from ECG heartbeat data. Full article
(This article belongs to the Special Issue 10th Anniversary of Bioengineering: Biosignal Processing)
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17 pages, 7422 KiB  
Article
Automatic Estimation of the Interference Subspace Dimension Threshold in the Subspace Projection Algorithms of Magnetoencephalography Based on Evoked State Data
by Ruochen Zhao, Ruonan Wang, Yang Gao and Xiaolin Ning
Bioengineering 2024, 11(5), 428; https://doi.org/10.3390/bioengineering11050428 - 26 Apr 2024
Viewed by 1209
Abstract
A class of algorithms based on subspace projection is widely used in the denoising of magnetoencephalography (MEG) signals. Setting the dimension of the interference (external) subspace matrix of these algorithms is the key to balancing the denoising effect and the degree of signal [...] Read more.
A class of algorithms based on subspace projection is widely used in the denoising of magnetoencephalography (MEG) signals. Setting the dimension of the interference (external) subspace matrix of these algorithms is the key to balancing the denoising effect and the degree of signal distortion. However, most current methods for estimating the dimension threshold rely on experience, such as observing the signal waveforms and spectrum, which may render the results too subjective and lacking in quantitative accuracy. Therefore, this study proposes a method to automatically estimate a suitable threshold. Time–frequency transformations are performed on the evoked state data to obtain the neural signal of interest and the noise signal in a specific time–frequency band, which are then used to construct the objective function describing the degree of noise suppression and signal distortion. The optimal value of the threshold in the selected range is obtained using the weighted-sum method. Our method was tested on two classical subspace projection algorithms using simulation and two sensory stimulation experiments. The thresholds estimated by the proposed method enabled the algorithms to achieve the best waveform recovery and source location error. Therefore, the threshold selected in this method enables subspace projection algorithms to achieve the best balance between noise removal and neural signal preservation in subsequent MEG analyses. Full article
(This article belongs to the Special Issue 10th Anniversary of Bioengineering: Biosignal Processing)
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