Innovations in Implantable Cardiac Devices: Design, Materials, and Performance

A special issue of Bioengineering (ISSN 2306-5354). This special issue belongs to the section "Biomedical Engineering and Biomaterials".

Deadline for manuscript submissions: 31 March 2025 | Viewed by 777

Special Issue Editors


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Guest Editor
Clinical Cardiac Electrophysiology, The Ohio State University Wexner Medical Center, Columbus, OK 43210, USA
Interests: clinical cardiac electrophysiology; cardiovascular disease; atrial fibrillation; catheter ablation; defibrillators; implantable; device removal; pacemaker; artificial; bradycardia; cardiac resynchronization therapy devices

E-Mail Website
Guest Editor
Cardiovascular Medicine, The Ohio State University Wexner Medical Center, Columbus, OK 43210, USA
Interests: clinical cardiac electrophysiology; cardiovascular disease; atrial fibrillation; catheter ablation; defibrillators; implantable; pacemaker; artificial; bradycardia; cardiac resynchronization therapy devices

E-Mail Website
Guest Editor
Clinical Cardiac Electrophysiology, The Ohio State University Wexner Medical Center, Columbus, OK 43210, USA
Interests: biomaterials; clinical engineering; biomedical devices; cardiovascular engineering; biomedical instrumentation; biomechanical engineering; biomedical modeling; biomedical technology
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

This Special Issue aims to provide a comprehensive overview of recent advancements in the field of implantable cardiac devices, with a specific focus on the designs, materials, and performances of these devices. Implantable cardiac devices, such as pacemakers-transvenous/leadless, defibrillators, and cardiac resynchronization therapy devices, play a crucial role in managing various heart conditions. The evolution of these devices is driven by continuous innovations in their designs and materials used, which collectively enhance their performance and patient outcomes. This issue will dig into the multidisciplinary approaches that contribute to the development of next-generation cardiac devices, highlighting cutting-edge research and emerging trends.

Key Research Topics:

  1. Advanced materials for cardiac device leads
  2. Advancement in leadless technologies and design
  3. Design improvements in cardiac leads
  4. Performance optimization in cardiac devices
  5. Technological integration in cardiac devices
  6. Clinical outcomes and case studies
  7. Regulatory and manufacturing considerations

Dr. Mahmoud M. Houmsse
Dr. Benjamin Buck
Dr. Anmar Salih
Guest Editors

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Keywords

  • cardiac devices
  • implantable leads
  • biocompatible materials
  • device design
  • lead performance
  • pacemakers
  • leadless pacemakers
  • defibrillators
  • cardiac resynchronization therapy
  • electrical performance
  • device durability
  • remote monitoring
  • clinical trials

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Published Papers (1 paper)

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Research

24 pages, 17252 KiB  
Article
3D-Printing of Artificial Aortic Heart Valve Using UV-Cured Silicone: Design and Performance Analysis
by Atila Ertas, Erik Farley-Talamantes, Olkan Cuvalci and Ozhan Gecgel
Bioengineering 2025, 12(1), 94; https://doi.org/10.3390/bioengineering12010094 - 20 Jan 2025
Viewed by 613
Abstract
The advancement of medical 3D printing technology includes several enhancements, such as decreasing the length of surgical procedures and minimizing anesthesia exposure, improving preoperative planning, creating personalized replicas of tissues and bones specific to individual patients, bioprinting, and providing alternatives to human organ [...] Read more.
The advancement of medical 3D printing technology includes several enhancements, such as decreasing the length of surgical procedures and minimizing anesthesia exposure, improving preoperative planning, creating personalized replicas of tissues and bones specific to individual patients, bioprinting, and providing alternatives to human organ transplants. The range of materials accessible for 3D printing within the healthcare industry is significantly narrower when compared with conventional manufacturing techniques. Liquid silicone rubber (LSR) is characterized by its remarkable stability, outstanding biocompatibility, and significant flexibility, thus presenting substantial opportunities for manufacturers of medical devices who are engaged in 3D printing. The main objective of this study is to develop, refine, and assess a 3D printer that can employ UV-cured silicone for the fabrication of aortic heart valves. Additionally, the research aims to produce a 3D-printed silicone aortic heart valve and evaluate the feasibility of the final product. A two-level ANOVA experimental design was utilized to investigate the impacts of print speed, nozzle temperature, and layer height on the print quality of the aortic heart valve. The findings demonstrated that the 3D-printed heart valve’s UV-cured silicone functioned efficiently, achieving the target flow rates of 5 L/min and 7 L/min. Two distinct leaflet thicknesses (LT) of the heart valve, namely 0.8 mm and 1.6 mm, were also analyzed to simulate calcium deposition on the leaflets. Full article
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