Search for Articles:
Title / Keyword
Author / Affiliation / Email
Journal
Article Type
 
 
Advanced Search
 
Section
Special Issue
Volume
Issue
Number
Page
 
4.0
3.8
Journals
Bioengineering
Special Issues
Functional Biomaterials for Regenerative Engineering
share announcement

Functional Biomaterials for Regenerative Engineering

A special issue of Bioengineering (ISSN 2306-5354).

Deadline for manuscript submissions: closed (15 July 2018) | Viewed by 12746

Special Issue Editor

Dr. Gulden Camci-Unal

E-Mail Website
Guest Editor
Department of Chemical Engineering, University of Massachusetts Lowell, Lowell, MA 01854, USA
Interests: biomaterials; tissue engineering; cardiovascular diseases; biomineralization; wound healing; additive manufacturing; point of care diagnostics
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear colleagues,

Every year millions of people suffer from the effects of disease or degeneration in tissues and organs. Due to the limited number of organ donors, there has been an increasing need for tissue-engineered constructs or strategies to induce regenerative repair after injury (e.g., heart, blood vessels, liver, lung, bone, cartilage, kidney). The ultimate goal of regenerative engineering is to repair or replace damaged tissues by converging the principles from developmental biology, stem cell biology, materials science, engineering, and medicine. In this context, biomaterial-based approaches are promising strategies. A key enabling technology for these approaches is the development of functional biomaterials containing instructive signals to modulate cell behavior.

Hydrogel-based biomaterials have been widely used in tissue engineering and regenerative medicine research, particularly to facilitate cell-cell and cell- biomaterial interactions in a controlled manner. In this Special Issue, we will include example papers for hydrogel-based biomaterials. We will also cover a wider range of biomaterial variants (e.g., porous scaffolds, nano- and micro-particles, synthetic or naturally derived polymers, proteins, carbohydrates, lipids) that highlight research results from basic science to clinical applications. This issue will also highlight the applications of these biomaterial technologies to create instructive microenvironments to control cell fate such as self-renewal, quiescence and differentiation. In addition, microfabrication techniques for regenerative engineering, such as implementation of microfluidic tools and bioprinting approaches will also be covered in this Special Issue.

Dr. Gulden Camci-Unal

Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Bioengineering is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Benefits of Publishing in a Special Issue

  • Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
  • Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
  • Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
  • External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
  • e-Book format: Special Issues with more than 10 articles can be published as dedicated e-books, ensuring wide and rapid dissemination.

Further information on MDPI's Special Issue polices can be found here.

Published Papers (2 papers)

Download All Papers
Order results
Result details
Show export options expand_more Show export options expand_less
Select all
Export citation of selected articles as:

Research

Jump to: Review

13 pages, 7637 KiB  
Article
Microfabricated and 3-D Printed Soft Bioelectronic Constructs from PAn-PAAMPSA-Containing Hydrogels
by John R. Aggas, Sara Abasi, Blake Smith, Michael Zimmerman, Michael Deprest and Anthony Guiseppi-Elie
Bioengineering 2018, 5(4), 87; https://doi.org/10.3390/bioengineering5040087 - 17 Oct 2018
Cited by 13 | Viewed by 6249
Abstract
The formation of hybrid bioactive and inherently conductive constructs of composites formed from polyaniline-polyacrylamidomethylpropane sulfonic acid (PAn-PAAMPSA) nanomaterials (0.00–10.0 wt%) within poly(2-hydroxy ethyl methacrylate-co-N-{Tris(hydroxymethyl)methyl} acrylamide)-co-polyethyleneglycol methacrylate) p(HEMA-co-HMMA-co-PEGMA) hydrogels was made possible using microlithographic fabrication and [...] Read more.
The formation of hybrid bioactive and inherently conductive constructs of composites formed from polyaniline-polyacrylamidomethylpropane sulfonic acid (PAn-PAAMPSA) nanomaterials (0.00–10.0 wt%) within poly(2-hydroxy ethyl methacrylate-co-N-{Tris(hydroxymethyl)methyl} acrylamide)-co-polyethyleneglycol methacrylate) p(HEMA-co-HMMA-co-PEGMA) hydrogels was made possible using microlithographic fabrication and 3-D printing. Hybrid constructs formed by combining a non-conductive base (0.00 wt% PAn-PAAMPSA) and electroconductive (ECH) (varying wt% PAn-PAAMPSA) hydrogels using these two production techniques were directly compared. Hydrogels were electrically characterized using two-point probe resistivity and electrochemical impedance spectroscopy. Results show that incorporation of >0.10 wt% PAn-PAAMPSA within the base hydrogel matrices was enough to achieve percolation and high conductivity with a membrane resistance (RM) of 2140 Ω and 87.9 Ω for base (0.00 wt%) and ECH (10.0 wt%), respectively. UV-vis spectroscopy of electroconductive hydrogels indicated a bandgap of 2.8 eV that was measurable at concentrations of >0.10 wt% PAn-PAAMPSA. Both base and electroconductive hydrogels supported the attachment and growth of NIH/3T3 fibroblast cells. When the base hydrogel was rendered bioactive by the inclusion of collagen (>200 µg/mL), it also supported the attachment, but not the differentiation, of PC-12 neural progenitor cells. Full article
(This article belongs to the Special Issue Functional Biomaterials for Regenerative Engineering)
►▼ Show Figures

Graphical abstract

Review

Jump to: Research

8 pages, 2563 KiB  
Review
Non-Transfusional Hemocomponents: From Biology to the Clinic—A Literature Review
by Roberta Gasparro, Erda Qorri, Alessandra Valletta, Michele Masucci, Pasquale Sammartino, Alessandra Amato and Gaetano Marenzi
Bioengineering 2018, 5(2), 27; https://doi.org/10.3390/bioengineering5020027 - 31 Mar 2018
Cited by 20 | Viewed by 5644
Abstract
Non-transfusional hemocomponents for surgical use are autogenous products prepared through the centrifugation of a blood sample from a patient. Their potential beneficial outcomes include hard and soft tissue regeneration, local hemostasis, and the acceleration of wound healing. Therefore, they are suitable for application [...] Read more.
Non-transfusional hemocomponents for surgical use are autogenous products prepared through the centrifugation of a blood sample from a patient. Their potential beneficial outcomes include hard and soft tissue regeneration, local hemostasis, and the acceleration of wound healing. Therefore, they are suitable for application in different medical fields as therapeutic options and in surgical practices that require tissue regeneration. Full article
(This article belongs to the Special Issue Functional Biomaterials for Regenerative Engineering)
►▼ Show Figures

Figure 1

Show export options expand_more Show export options expand_less
Select all
Export citation of selected articles as:
 
Displaying articles 1-2
Back to TopTop