The Structure and Function of Membrane-Binding Peptides

A special issue of Biology (ISSN 2079-7737). This special issue belongs to the section "Biochemistry and Molecular Biology".

Deadline for manuscript submissions: 31 December 2024 | Viewed by 243

Special Issue Editor


E-Mail Website
Guest Editor
School of Systems Biology, George Mason University, Manassas, VA 20110, USA
Interests: simulation; molecular dynamics; bioinformatics; proteomics; modeling

Special Issue Information

Dear Colleagues,

There are several classes of peptides, including antimicrobial and cell-penetrating peptides, which are notable for their interactions with lipid bilayers. These peptides can exhibit drastic conformational changes as they transition from solution to bilayer environments, and their effects range from passive diffusion through the bilayer to large-scale bilayer perturbations, including the formation of pores and cell lysis. Due to these characteristics, membrane-binding peptides are increasingly being investigated for their relation to human disease and potential use as therapeutics.

We invite you to submit an article that furthers our understanding of the structure–function relationship of membrane-binding peptides. Ultimately, we seek articles that enrich our understanding of the underlying physicochemical mechanisms of action of these peptides through experimental or molecular simulations. In this Special Issue, we welcome original research articles and reviews.

I look forward to receiving your contributions.

Dr. Christopher Lockhart
Guest Editor

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Keywords

  • membrane-active peptides
  • antimicrobial peptides
  • cell-penetrating peptides
  • peptide–lipid interactions
  • peptides
  • lipid bilayers

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Published Papers

This special issue is now open for submission.
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