Inflammation in Cancer: A Target for Prevention and Therapy 2.0

A special issue of Biology (ISSN 2079-7737). This special issue belongs to the section "Cell Biology".

Deadline for manuscript submissions: closed (30 November 2023) | Viewed by 508

Special Issue Editors


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Guest Editor
Department of Biotechnology, Chemistry and Pharmacy, University of Siena, 53100 Siena, SI, Italy
Interests: pharmacological characterization of new antitumoral drugs of chemical or natural origin; inflammation and cancer; role of prostaglandins in tumor progression and angiogenesis; tyrosine kinase receptor activity in tumor progression and angiogenesis; characterization of novel molecules with pro- and anti-angiogenic activity; molecular mechanisms underlying CCM pathogenesis; physio-pathological functions of KRIT1 protein and its signaling pathways
Special Issues, Collections and Topics in MDPI journals

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Guest Editor
Department of Pharmaceutical Sciences, University of Pavia, 27100 Pavia, PV, Italy
Interests: inflammatory disorders, breast cancer, and cancer-related-inflammation; preclinical and translational studies aimed at characterizing the role of NAD metabolism in the progression of cancer and inflammatory bowel disorders (IBD), in particular in studing the pathogenesis and progression of IBD and breast cancer at the molecular level; role of iNAMPT/eNAMPT in the progression and/or pathogenesis of breast cancer and IBD; pharmacological inhibition of the extracellular form of NAMPT (eNAMPT) using monoclonal antibodies in inflammatory disorders and cancer; pharmacological characterization of new antitumoral drugs (e.g., IDO inhibitors) of chemical origin and novel neutralizing antibodies; characterization of novel molecules as a drug with anti-inflammatory activity; study of novel biomarkers for clinical prediction of biological drug responses
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Special Issue Information

Dear Colleagues,

This collection is the second edition of the previous one, "Inflammation in Cancer: A Target for Prevention and Therapy".

Chronic inflammation is a critical component of tumor progression and pathogenesis. Several inflammatory diseases increase the risk of cancer, and moreover, the activation of a pathway promoting inflammatory cytokine production and inflammatory cell recruitment is observed in tumors that are not directly related to an inflammatory condition.

Several questions related to the role of inflammation in molecular mechanisms and in tumor development are still unresolved.

In this Special issue, we aim to produce a collection of the latest progress associated with the role of inflammatory pathways in the development and progression of different tumors. Findings should provide insights into how inflammation can influence cell transformation, tumor formation, and metastasis and elucidate the therapeutic implications and effects given by modulating inflammatory signaling pathways.

Dr. Federica Finetti
Dr. Lorenza Trabalzini
Dr. Cristina Travelli
Guest Editors

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Keywords

  • inflammation
  • cyclooxygenase 2
  • microsomal prostaglandin E synthase 1
  • cancer
  • epithelial mesenchymal transition
  • biomarkers
  • immunotherapy
  • metabolism
  • myeloid and lymphoid cells

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