Spinal Cord Compression: Molecular, Cellular and Therapeutic Aspects
A special issue of Biomedicines (ISSN 2227-9059). This special issue belongs to the section "Neurobiology and Clinical Neuroscience".
Deadline for manuscript submissions: closed (31 July 2024) | Viewed by 1635
Special Issue Editor
Interests: spinal cord injury; neuroprotection; extracellular vesicles; phytomedicine; regenerative medicine; post-operative pain
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Spinal cord compression could result from both atraumatic and traumatic causes. Despite the protection from the spinal vertebra, occasionally, the spinal cord is faced with an assortment of compressive forces that are caused by blood clots, neoplastic growth, infections, ectopic bone growth, or the protrusion of intervertebral discs within the restricted area of the spinal epidural space and meninges. A more drastic compression force comes from falls, traffic accidents, sports injuries, etc. To date, the only available therapy has involved drastic surgery and the systematic use of drugs, and surgery was only aided by medical examinations rather than images. The molecular and cellular study of spinal cord compression would benefit from the identification of biomarkers, which could be used as a diagnostic indication and/or a drug target for new therapies.
Efforts have been made for the molecular and cellular phenotypes of some spinal cord compression injuries, for example, cervical spondylotic myelopathy. This is the most common cause of spinal cord dysfunction, and its etiologies includes the formation of osteophytes, disc herniation, degenerative disc disease, ossification of the posterior longitudinal ligament, and pathology of ligamentum flavum. These eventually cause spinal cord compression. High-throughput methods, as well as structure-sensitive studies, have expanded our repertoire of potential biomarkers. This Special Issue of Biomedicines focuses on recent advances in the characterization of molecular and cellular events that are involved in spinal cord compression. These may provide valuable information for the diagnosis as well as treatment of the injury.
Dr. Meng-Jen Lee
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biomedicines is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- spinal cord compression
- neuroprotection
- axon regeneration
- targets
- oligodendrocytes
- macrophage
- extracellular vesicles
- phytomedicine
- stem cells
Benefits of Publishing in a Special Issue
- Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
- Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
- Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
- External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
- e-Book format: Special Issues with more than 10 articles can be published as dedicated e-books, ensuring wide and rapid dissemination.
Further information on MDPI's Special Issue polices can be found here.
