Immune Mechanisms in Dermatology
A special issue of Biomedicines (ISSN 2227-9059). This special issue belongs to the section "Immunology and Immunotherapy".
Deadline for manuscript submissions: 30 April 2025 | Viewed by 229
Special Issue Editor
Interests: skin cancer; dermoscopy; melanom; psoriasis; connective tissue diseases; venereology
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
As the largest human organ, the skin performs multiple functions to protect the DNA of every cell. In 2024, the complex immunological mechanisms are becoming increasingly deeply understood.
Significant progress has been made in understanding and describing innate and acquired immunity, from (mostly epidermal) skin carcinogenesis to STDs. We now define melanoma as “a genetic and immunological tumor” and use direct immunological therapies in the metastatic form that were not imagined a few decades ago.
We develop local therapies based on Toll-like receptor (TLR) modulators, as these factors of innate immunity are well-understood in the signaling cascade from cutaneous viral infections (including DNA) to skin carcinomas. We correlate the presence of basal cell carcinoma with decreased immunity of the individual as we assess the signaling function of the skin.
We understand the superior acantholysis and apoptolysis in pemphigus and are more confident in the diagnosis when we corroborate histopathological examination with DIF and IIF. We treat urticaria with biologicals against IgE and psoriasis with biologicals against activated interleukins. We use PRP therapy in various conditions with promising results.
The aim of this issue of the prestigious journal Biomedicines is to publish quality research that pushes forward the field of knowledge in dermatological immunology.
Dr. Olga Simionescu
Guest Editor
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Keywords
- skin innate immunity
- skin acquired immunity
- biologics
- immunofluorescence
- PRP
- viral skin infections
- bullous disorders
- connective tissue disorders
- skin cancer immunology
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