Advances in Head and Neck Cancer

A special issue of Biomedicines (ISSN 2227-9059). This special issue belongs to the section "Molecular and Translational Medicine".

Deadline for manuscript submissions: 31 March 2025 | Viewed by 456

Special Issue Editors


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Guest Editor
Department of Radiation Oncology & Proton and Radiation Therapy Center, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Kaohsiung 833, Taiwan
Interests: radiotherapy; proton beam therapy; physiological signal analysis; nasopharyngeal carcinoma; head and neck cancer; brain tumor; esophageal cancer; thoracic tumor; pediatric cancer
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Guest Editor
Department of Otolaryngology, Kaohsiung Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Kaohsiung 833, Taiwan
Interests: nasopharyngeal carcinoma; head and neck cancer; cancer survivorship; sinonasal cancer; skull base surgery
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

This Special Issue, "Advances in Head and Neck Cancer", will provide a thorough exploration of the latest developments in the diagnosis, treatment, and comprehensive management of head and neck cancers. This Special Issue will delve into innovative therapeutic approaches, such as personalized medicine, immunotherapy, and novel molecular targets, with a special emphasis on advanced radiotherapy techniques, including dose escalation, dose de-escalation, VMAT, SBRT, image guidance, and particle therapy, as well as the incorporation of minimally invasive surgical methods.

In addition to innovative treatments, this Special Issue will focus on the use of biomarkers to predict treatment responses and understand disease progression.

By featuring a diverse range of expert perspectives, this Special Issue will provide invaluable insights for clinicians, researchers, and healthcare professionals committed to advancing treatment outcomes and comprehensive care for patients with head and neck cancer.

Dr. Yu-Ming Wang
Dr. Sheng-Dean Luo
Guest Editors

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Keywords

  • modern therapeutic approach
  • nasopharyngeal carcinoma
  • head and neck cancer
  • particle therapy
  • cancer survivorship
  • sinonasal cancer

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Published Papers (1 paper)

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Research

11 pages, 1160 KiB  
Article
Risk Factors for Unplanned Emergency Department Visits in Patients with Nasopharyngeal Carcinoma During Radiotherapy
by Wei-Shan Chen, Chien-Lin Lee, Wei-Chih Chen, Ching-Nung Wu, Tai-Jan Chiu, Yao-Hsu Yang, Hao-Wei Lu, Sheng-Dean Luo and Yu-Ming Wang
Biomedicines 2024, 12(11), 2616; https://doi.org/10.3390/biomedicines12112616 - 15 Nov 2024
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Abstract
Background/Objectives: Nasopharyngeal carcinoma (NPC) is commonly treated with radiotherapy (RT) or concurrent chemoradiotherapy (CCRT). However, unplanned emergency department (ED) visits during treatment can disrupt therapy and impact patient outcomes. This study aims to identify the risk factors associated with unplanned ED visits in [...] Read more.
Background/Objectives: Nasopharyngeal carcinoma (NPC) is commonly treated with radiotherapy (RT) or concurrent chemoradiotherapy (CCRT). However, unplanned emergency department (ED) visits during treatment can disrupt therapy and impact patient outcomes. This study aims to identify the risk factors associated with unplanned ED visits in patients with NPC receiving RT or CCRT. Methods: We retrospectively analyzed 2111 patients with NPC treated between 2001 and 2019 at Chang Gung Memorial Hospital. Patients were categorized based on whether they experienced an unplanned ED visit during or up to three months post-treatment. Demographic and clinical variables were compared using the Chi-squared test, and survival outcomes were assessed using Kaplan-Meier analysis. Results: Among the cohort, 573 patients (27.2%) experienced at least 1 unplanned ED visit. Risk factors for unplanned ED visits included older age (p < 0.001), hypertension (p < 0.001), higher Charlson Comorbidity Index (p = 0.001), and advanced clinical stage (T stage, p = 0.0046; N stage, p = 0.0034; M stage, p = 0.0008). No significant difference in ED visit rates was observed between RT alone and CCRT groups. Conclusions: Unplanned ED visits were common during NPC treatment, with risk factors primarily related to patient age, comorbidities, and disease stage. Identifying high-risk patients may enable interventions to reduce ED visits, improve survival outcomes, and alleviate healthcare costs. Full article
(This article belongs to the Special Issue Advances in Head and Neck Cancer)
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