Extracellular Matrix in Health and Disorders
A special issue of Biomedicines (ISSN 2227-9059). This special issue belongs to the section "Molecular and Translational Medicine".
Deadline for manuscript submissions: 30 November 2024 | Viewed by 1848
Special Issue Editor
Special Issue Information
Dear Colleagues,
The extracellular matrix (ECM) is a complex structure composed of proteins, glycoproteins, and proteoglycans in different percentages. This variability provides different functional and structural features to many tissues (dermis, bone, tendon, etc.), making the ECM a key point for tissue specialization and physiological processes.
Changes in protein composition and structure, as well as the structural modification of the ECM itself, lead to tissue dysfunctionality, such as photoaging and inadequate matrix repair, and diseases, such as osteoporosis.
Research aimed at clarifying the ECM’s role and qualities is essential for identifying specific targets, designing efficient drugs, and setting clinical strategies able to counter the features of pathological tissues.
This Special Issue aims to collect novel insights into the ECM’s involvement in the normal and altered physiological processes of the skin/dermis, bone, tendon, and other connective tissues.
We are interested in submissions of original research and reviews focusing on the in vivo and ex vivo characterization of the ECM in healthy and pathological tissues, with particular attention paid to structural analyses and advances in imaging, as well as in vitro studies and models, able to increase our knowledge concerning the ECM.
Dr. Caterina Licini
Guest Editor
Manuscript Submission Information
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Keywords
- ECM
- connective tissue
- healthy tissues
- pathological tissues
- imaging
- drug targets
- markers
- dermis
- bone
- tendon
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