Advanced Research of Cartilage Repair and Regeneration
A special issue of Biomedicines (ISSN 2227-9059). This special issue belongs to the section "Molecular and Translational Medicine".
Deadline for manuscript submissions: closed (31 May 2023) | Viewed by 1949
Special Issue Editor
Special Issue Information
Dear Colleagues,
Arthritis is the most common cause of disability, the most common form of which is osteoarthritis (OA). Early OA is treated with joint-preserving interventions such as lifestyle modification, pharmaceuticals, and surgery. The most commonly used surgical modalities for the treatment of localized cartilage lesions in early OA are microfracture, mosaicplasty (osteochondral autograft), and autologous chondrocyte implantation. These therapies may restore function and relieve pain for a short period, but they are not able to arrest or delay disease progression. End-stage OA is treated with joint replacement; however, the functional outcomes can be poor and the lifespan of prostheses is limited. New strategies based on mesenchymal stem cells are being actively tested in humans and animals; however, few have been successfully translated into clinical practice. This Special Issue on Advanced Research of Cartilage Repair and Regeneration invites original and review articles focusing on stem cells, scaffold, and chondrogenic factors as well as their combinations for articular cartilage regeneration and repair. In vivo animal studies with long-term (24 months and beyond) follow-up are particularly welcome.
Prof. Dr. Zongbing You
Guest Editor
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Keywords
- articular cartilage
- stem cells
- scaffold
- chondrogenic factor
- cartilage repair
- cartilage regeneration
- regenerative medicine
- tissue engineering
- chondrocytes
- articular joint
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