Pharmacology of Cardiovascular Diseases
A special issue of Biomolecules (ISSN 2218-273X).
Deadline for manuscript submissions: 31 May 2025 | Viewed by 149
Special Issue Editors
Interests: cardioprotection; ischemia–reperfusion; heme oxygenase-1; autophagy; natural antioxidants
Special Issues, Collections and Topics in MDPI journals
Interests: cardioprotection; ischemia–reperfusion; heme oxygenase-1; autophagy; natural antioxidants
Interests: cardioprotection; ischemia–reperfusion; heme oxygenase-1; autophagy; natural antioxidants
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Cardiovascular diseases (CVDs) are the leading cause of death worldwide, responsible for millions of deaths annually. Understanding these diseases’ pathophysiology is essential to develop new pharmacological treatments that reduce mortality and improve the quality of life. Pharmacological research allows for the discovery of new drugs or the improvement of existing therapies. Oxidative stress is a key factor in the development of CVDs, including ischemia–reperfusion or heart failure. Modulating the redox balance could alter the stress response of the myocardium, including autophagy. The latter is generally protective in the cardiovascular system, helping to remove damaged proteins and organelles, such as dysfunctional mitochondria, which can contribute to heart failure, atherosclerosis, and other CVDs. However, in some cases, excessive or dysregulated autophagy can lead to cell death, contributing to cardiac dysfunction. For instance, in conditions like ischemia–reperfusion injury, overactive autophagy can exacerbate cardiac damage. The pharmacological modulation of redox balance and/or autophagy may help combat CVDs.
In this Special Issue, original research articles, clinical studies, and reviews are welcome on recent advancements in drug therapy related to cardiovascular pharmacology, giving special attention to redox balance and autophagy. We look forward to receiving your contributions.
Dr. Istvan Lekli
Dr. Alexandra Gyongyosi
Dr. Istvan Bak
Guest Editors
Manuscript Submission Information
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Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- cardioprotection autophagy
- redox balance
- heart faliure
- cardiovascular pharmacotherapy
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