Special Issues

Biomolecules publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue polices and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Nitrogen Signaling, Transport, and Function in Plants
edited by
submission deadline 20 Nov 2024 | 5 articles | Viewed by 18041
Keywords: nitrogen assimilation; nitrogen sensing; nitrogen transport; nitrogen signaling; primary nitrate response; systemic nitrogen signaling
(This special issue belongs to the Section Biological Factors)
Heart Diseases: Molecular Mechanisms and New Therapies
edited by Glen Pyle
submission deadline 20 Nov 2024 | 2 articles | Viewed by 2849
Keywords: heart failure; heart disease; myocardial; molecular mechanisms; therapies
(This special issue belongs to the Section Molecular Medicine)
State-of-the-Art Cardio-Oncology
edited by
submission deadline 20 Nov 2024 | 1 articles | Viewed by 829
(This special issue belongs to the Section Chemical Biology)
Role of Iron Dysregulation in Chronic Inflammatory Diseases and Their Complications
edited by
submission deadline 20 Nov 2024 | Viewed by 535
Keywords: iron; oxidative stress; ferroptosis; inflammation; chronic disease; metabolism; mitochondrial dysfunction
(This special issue belongs to the Section Molecular Medicine)
Experimental and Theoretical Approaches to Protein-Targeting Drug Discovery: 2nd Edition submission deadline 29 Nov 2024 | 2 articles | Viewed by 3548 | Submission Open
Keywords: proteins; peptides; amyloid; aptamers; molecular docking; Alzheimer disease; Parkinson’ s disease; neurodrugs; biotechnological enzymes; antiviral drugs; vaccines; biomolecular targets; COVID-19; SARS-CoV-2; spike protein; peptide aggregation; drug repurposing; natural products; synthetic antivirals; anticancer therapeutics
(This special issue belongs to the Section Chemical Biology)
State-of-the-Art Biophysics, Biochemistry and Molecular Biology in China submission deadline 30 Nov 2024 | 17 articles | Viewed by 50012 | Submission Open
Keywords: Molecular modelling; molecular dynamics simulation; protein-protein interaction; protein folding; Bioinformatics; molecular docking; drug design; bio-nanomaterial interface; molecular machine; functional biomacromolecule design and optimization; functional regulation of RNA/DNA; microbiota; multimodal data; machine learning; vaccines
(This special issue belongs to the Section Molecular Biophysics)
Biomolecular Approaches and Drugs for Neurodegeneration submission deadline 30 Nov 2024 | 8 articles | Viewed by 17596 | Submission Open
Keywords: proteins; peptides; amyloid; Alzheimer disease; Parkinson’ s disease; neurodrugs; G-quadruplex nucleic acids; biotechnology; biomolecular targets; peptide aggregation; natural products; synthetic drugs; antiamyloid therapeutics; machine learning
(This special issue belongs to the Section Chemical Biology)
Unraveling Mysteries of Heme Metabolism submission deadline 30 Nov 2024 | 8 articles | Viewed by 17520 | Submission Open
Keywords: heme synthesis; heme metabolism; metabolic disorders; tetrapyrroles; heme proteins
(This special issue belongs to the Section Molecular Biology)
Molecular and Cellular Basis for Rare Genetic Diseases submission deadline 30 Nov 2024 | 5 articles | Viewed by 14191 | Submission Open
Keywords: neurodevelopment; intellectual disability; neurodegeneration; rare genetic diseases; systems biology; membrane trafficking; epigenetics; metabolism
(This special issue belongs to the Section Cellular Biochemistry)
Dysregulation of Calcium Signaling in Pathological Processes
edited by
submission deadline 30 Nov 2024 | 5 articles | Viewed by 11296 | Submission Open
Keywords: Ca2+-ATPases; calmodulinopathies; cancer; cardiovascular diseases; channelopathies; endocrine diseases; mitochondrial diseases; muscle diseases; neurodegenerative diseases; troponin C
(This special issue belongs to the Section Molecular Medicine)
Brain Sterols: Biosynthesis and Physiology in Health and Disease submission deadline 30 Nov 2024 | 4 articles | Viewed by 10989 | Submission Open
Keywords: sterol biosynthesis; sterol turnover; oxysterol; brain; cholesterol; development; aging; medication side effects; inborn errors of sterol biosynthesis; DHCR7
(This special issue belongs to the Section Synthetic Biology and Bioengineering)
Molecular Mechanisms of Alpha-Synuclein in Parkinson's Disease and Other Synucleinopathies submission deadline 30 Nov 2024 | 4 articles | Viewed by 10411 | Submission Open
Keywords: alpha-synuclein; molecular mechanisms; movement disorders; Parkinson’ s disease; dementia with lewy bodies; multiple-system atrophy; biomarkers; biochemistry; risk factors
(This special issue belongs to the Section Molecular Medicine)
Recent Developments in Mesenchymal Stem Cells submission deadline 30 Nov 2024 | 5 articles | Viewed by 8058 | Submission Open
Keywords: mesenchymal stromal cell; regenerative medicine; secretome
(This special issue belongs to the Section Cellular Biochemistry)
New Insights into Reactive Oxygen Species in Cell Death and Immunity
edited by , and Dhia Azzouz
submission deadline 30 Nov 2024 | 3 articles | Viewed by 7322 | Submission Open
Keywords: reactive oxygen species (ROS); cell death; immune response; ROS-mediated diseases; tools to study ROS
(This special issue belongs to the Section Cellular Biochemistry)
Molecular Mechanisms of Life-Extending Biomolecules and Interventions with Medical and Technological Implications
edited by
submission deadline 30 Nov 2024 | 1 articles | Viewed by 4763 | Submission Open
Keywords: biomolecules; genes; molecular and metabolic mechanisms; model systems; humans
(This special issue belongs to the Section Molecular Biology)
Role of Epigenetics in Organ Fibrosis
edited by
submission deadline 30 Nov 2024 | 1 articles | Viewed by 2724 | Submission Open
Keywords: chronic heart disease; cardiac fibrosis; heart failure; fibroblast; cardiomyocyte; DNA methylation; histone modification; non-coding RNA; gene therapy
(This special issue belongs to the Section Molecular Genetics)
Intracerebral Hemorrhage: Advances in Preclinical Studies: 2nd Edition submission deadline 30 Nov 2024 | 2 articles | Viewed by 2112 | Submission Open
Keywords: neuroinflammation; oxidative stress; neurodegeneration; neurological deficits; blood– brain barrier damage
(This special issue belongs to the Section Molecular Medicine)
The Immune System and Allergies
edited by
submission deadline 30 Nov 2024 | 1 articles | Viewed by 1801 | Submission Open
Keywords: immune system; allergy; inflammation; hypersensitivity; immunology
(This special issue belongs to the Section Cellular Biochemistry)
The Molecular and Pathophysiological Basis of Ectopic Fat Deposition in Non-Adipose Tissues submission deadline 30 Nov 2024 | 2 articles | Viewed by 1563 | Submission Open
Keywords: metabolic dysfunction-associated hepatosteatosis; myosteatosis; pancreatic steatosis; pancreatic adipocytes; visceral adipose tissue; cardiac steatosis; cardiac adipose tissue; kidney steatosis; macrophage steatosis; perirenal adipose tissue; lipophagy
(This special issue belongs to the Section Molecular Medicine)
Biomarkers in Metabolic Diseases, 2nd Edition submission deadline 30 Nov 2024 | 1 articles | Viewed by 1333 | Submission Open
Keywords: metabolic disorders; inborn errors of metabolism; surrogate biomarkers; biochemical markers; diagnostic markers; newborn screening; molecular analyses; metabolomics; disease progression; treatment efficacy
(This special issue belongs to the Section Molecular Biomarkers)
Recent Advances in Cellular and Molecular Mechanisms of Cardiovascular and Metabolic Diseases: 2nd Edition
edited by
submission deadline 30 Nov 2024 | 1 articles | Viewed by 979 | Submission Open
Keywords: cardiovascular disease; dyslipidemia; diabetes; obesity; inflammation; oxidative stress; biomarkers; microRNA; extracellular vesicles; cardiopulmonary disease
(This special issue belongs to the Section Molecular Biology)
Recent Advances in the Enzymatic Synthesis of Bioactive Compounds submission deadline 30 Nov 2024 | Viewed by 469 | Submission Open
Keywords: biocatalysis; biotransformation; enzyme-catalyzed reactions; whole-cell catalysis; green chemistry; enzymes; phenolic compounds; polyphenols; lipases; lipophilization; enzymatic synthesis; esterification; transesterification; green and sustainable chemistry approaches; lipid modification
(This special issue belongs to the Section Natural and Bio-derived Molecules)
Molecular Mechanisms of Male Infertility submission deadline 30 Nov 2024 | Viewed by 378 | Submission Open
Keywords: male infertility; microRNA; NGS; molecular mechanism
(This special issue belongs to the Section Molecular Reproduction)
Melanin-Related Biomolecules: Synthesis, Properties and Applications
edited by Kazumasa Wakamatsu and
submission deadline 30 Nov 2024 | Viewed by 369 | Submission Open
Keywords: melanin; skin aging; hair color; photoaging; antioxidant action; UV protection; cosmetology; display technology; food industry
Immune Modulation and Atherosclerosis
edited by Xinjie Lu
submission deadline 30 Nov 2024 | Viewed by 361 | Submission Open
Keywords: atherosclerosis; cardiovascular disease; immune modulatory therapy; vaccinations
(This special issue belongs to the Section Molecular Medicine)
Molecular Mechanisms of Cardiovascular Remodeling
edited by
submission deadline 30 Nov 2024 | Viewed by 349 | Submission Open
Keywords: vascular remodeling aging; extracellular matrix; atherosclerosis peripheral; artery disease; chronic heart failure; cardiovascular associated cognitive decline
(This special issue belongs to the Section Molecular Biology)
Epstein-Barr Virus Disease Mechanisms and Stress Responses: 2nd Edition submission deadline 30 Nov 2024 | Viewed by 285 | Submission Open
Keywords: Epstein– Barr virus (EBV); reactivation; immune modulation; stress; aging
(This special issue belongs to the Section Molecular Medicine)
Recent Advances in Research on Chromosome Abnormalities and Genomic Disorders
edited by and Vijay S. Tonk
submission deadline 30 Nov 2024 | Viewed by 284 | Submission Open
Keywords: genomic testing; whole-exome sequencing; microarray analysis; cytogenetics; DNA diagnosis; DNA variation; DNA variant qualification; genetic disease
(This special issue belongs to the Section Molecular Genetics)
Obesity, Adipose Tissue and Cardiovascular Diseases: 2nd Edition
edited by
submission deadline 30 Nov 2024 | Viewed by 217 | Submission Open
Keywords: obesity; cardiovascular diseases (CVDs); hypertension; dyslipidemia; atherosclerosis; adipose tissue; adipokines; cytokines
(This special issue belongs to the Section Molecular Biology)
Advances in Liver Transplantation and Hepatocellular Carcinoma
edited by
submission deadline 30 Nov 2024 | Viewed by 202 | Submission Open
Keywords: biomolecular markers of liver graft quality; the prediction role of biomolecular markers in liver transplantation; biomolecular markers of graft viability in the setting of machine perfusion technology; biomolecular markers of liver graft dysfunction; HCC biomarkers: AFP; PIVKA; and SPIK; the role of inflammation and immunity; standards of biomolecular HCC diagnosis; biomolecular-based diagnostic algorithms for HCC; biomolecular-based screening and prevention algorithms; advantages and pitfalls of existing biomolecular diagnosis
(This special issue belongs to the Section Molecular Biomarkers)
Recent Developments in Biohybrid Systems for Human Pluripotent Stem Cells and Beyond submission deadline 30 Nov 2024 | Viewed by 200 | Submission Open
Keywords: biohybrid systems; cell– material interaction; stem cells
(This special issue belongs to the Section Cellular Biochemistry)
Protein Interplay in Neurodegeneration, 2nd Edition
edited by
submission deadline 30 Nov 2024 | Viewed by 177 | Submission Open
Keywords: amyloidogenic proteins; metal ions; ROS; protein misfolding; neurons
(This special issue belongs to the Section Biomacromolecules: Proteins)
Covalent and Non-covalent Functions of Ubiquitin and Ubiquitin-Like Molecules: Emerging Concepts
edited by Elena Santonico and Dmitris Xirodimas
submission deadline 30 Nov 2024 | Viewed by 149 | Submission Open
Keywords: ubiquitin; ubiquitin-like (UBL); post-translational modification (PTM); protein degradation; E1; E2; E3
Biomolecules and Biomaterials for Tissue Engineering, 2nd Edition
edited by
submission deadline 10 Dec 2024 | Viewed by 231 | Submission Open
Keywords: tissue engineering; bioactive molecules; cellular function; proliferation
(This special issue belongs to the Section Biological and Bio- Materials)
Recent Advances in Histone Deacetylase Research in Health and Disease
edited by and
submission deadline 15 Dec 2024 | 3 articles | Viewed by 5828 | Submission Open
Keywords: histone deacetylase; HDAC inhibitor; deacetylation; enzymatic and non-enzymatic activity; epigenetics; human disease
(This special issue belongs to the Section Enzymology)
Regulation of Notch Signaling Pathway and Its Relation to Diseases
edited by
submission deadline 15 Dec 2024 | 2 articles | Viewed by 4772 | Submission Open
(This special issue belongs to the Section Molecular Medicine)
Mitochondrial Proteins: From Import and Biogenesis to Complex Functional Network submission deadline 15 Dec 2024 | 1 articles | Viewed by 4665 | Submission Open
Keywords: mitochondrial proteins; import; biogenesis; metabolism; functional network; oxidative stress; small molecules; mitochondrial protein quality control; mitophagy
(This special issue belongs to the Section Biomacromolecules: Proteins)
Tuberculosis: Immunopathogenesis and Therapeutic Strategies submission deadline 15 Dec 2024 | 2 articles | Viewed by 3786 | Submission Open
Keywords: tuberculosis; drug resistance; granulomatous inflammation; pathogenesis; immune responses; immunomodulation; host-directed therapy; antimicrobial treatment; antimicrobial mechanisms; antimicrobial agents
(This special issue belongs to the Section Molecular Medicine)
Drosophila as a Model System to Study Metabolism
edited by
submission deadline 15 Dec 2024 | 2 articles | Viewed by 2582 | Submission Open
Keywords: carbohydrate; lipid; amino acid; Drosophila; metabolism; insulin; TOR; autophagy; fasting
(This special issue belongs to the Section Molecular Biology)
Bioactive Molecules in the Control of Oxidative Stress and Oxidative Stress-Related Diseases
edited by
submission deadline 15 Dec 2024 | 1 articles | Viewed by 1704 | Submission Open
Keywords: antioxidants; bioactive molecules; ROS; redox signaling; oxidative stress-related diseases
(This special issue belongs to the Section Molecular Medicine)
Human Gut Microbiome and Diet in Health and Diseases: 2nd Edition
edited by
submission deadline 15 Dec 2024 | 1 articles | Viewed by 1311 | Submission Open
Keywords: gut microbiome; microbiota; nutrition; functional foods; mucosal immunity; dysbiosis
(This special issue belongs to the Section Molecular Medicine)
Omics Technologies in Precision Medicine: Bridging Disease Research to Clinical Applications
edited by Xiao Chang
submission deadline 15 Dec 2024 | Viewed by 400 | Submission Open
Keywords: genome sequencing; single-cell sequencing; transcriptomics; proteomics; polygenic diseases
(This special issue belongs to the Section Bioinformatics and Systems Biology)
Embryo Implantation: New Molecular Insights in Endometrial Receptivity, Trophoblast Invasion and Signaling
edited by , Evdokia Dimitriadis and Lois A. Salamonsen
submission deadline 15 Dec 2024 | Viewed by 343 | Submission Open
Keywords: embryo implantation; endometrial receptivity; trophoblast invasion; signaling
Recent Advances in RNA Editing and Modification submission deadline 15 Dec 2024 | Viewed by 260 | Submission Open
Keywords: RNA editing; RNA modification; deamination; transamination; pseudouridylation
Molecular Basis and Novel Treatment of Epilepsy
edited by
submission deadline 15 Dec 2024 | Viewed by 158 | Submission Open
Keywords: epilepsy; genetic basis; epileptogenesis; antiseizure drugs; novel treatment; translational research
(This special issue belongs to the Section Molecular Biology)
Tissue Calcification in Normal and Pathological Environments
edited by
submission deadline 20 Dec 2024 | 3 articles | Viewed by 6075 | Submission Open
Keywords: calcification; ectopic mineralization; bone; heterotopic ossification; calcium phosphate; calcium carbonate; calcium oxalate; procalcific cell death
(This special issue belongs to the Section Molecular Medicine)
New Insights into Essential Genes and Functions submission deadline 20 Dec 2024 | 3 articles | Viewed by 5516 | Submission Open
Keywords: gene regulation; omics data; essentiality; epigenetics; machine learning
(This special issue belongs to the Section Molecular Genetics)
State of the Art of Myology in 2024 submission deadline 20 Dec 2024 | 2 articles | Viewed by 3793 | Submission Open
Keywords: embryonic myogenesis; adult myogenesis; exercise-induced muscle injury; muscular dystrophies and muscle diseases; sarcopenia; cachexia; rhabdomyosarcoma; muscle biophysics
(This special issue belongs to the Section Molecular Biology)
Cytoskeleton Structure and Dynamics in Health and Disease
edited by Alla S. Kostyukova and
submission deadline 20 Dec 2024 | 1 articles | Viewed by 1361 | Submission Open
Keywords: actin; myosin; cytoskeleton; membrane-cytoskeleton associations; mechanotransduction; cytokinesis; nuclear cytoskeleton; contractile systems; cell motility; cell morphogenesis; cell adhesions; signal transduction; cytoskeleton structure and dynamics; microtubules; actin filaments; intermediate filaments organization
(This special issue belongs to the Section Biomacromolecules: Proteins)
Breast Cancer: Molecular Mechanisms and Targeted Therapies
edited by
submission deadline 20 Dec 2024 | Viewed by 343 | Submission Open
Keywords: breast cancer; breast cancer metastasis; cancer metabolism; molecular and cellular basis of breast cancer; chemoresistance in breast cancer; triple-negative breast cancer and breast cancer stem cell
(This special issue belongs to the Section Molecular Medicine)
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