Novel Drug Targets and RNA Epigenetics in Cancer Therapy

A special issue of Biomolecules (ISSN 2218-273X). This special issue belongs to the section "Molecular Structure and Dynamics".

Deadline for manuscript submissions: 30 June 2025 | Viewed by 15

Special Issue Editor


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Guest Editor
University of Texas Health Science Center at San Antonio, Department of Cell Systems and Anatomy, San Antonio, TX, USA
Interests: RNA epigenetics; drug development; tumor microenvironment

Special Issue Information

Dear Colleagues,

RNA epigenetics, encompassing modifications such as methylation, acetylation, and pseudouridylation of RNA molecules, has emerged as a crucial layer of gene expression regulation. These modifications influence RNA stability, localization, translation, and splicing, significantly impacting cellular processes. Aberrations in RNA epigenetics have been increasingly linked to cancer progression and drug resistance, making them promising targets for novel therapeutic strategies.

In this Special Issue, we aim to highlight the recent advancements in understanding RNA epigenetics and its role in cancer biology. We encourage submissions that explore novel drug targets related to RNA modifications, such as RNA methyltransferases, demethylases, and RNA-binding proteins, as well as the development of small-molecule inhibitors or RNA-targeted therapies. Additionally, we welcome contributions that utilize cutting-edge technologies, including RNA-seq, CRISPR screening, and single-cell analysis, to investigate the dynamics of RNA modifications in tumorigenesis and therapeutic response.

By focusing on these novel drug targets and the role of RNA epigenetics in cancer growth, progression, and therapy resistance, this Special Issue seeks to provide insights into innovative approaches for precision oncology. We invite researchers to contribute original research articles, reviews, and short communications to advance the field of RNA epigenetics in cancer treatment.

Prof. Dr. Manjeet K. Rao
Guest Editor

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Keywords

  • RNA modifications
  • cancer epigenetics
  • novel drug targets
  • RNA therapeutics
  • tumorigenesis

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Published Papers

This special issue is now open for submission.
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