Mental Health: From a Neurobiology Perspective

A special issue of Brain Sciences (ISSN 2076-3425). This special issue belongs to the section "Molecular and Cellular Neuroscience".

Deadline for manuscript submissions: 13 June 2025 | Viewed by 2333

Special Issue Editors


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Guest Editor
Graduate Program in Biomedical Sciences, Federal University of Fronteira Sul, Chapecó 89815-899, SC, Brazil
Interests: psychiatric disorders; translational neuroscience; biological mechanisms; neuroinflammation; epigenetics; neurotransmission; new therapeutic strategies
Special Issues, Collections and Topics in MDPI journals

E-Mail Website
Guest Editor
Graduate Program in Biomedical Sciences, Federal University of Fronteira Sul, Chapecó 89815-899, SC, Brazil
Interests: ectonucleotidases; oxidative stress; neurodegenerative diseases
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Background and history of this topic: Understanding mental health from a neurobiology perspective has gained significant traction in recent decades, propelled by advances in neuroscience and psychology. The advent of technologies like neuroimaging and molecular biology has opened new avenues for exploring the underlying neurobiological mechanisms of mental health disorders.

Aim and scope of the Special Issue: This Special Issue aims to provide a comprehensive overview of the latest research and insights into mental health from a neurobiology perspective. It delves into the neurobiological underpinnings of various mental health conditions, exploring novel therapeutic interventions targeting neurobiological pathways to advance the understanding and treatment of mental health disorders.

Cutting-edge research: Cutting-edge research in mental health neurobiology spans various fronts, such as identifying neural circuits for mood and anxiety, understanding neuroinflammation in psychiatric disorders, studying genetic and epigenetic influences on mental illness, exploring early life stress effects on brain development, advancing neuroimaging for mental disorder diagnosis, identifying biomarkers for early detection and treatment, and using computational methods for data analysis.

What kind of papers we are soliciting: In this Special Issue, we invite researchers to submit original research manuscripts, reviews, and mini reviews related to understanding mental health and psychiatric disorders, focusing on the various biological and neurobiological mechanisms involved.

Dr. Zuleide Maria Ignácio
Dr. Margarete Dulce Bagatini
Guest Editors

Manuscript Submission Information

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Keywords

  • neurobiology
  • mental health
  • psychiatric disorders
  • neurotransmission
  • signaling pathway
  • genetic and epigenetic factors
  • neurodevelopment
  • inflammation
  • therapeutic interventions
  • translational and clinical research

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Published Papers (1 paper)

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23 pages, 803 KiB  
Systematic Review
Neuroanatomical and Neurocognitive Differences Between the Executive Functions in Child Sexual Offenders: A Systematic Review
by Yaiza Ara-García, Manuel Martí-Vilar, Laura Badenes-Ribera and Francisco González-Sala
Brain Sci. 2025, 15(1), 38; https://doi.org/10.3390/brainsci15010038 - 2 Jan 2025
Viewed by 1191
Abstract
Background/Objectives: Studies on executive functions in child sex offenders relate their findings to the presence of pedophilia, but they are not able to distinguish between paraphilia and abuse. It is therefore this lack of a distinction that leads us to complement the existing [...] Read more.
Background/Objectives: Studies on executive functions in child sex offenders relate their findings to the presence of pedophilia, but they are not able to distinguish between paraphilia and abuse. It is therefore this lack of a distinction that leads us to complement the existing information. Thus, the purpose of this review is to find all available evidence on the neurocognitive and neuroanatomical differences in executive functions among pedophilic and non-pedophilic child sex offenders, and non-offender pedophiles. Methods: The present review, in accordance with the PRISMA statement, ran a systematic search of three databases (Web of Science, Scopus and ProQuest). This search identified 5697 potential articles, but only 16 studies met all the inclusion criteria. Most of the studies were conducted in Europe, using a cross-sectional design with a convenience sample. Results: The results showed alterations in frontal, temporal and parietal structures related to executive functions (e.g., response inhibition) in child sexual offenders, regardless of the presence of pedophilia. Conclusions: In summary, there are differences in brain structure underlying executive functions related to child sexual abuse, but not to pedophilia as such. Full article
(This article belongs to the Special Issue Mental Health: From a Neurobiology Perspective)
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