Narcolepsy and Its Implication in Quality of Life
A special issue of Brain Sciences (ISSN 2076-3425). This special issue belongs to the section "Clinical Neuroscience".
Deadline for manuscript submissions: closed (31 July 2023) | Viewed by 8700
Special Issue Editor
2. Faculty of Medicine, University of Melbourne, Parkville, VIC, Australia
Interests: brain disorders; pharmaceuticals; behavioral and social science; contraception/reproduction
Special Issue Information
Dear Collegues,
Narcolepsy is a chronic sleep disorder characterized by excessive daytime sleepiness, cataplexy, hypnagogic hallucinations, and sleep paralysis. This disease significantly affects overall patient functioning, interfering with social, work, and affective life. Some symptoms of narcolepsy depend on emotional stimuli; for instance, cataplectic attacks can be triggered by emotional inputs such as laughing, joking, a pleasant surprise, or anger. Nighttime (nocturnal) sleep patterns may also be disrupted. Three additional symptoms often associated with narcolepsy are sudden extreme muscle weakness (cataplexy), a specific type of hallucination that occurs just before falling asleep or upon awakening, and brief episodes of paralysis while waking up. Narcolepsy also may be associated with “automatic behavior”, that is, doing something automatically without any memory afterward. The incidence of narcolepsy is approximately 1 in 2000, and most researchers believe that the disorder remains undiagnosed or misdiagnosed in many affected individuals.
Narcolepsy and psychiatric disorders have a significant but unrecognized relationship, which is an area of evolving interest, but unfortunately, the association is poorly understood. It is not uncommon for the two to occur co-morbidly. However, narcolepsy is frequently misdiagnosed initially as a psychiatric condition, contributing to the protracted time to accurate diagnosis and treatment. Narcolepsy is a disabling neurodegenerative condition that carries a high risk for the development of social and occupational dysfunction. Deterioration in function may lead to the secondary development of psychiatric symptoms. Inversely, the development of psychiatric symptoms can lead to deterioration in function and quality of life.
This Special Issue aims to provide a collection of original research/review articles reflecting the most exciting and recent progress made in all aspects of the field.
Dr. Philippe Lehert
Guest Editor
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Keywords
- narcolepsy
- schizophrenia
- attention deficit hyperactivity disorder
- depression
- anxiety
- psychiatric disorders
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