Tourette Syndrome and Comorbid Conditions
A special issue of Brain Sciences (ISSN 2076-3425). This special issue belongs to the section "Neuromuscular and Movement Disorders".
Deadline for manuscript submissions: closed (15 October 2021) | Viewed by 3443
Special Issue Editors
Interests: Tourette Syndrome; ADHD; Autism spectrum disorder; Obsessive compulsive disorder; neurodevelopmental disorders
Special Issue Information
Dear Colleagues,
Tourette syndrome (TS) is a neurodevelopmental disorder characterized by multiple involuntary motor and vocal tics. According to the Diagnostic and Statistical Manual of Mental Disorders, its diagnosis requires the presence of two or more motor tics and at least one vocal tic, occurring at least once a day and for over one year since onset. The estimated TS prevalence is approximately 1%, with a male/female ratio of 4:1. The onset occurs typically in childhood, and in most cases, patients improve by late adolescence. In addition, 85% of children affected by TS present other comorbidities (e.g., ADHD, obsessive-compulsive disorder (OCD), anxiety, ASD, learning and sleep disorders), which could be more impairing than tics themselves.
The most frequent comorbidities, such as ADHD and OCD, were investigated in the last few years, and a large amount of information was obtained with regard to their clinical, neuropsichological, etiological, and genetic aspects, which has allowed the improvement of their treatment (pharmacological or behavioral). Less is known with regard to other comorbidities, such as ASD, sleep disorders, learning and intellectual disabilities, enuresis, etc. With this Special Issue, we would like to focus on these comorbidies that, though less frequently, could also impare the life of a TS patient and sometimes need to be treated together with tics.
In this Special Issue, we would like to present and discuss neuropsichological findings, social impact, treatments, as well as neuroimaging and genetic issues related to these less frequent comorbidities in order to improve our knoledge on Tourette syndrome and its comorbidities.
We solicit case reports, original articles, and clinical reviews.
Dr. Mariangela Gulisano
Prof. Renata Rizzo
Guest Editors
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Keywords
- Gilles de la Tourette Syndrome
- Autism spectrum disorder
- Sleep disorders
- Learning disbilities
- Enuresis
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