RNA-Based Drug Discovery and Development for Neurological Conditions
A special issue of Brain Sciences (ISSN 2076-3425). This special issue belongs to the section "Neuropharmacology and Neuropathology".
Deadline for manuscript submissions: closed (10 August 2024) | Viewed by 195
Special Issue Editor
Interests: pain mechanisms; cancer pain; neuropathic pain; painful diabetic peripheral neu-ropathy; gene regulation; non-coding RNAs; microRNAs; long non-coding RNAs; genome regulations; RNA therapeutics; itch mechanisms; RNA-therapeutics
Special Issue Information
Dear Colleagues,
Recent breakthroughs have illuminated RNA's pivotal role as a versatile tool in combating a spectrum of challenging neurological disorders. Exciting discoveries in RNA-based biomarkers and novel mechanisms of action have illuminated new paths for therapeutic intervention, heralding a new era of precision medicine. To propel the rapid expansion of the field, there is an urgent need to enhance the efficacy of RNA-based therapeutics and devise innovative modes of delivery. Novel strategies that enable the precise targeting of specific cell types within the complex neural environment are paramount, aiming to maximize therapeutic efficacy while minimizing off-target effects. A comprehensive understanding of the complex interplay within diverse RNA classes in organisms' development and disease is still in its infancy.
Share your insights, innovations, and findings with Brain Sciences, where they will catalyze new discoveries and drive progress in the quest for effective neurological therapies. By submitting your manuscripts, you will not only amplify the impact of your work but also inspire collaboration and cross-disciplinary exchange. Together, let us harness the power of RNA to revolutionize neurological care, offering hope to millions worldwide.
We invite original research articles and reviews that explore the frontiers of RNA-based drug discovery and development, delving into the intricacies of RNA-based biomarkers, novel mechanisms, mode of delivery, and strategies to enhance therapeutic efficacy. Discovery of the vast potential of RNA therapeutics, including antisense oligonucleotides (ASOs), small interfering RNA (siRNA), messenger RNA (mRNA) therapeutics, RNA editing technologies, and non-coding RNAs, in the clinical setting as well as with animal models is anticipated.
Dr. Kiran K. Bali
Guest Editor
Manuscript Submission Information
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Keywords
- Alzheimer's disease
- Parkinson's disease
- Huntington's disease
- amyotrophic lateral sclerosis (ALS)
- pain
- brain tumors
- brain cavernomas
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