Advances in Esophageal Cancer

A special issue of Cancers (ISSN 2072-6694). This special issue belongs to the section "Cancer Therapy".

Deadline for manuscript submissions: 15 August 2025 | Viewed by 111

Special Issue Editor


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Guest Editor
Department of Upper GI Surgery, Royal Marsden Hospital, London, UK
Interests: oesophageal cancer; gastric cancer; gastrointestinal stromal tumours; benign upper gastrointestinal surgery; upper gastrointestinal endoscopy
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Esophageal cancer is a disease with significant unmet clinical needs. Challenges in early diagnosis and ineffective systemic and local therapies contribute to why five-year survival is just 15%. Despite treatment with a potentially curative intent, nearly 40% of patients who achieve a complete pathological response recur within two years of completing treatment. Recurrent disease can present insidiously, and subsequent survival despite systemic and local therapy is often poor.

Detecting recurrent esophageal cancer remains a challenge. Although significant research has been undertaken on the role of serum biomarkers including circulating tumor DNA in disease surveillance and in monitoring response to therapy, there is a lack of assays with sensitivity and specificity adequate for use in the current mainstream practice. Early detection of recurrence may enable patients to undergo targeted therapy, thereby improving long-term survival.

This Special Issue focuses on the latest developments in monitoring efficacy of treatment, disease surveillance, and early detection of recurrence to help improve long-term survival.

Dr. Sacheen Kumar
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cancers is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • esophageal adenocarcinoma
  • esophageal squamous cell carcinoma
  • long-term survival
  • biomarkers
  • disease surveillance
  • treatment response

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Published Papers

This special issue is now open for submission.
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