Search for Articles:
Title / Keyword
Author / Affiliation / Email
Journal
Article Type
 
 
Advanced Search
 
Section
Special Issue
Volume
Issue
Number
Page
 
8.0
4.5
Journals
Cancers
Special Issues
New Developments in Adolescent and Young Adult Oncology
share announcement

New Developments in Adolescent and Young Adult Oncology

A special issue of Cancers (ISSN 2072-6694). This special issue belongs to the section "Clinical Research of Cancer".

Deadline for manuscript submissions: 24 October 2025 | Viewed by 744

Special Issue Editors

Dr. Olga Husson

E-Mail Website
Guest Editor
Department of Medical Oncology, Netherlands Cancer Institute, 1066 CX Amsterdam, The Netherlands
Interests: adolescent and young adult oncology; epidemiology; health-related quality of life; late effects; survivorship; rare cancers
Special Issues, Collections and Topics in MDPI journals
Prof. Dr. Winette T.A. van der Graaf

E-Mail Website
Guest Editor
Department of Medical Oncology, Netherlands Cancer Institute, 1066 CX Amsterdam, The Netherlands
Interests: adolescent and young adult oncology; epidemiology; health-related quality of life; late effects; survivorship; rare cancers
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Adolescent and young adult (AYA) oncology focuses on the unique medical and psychosocial needs of patients aged 15–39 who are diagnosed with cancer. This population faces distinct challenges, including delayed diagnoses, limited access to age-appropriate care, and interruptions in education or career development. AYA patients often experience higher rates of long-term treatment-related side effects and infertility concerns compared with other age groups. They also encounter barriers to clinical trial enrollment, impacting advancements in targeted therapies for this demographic. Emotional and social challenges, such as isolation and altered peer relationships, are prevalent and require integrated psychosocial support. Survivorship care is critical for AYAs due to their increased risk of late effects, secondary malignancies, and mental health issues. Fertility preservation options must be discussed prior to treatment, ensuring informed decision-making and future family planning opportunities. Multidisciplinary care teams, including oncologists, mental health professionals, and fertility specialists, are essential to address the complex needs of AYA patients. Advocacy efforts and specialized programs aim to improve AYA cancer outcomes by promoting research, awareness, and policy changes. Future research must continue to explore innovative therapies, survivorship strategies, and personalized care approaches for this vulnerable and often underserved group. This Special Issue will focus on all new developments in AYA oncology.

Yours faithfully,

Dr. Olga Husson
Prof. Dr. Winette T.A. van der Graaf
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cancers is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • adolescent and young adult oncology
  • epidemiology
  • health-related quality of life
  • late effects
  • survivorship
  • clinical care

Benefits of Publishing in a Special Issue

  • Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
  • Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
  • Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
  • External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
  • e-Book format: Special Issues with more than 10 articles can be published as dedicated e-books, ensuring wide and rapid dissemination.

Further information on MDPI's Special Issue polices can be found here.

Published Papers (1 paper)

Order results
Result details
Show export options expand_more Show export options expand_less
Select all
Export citation of selected articles as:

Review

19 pages, 4001 KiB  
Review
Core Patient-Centered Outcomes for Adolescents and Young Adults with Cancer: A Comprehensive Review of the Literature from the STRONG-AYA Project
by Silvie H. M. Janssen, Winette T. A. van der Graaf, Anna Hurley-Wallace, Carla Vlooswijk, Catarina S. Padilla, Charlotte Cairns, Connor J. Tyler, Emily I. Holthuis, Gudrun E. Rohde, Katherine J. Hunt, Kirsty Way, Konstantinos Angoumis, Lina H. Lankhorst, Maarten F. M. Engel, Maria-Sophie Rothmund, Milou J. P. Reuvers, Nicole Collaço, Richard Wagland, Samantha C. Sodergren, Simone Hanebaum, Thom Legendal, Thomas J. Cartledge, Tom I. Bootsma, Yushi Bai, Anne-Sophie Darlington and Olga Hussonadd Show full author list remove Hide full author list
Cancers 2025, 17(3), 454; https://doi.org/10.3390/cancers17030454 - 28 Jan 2025
Viewed by 607
Abstract
Background: In adolescents and young adults (AYAs) with cancer, the importance of patient-centered research outcomes is increasingly acknowledged and there is a need for consensus on the most relevant outcomes. This review provides a comprehensive overview of outcomes relevant to AYAs with cancer [...] Read more.
Background: In adolescents and young adults (AYAs) with cancer, the importance of patient-centered research outcomes is increasingly acknowledged and there is a need for consensus on the most relevant outcomes. This review provides a comprehensive overview of outcomes relevant to AYAs with cancer in order to develop an AYA-specific core outcome set (COS) as part of the European project STRONG-AYA. Methods: A literature search was conducted to identify relevant articles in five databases. Each article was reviewed by two independent researchers, using Rayyan (an online tool) to screen articles by their title/abstract and then by their full text. Subsequently, the data were extracted using a predefined, tailored extraction framework. Results: In total, 17,301 articles were screened, of which 1631 were included in the analyses. Registry studies (52.9%) were the most used study type. Well-represented continents were North America (50.3%) and Europe (27.8%). Of the five core areas, functioning (47.0%) and epidemiology (44.9%) were covered most often, followed by physiological/clinical (42.4%), resource use (6.1%), and adverse events (4.5%). The outcome domains that were represented the most include mortality/survival (43.1%), delivery of care (23.4%), outcomes relating to neoplasms (22.7%), and emotional functioning/well-being (19.2%). Conclusions: This literature review provides a foundation for the development of an AYA-specific COS for improving the relevance and efficiency of measuring outcomes, the pooling of (international) research data, and the value of care for current and future AYAs with cancer. Finalization and refinement of the COS should be a priority for future research. Full article
(This article belongs to the Special Issue New Developments in Adolescent and Young Adult Oncology)
►▼ Show Figures

Figure 1

Show export options expand_more Show export options expand_less
Select all
Export citation of selected articles as:
 
Displaying articles 1-1
Back to TopTop