Feature Papers in Section "Tumor Microenvironment"

Dear Colleagues,

We are excited to introduce a Special Issue of Cancers focused on Feature Papers in the Section "Tumor Microenvironment." This Special Issue aims to highlight the latest advancements and discoveries in understanding the complex interactions within the tumor microenvironment and their implications for cancer progression and treatment.

The tumor microenvironment plays a crucial role in tumor development, growth, and metastasis. It consists of various components, including immune cells, stromal cells, extracellular matrix, and signaling molecules. Recent advances in computational analysis and modeling utilizing single-cell transcriptomic data, bulk tumor expression profiles, and spatial transcriptomics have uncovered a wide array of intercellular signaling networks within the tumor microenvironment. The intricate interaction among tumor cell-intrinsic factors, cell-extrinsic influences, and systemic mediators of disease progression is essential for developing effective therapeutic strategies and improving patient outcomes.

We invite researchers and clinicians to submit their original research articles and reviews that delve into the diverse aspects of the tumor microenvironment. Some of the key topics of interest for this Special Issue include, but are not limited to, the following:

Cellular and molecular interactions within the tumor microenvironment;

Immune cell infiltration and immune response modulation;

Stromal cell contributions to tumor growth and metastasis;

Angiogenesis and vascularization in the tumor microenvironment;

Extracellular matrix remodeling and its impact on cancer progression;

Signaling pathways and molecular mechanisms involved in tumor–stroma crosstalk;

Therapeutic targeting of the tumor microenvironment for improved treatment outcomes.

All submitted articles will undergo a rigorous peer review process to ensure that the highest scientific quality and relevance to the field are ensured. We encourage contributions from experts in the field of tumor microenvironment research, as well as clinicians with valuable insights from patient care.

By bringing together cutting-edge research and clinical experiences, this Special Issue aims to advance our understanding of the tumor microenvironment and pave the way for novel therapeutic approaches to be used. We believe that your contributions will greatly contribute to the success of this Special Issue and have a significant impact on the field of cancer research.

If you have any questions or require further information, please do not hesitate to contact us. We are here to provide support and facilitate your participation in this Special Issue.

Thank you for your attention, and we eagerly anticipate receiving your valuable submissions.

Dr. Sanjay Gupta
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cancers is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

• tumor microenvironment
• cancer progression
• interactions
• therapeutic targeting
• immune response