Biocatalysis in Non-conventional Media 2024

A special issue of Catalysts (ISSN 2073-4344). This special issue belongs to the section "Biocatalysis".

Deadline for manuscript submissions: 31 May 2025 | Viewed by 778

Special Issue Editors


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Department of Chemistry, Norwegian University of Science and Technology, Høgskoleringen 5, 7491 Trondheim, Norway
Interests: biocatalysis; enantiopure biologically active compounds; chiral chromatography; natural product chemistry
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The Henry Wellcome Building for Biocatalysis, Biosciences, Biocatalysis Centre, University of Exeter, Stocker Road, Exeter EX4 4QD, UK
Interests: industrial biotechnology; biocatalysis; enzyme mechanisms
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MITR, Institute of Applied Radiation Chemistry, Faculty of Chemistry, Lodz University of Technology, Zeromskiego Street 116, 90-924 Lodz, Poland
Interests: bioeconomy; biocatalysis; glycobiology; metabolomics; industrial biotechnology
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Special Issue Information

Dear Colleagues,

This conference series was initiated in 1986 and organised by professors at University of Wageningen, The Netherlands, both in 1986 and in 1992. In 2005, the third conference in this series was organised at the University of Manchester, UK.  In 2008, the Lomonosow State University in Moscow, Russia, chaired the conference. In 2017, the fifth edition of this series was organised by professors at University of Rostock, Germany. The hybrid edition of the sixth BNCM conference was held in Milano in May 2022. The seventh International Conference on Biocatalysis in Non-conventional media (BNCM 2024, https://www.ntnu.edu/bncm2024) will be organised in Trondheim, Norway, 26–29 May, and the newest research from experts in the field of biocatalysed reactions, both in academia and industry, will be presented. Moreover, the participants of BNCM 2024 will have the opportunity to present their latest results via oral presentations. Young researchers and PhD students are encouraged to present their work as posters.

The present Special Issue will feature the works presented at BNCM 2024, as well as additional contributions in the field of biocatalysis, ranging from synthesis and characterizations to catalytic applications. In detail, this Special Issue will cover the following topics: (i) novel non-conventional reaction media for biocatalysis; (ii) water- and solvent-free reaction systems; (iii) non-conventional media in flow biocatalysis; (iv) biphasic and multi-phase biocatalytic systems; (v) BNCM, from labscale to industrial scale; (vi) kinetics and thermodynamics of enzyme-catalyzed reactions in non-conventional media; (vii) non-conventional media for whole-cell versus cell-free biocatalytic systems; and (viii) sustainable biocatalytic reaction engineering in non-conventional media.

Authors with expertise in any of the above topics are cordially invited to submit their manuscripts to this Special Issue of Catalysts. Significant full papers and review articles are very welcome.

Dr. Elisabeth Egholm Jacobsen
Prof. Dr. Jennifer Littlechild
Prof. Dr. Roland Wohlgemuth
Guest Editors

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Keywords

  • enzyme catalysis
  • non-conventional media
  • industrial biotechnology
  • flow biocatalysis
  • sustainable chemistry

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Published Papers (1 paper)

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Research

11 pages, 483 KiB  
Article
Reformulated Kinetics of Immobilized Enzymes in Non-Conventional Media: A Case of Lipase-Catalyzed Esterification
by Emmanuel M. Papamichael and Panagiota-Yiolanda Stergiou
Catalysts 2024, 14(11), 830; https://doi.org/10.3390/catal14110830 - 18 Nov 2024
Viewed by 326
Abstract
Several approaches have been reported that aim to achieve simplified standardizations of the kinetic behavior of immobilized enzymes under specific experimental conditions. We have previously published simplified rate equations based on the kinetics of immobilized enzymes. Recently, new experimental results have become available [...] Read more.
Several approaches have been reported that aim to achieve simplified standardizations of the kinetic behavior of immobilized enzymes under specific experimental conditions. We have previously published simplified rate equations based on the kinetics of immobilized enzymes. Recently, new experimental results have become available on the kinetics and mechanisms of esterifications catalyzed by immobilized lipase in unconventional media, and consequently, a reformulation of their kinetics is necessary. In this work, we report the development of simplified rate equations relating the aforementioned reaction conditions on a new basis, considering our kinetic and mechanistic results. We provide experimental evidence that two different mechanisms describe the esterifications catalyzed by immobilized lipase, either in anhydrous organic solvent (n-hexane) or under non-solvent conditions. A ping-pong bi–bi mechanism with double dead-end substrate inhibition by both the fatty acid and the alcohol has been found to apply in the former case, while in the latter case the esterification proceeds via an ordered bi–bi mechanism with single dead-end substrate inhibition by ethanol. This study may be biotechnologically useful, as the increased use of immobilized enzymes, whether in academic research or in industry, requires sustainable development of new and environmentally friendly synthetic processes. Full article
(This article belongs to the Special Issue Biocatalysis in Non-conventional Media 2024)
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