Natural Killer Cells in Cancer Immunotherapy: Molecular Mechanisms, Diagnostic and Therapeutic Opportunities
A special issue of Cells (ISSN 2073-4409). This special issue belongs to the section "Cellular Immunology".
Deadline for manuscript submissions: 20 February 2025 | Viewed by 102
Special Issue Editor
Interests: innate immunity; NK cells; cytokines; immunomodulation; oncology; hematology; biochemistry; tumor markers; molecular markers; polymorphisms
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Since the discovery and first description of natural killer (NK) cells, a special population of peripheral blood lymphocytes, these cells have received great scientific interest. NK cells were first described as large granular lymphocytes with a specific morphology and role in oncology. Today, with the help of new technologies of molecular medicine and multicolor flow cytometry, the focus of global research is the examination of markers responsible for the activation and inhibition of NK cells, as well as gene regulation, in light of understanding tumor suppression in oncology patients. NK cell function is also based on a specifically adjusted balance between signals arising from inhibitory and activating receptors in contrast to T cytotoxic lymphocytes.
Based on the latest knowledge and information about NK cells, this Special Issue aims to further discuss and analyze the new molecular mechanisms involved in the regulation of NK cells and their importance in disease diagnosis and during progression, with special reference to the balance between the immune system and cancer. At the same time, via the development of new technologies for the separation and purification of the NK cell population, ex vivo manipulation has enabled the use of NK cells in immunotherapy and transplantation. We hope that such research and original results will provide new and realistic knowledge about the possibilities of treating malignant diseases, as well as an understanding of all the complex processes and principles of immunology. Together, this can be of great importance in clinical practice. That is why we invite authors from this field to contribute new knowledge about NK cells.
Prof. Dr. Vladimir Jurisic
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cells is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- natural killer cells
- immunotherapy
- solid tumors
- tumor suppression
- immunomodulation
- clinical practice
Benefits of Publishing in a Special Issue
- Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
- Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
- Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
- External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
- e-Book format: Special Issues with more than 10 articles can be published as dedicated e-books, ensuring wide and rapid dissemination.
Further information on MDPI's Special Issue polices can be found here.
