Exclusive Review Papers in "Cell Proliferation and Division" Section
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Editor
Dr. Lon J. van Winkle
Dr. Lon J. van Winkle
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Collection Editor
1. Department of Biochemistry, Midwestern University, Downers Grove, IL 60515, USA
2. Department of Medical Humanities, Rocky Vista University, Parker, CO 80122, USA
Interests: cell physiology; cell metabolism; development; cell differentiation; stem cells
Special Issues, Collections and Topics in MDPI journals
Topical Collection Information
Dear Colleagues,
Under the Section “Cell Division and Proliferation”, we aim to set up a Topical Collection to publish high-quality review papers related to cell division, proliferation, and the epigenetics of these processes. The topics of interest include, but are not limited to, the following:
- Cell division;
- Cell proliferation;
- Cell cycle;
- Mitosis;
- Meiosis;
- Reproduction;
- Cyclins;
- Cytokinesis;
- Centromeres;
- Kinetochore;
- Cohesin;
- Kinesins;
- Epigenetics of these entities and processes.
This Topical Collection is intended to contribute to the compilation of the current knowledge on cell division and proliferation as well as make it available to a broad readership. Distinguished researchers from all over the world, working in all related fields, are therefore invited to contribute to this review series. All papers will be published on an ongoing basis with full open access. We are looking forward to receiving your interesting contributions.
Dr. Lon J. van Winkle
Collection Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the collection website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cells is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript.
The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs).
Submitted papers should be well formatted and use good English. Authors may use MDPI's
English editing service prior to publication or during author revisions.
Published Papers (1 paper)
2023
Open AccessReview
Essential Protein PHB2 and Its Regulatory Mechanisms in Cancer
by
Amanda Qi, Lillie Lamont, Evelyn Liu, Sarina D. Murray, Xiangbing Meng and Shujie Yang
Cited by 14 | Viewed by 3487
Abstract
Prohibitins (PHBs) are a highly conserved class of proteins and have an essential role in transcription, epigenetic regulation, nuclear signaling, mitochondrial structural integrity, cell division, and cellular membrane metabolism. Prohibitins form a heterodimeric complex, consisting of two proteins, prohibitin 1 (PHB1) and prohibitin
[...] Read more.
Prohibitins (PHBs) are a highly conserved class of proteins and have an essential role in transcription, epigenetic regulation, nuclear signaling, mitochondrial structural integrity, cell division, and cellular membrane metabolism. Prohibitins form a heterodimeric complex, consisting of two proteins, prohibitin 1 (PHB1) and prohibitin 2 (PHB2). They have been discovered to have crucial roles in regulating cancer and other metabolic diseases, functioning both together and independently. As there have been many previously published reviews on PHB1, this review focuses on the lesser studied prohibitin, PHB2. The role of PHB2 in cancer is controversial. In most human cancers, overexpressed PHB2 enhances tumor progression, while in some cancers, it suppresses tumor progression. In this review, we focus on (1) the history, family, and structure of prohibitins, (2) the essential location-dependent functions of PHB2, (3) dysfunction in cancer, and (4) the promising modulators to target PHB2. At the end, we discuss future directions and the clinical significance of this common essential gene in cancer.
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