Electrochemical Sensors in Bioanalytical Chemistry

A special issue of Chemosensors (ISSN 2227-9040). This special issue belongs to the section "Electrochemical Devices and Sensors".

Deadline for manuscript submissions: 31 May 2025 | Viewed by 3317

Special Issue Editors


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Department of Chemical Science and Technologies, University of Rome Tor Vergata, 00133 Rome, Italy
Interests: analytical electrochemistry; electrochemical sensors; enzymatic biosensors; label-free immunosensors; screen-printed electrodes; nanomaterial-based sensors and biosensors; biochar as a green electrode modifier and enhancer; biosensing for clinical and food-safety control

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Institute of Crystallography, National Research Council of Italy, Via Salaria Km. 29,300, 00015 Monterotondo, Rome, Italy
Interests: photosynthesis-based biosensors; nanosensors; engineered bioreceptors; immobilization techniques; prototype design; agri-food; space biology
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Special Issue Information

Dear Colleagues,

Electrochemical sensors have emerged as sensitive and selective devices for targeted and multiplexed analyses in complex systems and found applications in multidisciplinary fields including, among others, medicine, agri-food, and environmental science. The analytical robustness, reliability, cost-effectiveness, integrability, and versatility of heterogeneous and homogeneous configurations account for the widespread fabrication and successful exploitation of electrochemical sensors achieved during the last few decades. Furthermore, the intrinsic features of electrochemical methods made downscaling of the measuring systems possible, giving rise to the development of lab-on-chips, point-of-care testing, and wearable devices emerging as breakthrough technologies in translational research.

Electrochemical transducers are at the core of electrochemical sensors and convert chemical information into measurable electrical signals (such as current, voltage, charge, and impedance) in a proportional manner to the analyte’s concentration. The intervention of nanomaterials, nanocomposites and conducting polymers in electrochemical sensor build-up, along with improvements in miniaturization techniques, and engineering of chemical and biological matter contributed to the development of sensors with unprecedentedly high sensitivity and selectivity parameters.

This Special Issue covers the latest advances in electrochemical sensors development, focusing on all aspects of design, fabrication, and implementation strategies exploiting functional materials and natural or biomimetic materials.

Dr. Rocco Cancelliere
Dr. Laura Micheli
Dr. Giuseppina Rea
Guest Editors

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Published Papers (1 paper)

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Research

13 pages, 5228 KiB  
Article
Detection of Levofloxacin Using a Simple and Green Electrochemically Polymerized Glycine Layered Carbon Paste Electrode
by Kanthappa Bhimaraya, Jamballi G. Manjunatha, Karnayana P. Moulya, Ammar M. Tighezza, Munirah D. Albaqami and Mika Sillanpää
Chemosensors 2023, 11(3), 191; https://doi.org/10.3390/chemosensors11030191 - 13 Mar 2023
Cited by 23 | Viewed by 2369
Abstract
The easy and rapid analytical tool, electrochemically polymerized (EP) glycine (GN) layered carbon paste electrode (LCPE), was used for the analysis of levofloxacin (LN) using cyclic voltammogram (CV) and differential pulse voltammetry (DPV). The surface features and activities of the electrochemical sensors EPGNLCPE [...] Read more.
The easy and rapid analytical tool, electrochemically polymerized (EP) glycine (GN) layered carbon paste electrode (LCPE), was used for the analysis of levofloxacin (LN) using cyclic voltammogram (CV) and differential pulse voltammetry (DPV). The surface features and activities of the electrochemical sensors EPGNLCPE and bare carbon paste electrode (BCPE) were analyzed using electrochemical impedance spectroscopy (EIS), field emission scanning electron microscopy (FE-SEM), CV and DPV methods. The modified sensor (EPGNLCPE)offers a vibrant and sensitive electrochemical LN oxidation peak by controlling overpotential and the electrode material fouling effect unlike BCPE. Under improved experimental conditions, the DPV method was used to analyze LN on EPGNLCPE by varying its concentration in 0.2 M phosphate buffer solution from 30 to 90 µM, resulting in a good linear relationship(between peak current and concentration), lower limit of detection (LOD: 8.436 × 10−7 M) and lower limit of quantification (LOQ: 2.812 × 10−6 M). Finally, real-time application of the sensor was tested by analyzing LN in medicinal samples, and good LN recovery was observed. Full article
(This article belongs to the Special Issue Electrochemical Sensors in Bioanalytical Chemistry)
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