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Chemosensors
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Advanced Surface Plasmon Resonance Sensors
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Advanced Surface Plasmon Resonance Sensors

A special issue of Chemosensors (ISSN 2227-9040). This special issue belongs to the section "Optical Chemical Sensors".

Deadline for manuscript submissions: 31 December 2024 | Viewed by 7268

Special Issue Editors

Dr. Erick Reyes Vera

E-Mail Website
Guest Editor
Department of Electronic and Telecommunications, Instituto Tecnologico Metropolitano, Medellín 050034, Colombia
Interests: photonic; photonic crystal fibers; optical fiber sensors; plasmons; machine learning; deep learning; data science
Dr. Kaiwei Li

E-Mail Website
Guest Editor
Key Laboratory of Bionic Engineering of Ministry of Education, Jilin University, Changchun 130022, China
Interests: optical fiber sensors; specialty optical fibers; tactile sensors
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Because of their great sensitivity, surface plasmon resonance (SPR) sensors have been actively investigated as a sensing mechanism for chemical and biological molecules in recent years. On the other hand, the utilization of nanostructures and advances in thin film production processes have permitted the development of more sensitive sensing devices that can be multiplexed. The unique optical and electrical characteristics of nanomaterials and dielectric films have enabled the progress of applications such as localized surface plasmon resonance (LSPR) and surface-enhanced Raman scattering (SERS). Furthermore, lithographic patterning of nanopatterned structures has resulted in high spatial resolution surface structures, while improving system sensitivity. In this Special Issue, we would like to compile the most recent theoretical and experimental research results related to this measurement principle, sensing formats, fabrication techniques, integration with artificial intelligence, optimization, and applications of surface plasmon sensors in industrial situations.

Therefore, we invite you to submit original research or review articles for this Special Issue, with emphasis on the most recent advances in SPR, or LSPR-based chemosensors, and their applications to the examination of chemical and biological samples.

Dr. Erick Reyes-Vera
Dr. Kaiwei Li
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Chemosensors is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • surface plasmon sensor
  • propagating surface plasmon
  • localized surface plasmon
  • metal grating
  • substrate of the localized surface plasmon
  • refractive index
  • sensitivity
  • chemosensor
  • figure of merit
  • nanostructures
  • nanomaterials
  • surface-enhanced Raman scattering

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Published Papers (4 papers)

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Research

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7 pages, 1466 KiB  
Communication
Enhancing the Spectral Sensitivity of Prism-Based SPR Sensors: The Role of Analyte RI
by Wenyuan Wang, Tianfa Liao, Hongxiang Lin, Han Cui and Xiaohui Wei
Chemosensors 2024, 12(11), 242; https://doi.org/10.3390/chemosensors12110242 - 20 Nov 2024
Viewed by 246
Abstract
A theoretical approach is presented to significantly enhance the spectral sensitivity of prism-based SPR sensors. The spectral sensitivity of prism-based SPR sensors is derived based on the coupling conditions of SPR and might exceed 105 nm/RIU for analytes with large RI values [...] Read more.
A theoretical approach is presented to significantly enhance the spectral sensitivity of prism-based SPR sensors. The spectral sensitivity of prism-based SPR sensors is derived based on the coupling conditions of SPR and might exceed 105 nm/RIU for analytes with large RI values when other sensor parameters are carefully considered, including the RI of the prism, the angle of incidence, and the SPR active material. The spectral sensitivity could be markedly enhanced, reaching up to 10,000 nm/RIU by fine-tuning the effective RI of the incident light to be slightly larger, specifically 0.01~0.02 RIU, than the RI of the analyte, which is attributed to the large dielectric permittivity of the SPR active material, the key factor for achieving high sensitivity. The dynamic range is 0.040 RIU in the case of high sensitivity, which is sufficient in most applications. Moreover, the spectral sensitivity could be pushed even higher, into the range of 106~108 nm/RIU, by positioning the effective RI of the incident light closer to that of the analyte. However, it requires a careful balance between optimizing the sensitivity and maintaining an acceptable dynamic range. Full article
(This article belongs to the Special Issue Advanced Surface Plasmon Resonance Sensors)
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13 pages, 2739 KiB  
Article
AuNPs/Ti3C2 Signal-Enhanced Surface Plasmon Resonance Imaging Biosensor for Ultrasensitive Detection of miRNA
by Yirui Qin, Li Jiang, Rengang Sun, Yunzhu Fang, Boya Shi and Shangzhong Jin
Chemosensors 2024, 12(4), 66; https://doi.org/10.3390/chemosensors12040066 - 17 Apr 2024
Viewed by 1319
Abstract
MicroRNA-21 is a potential cancer biomarker that is highly expressed in many cancer cells. Therefore, it is important to perform highly sensitive detection of miRNA-21. In this study, we designed a surface plasmon resonance imaging (SPRi) sensor based on an AuNPs/Ti3C [...] Read more.
MicroRNA-21 is a potential cancer biomarker that is highly expressed in many cancer cells. Therefore, it is important to perform highly sensitive detection of miRNA-21. In this study, we designed a surface plasmon resonance imaging (SPRi) sensor based on an AuNPs/Ti3C2 composite for real-time and highly sensitive detection of miRNA-21. The fixation of the capture polyA-DNA probes was completed by the freezing method, which improved the detection efficiency. DNA−AuNPs/Ti3C2 conjugates were added to amplify the SPRi signal. The signal amplification combines the large specific surface area of Ti3C2 and the electronic coupling between the local surface plasmon resonance (LSPR) of AuNPs and the plasmon wave on the surface of the Au chip, thereby enhancing the SPRi response signal. Using this sensing strategy, the detection limit for miRNA-21 can reach 6.13 fM, with a wide dynamic range between 10 fM and 10 nM. In addition, the sensor has excellent selectivity for miRNA-21 and miRNAs with similar sequences, and receives minimal interference when applied to complex matrices. Based on these results, we believe that this study provides a simple and highly sensitive method for miRNA detection, which has great potential for the quantitative detection of miRNA in biomedical research and early clinical diagnosis. Full article
(This article belongs to the Special Issue Advanced Surface Plasmon Resonance Sensors)
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15 pages, 2885 KiB  
Article
Application of SPR Method as an Approach to Gas Phase Sensing of Volatile Compound Profile in Mezcal Spirits Conferred by Agave Species
by Araceli Sánchez-Álvarez, Donato Luna-Moreno, Oscar Silva-Hernández and Melissa Marlene Rodríguez-Delgado
Chemosensors 2023, 11(1), 70; https://doi.org/10.3390/chemosensors11010070 - 15 Jan 2023
Cited by 2 | Viewed by 1742
Abstract
Mezcal is a traditional Mexican spirit produced by distilling fermented agave, with a unique taste directly related to its volatile compound composition. Thus, the present research proposed the surface plasmon resonance (SPR) technique as a potential method to differentiate mezcals, studying several parameters [...] Read more.
Mezcal is a traditional Mexican spirit produced by distilling fermented agave, with a unique taste directly related to its volatile compound composition. Thus, the present research proposed the surface plasmon resonance (SPR) technique as a potential method to differentiate mezcals, studying several parameters at angular interrogations and at a fixed angle. The study evaluated eight mezcals from different agave species using SPR and gas chromatography-mass spectrometry (GC-MS). Despite the similarities in mezcal spirits corresponding to the same ethanol content and the same artisanal method, it was possible to obtain well-differentiated characteristics by SPR parameters, such as the width of the curve, the resonant angle, and reflectance intensities. Therefore, it was possible to demonstrate the potential use of the SPR technique as a rapid first approach to a screening test to differentiate types of spirits. Full article
(This article belongs to the Special Issue Advanced Surface Plasmon Resonance Sensors)
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Review

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24 pages, 5419 KiB  
Review
Detection of Kidney Complications Relevant Concentrations of Ammonia Gas Using Plasmonic Biosensors: A Review
by Fahad Usman, Kamarul Hawari Ghazali, Razali Muda, John Ojur Dennis, Khalid Hassan Ibnaouf, Osamah A. Aldaghri, Ahmed Alsadig, Nasrul Hadi Johari and Rajan Jose
Chemosensors 2023, 11(2), 119; https://doi.org/10.3390/chemosensors11020119 - 6 Feb 2023
Cited by 8 | Viewed by 2347
Abstract
Kidney-related health problems cause millions of deaths around the world annually. Fortunately, most kidney problems are curable if detected at the earliest stage. Continuous monitoring of ammonia from exhaled breath is considered as a replacement for the conventional blood-based monitoring of chronic kidney [...] Read more.
Kidney-related health problems cause millions of deaths around the world annually. Fortunately, most kidney problems are curable if detected at the earliest stage. Continuous monitoring of ammonia from exhaled breath is considered as a replacement for the conventional blood-based monitoring of chronic kidney disease (CKD) and kidney failure owing to its cost effectiveness, non-invasiveness, excellent sensitivity, and capabilities for real-time measurement. The detection of ammonia for renal failure requires a biosensor with a detection limit of 1000 ppb (1 ppm). Among biosensors, plasmonic biosensors have attracted considerable research interest due to their potential for ultra-sensitivity, single particle/molecular level detection capability, multiplexing capability, photostability, real-time measurement, label-free measurement, room temperature operation, naked-eye readability, ease of miniaturization via simple sensor chip fabrication, and instrumentation, among other features. In this review, plasmonic sensors for the detection of ammonia gas relevant to kidney problems (LOD ≤ 1 ppm) are reviewed. In addition, the utilized strategies and surface functionalization for the plasmonic sensor are highlighted. Moreover, the main limitations of the reported sensors are stated for the benefit of future researchers. Finally, the challenges and prospects of plasmonic-based ammonia gas biosensors for potential application in the monitoring and screening of renal (kidney) failure, as well as the endpoint of the dialysis session, are stated. Full article
(This article belongs to the Special Issue Advanced Surface Plasmon Resonance Sensors)
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