Sensors for Food Testing, Environmental Analysis, and Medical Diagnostics

A special issue of Chemosensors (ISSN 2227-9040). This special issue belongs to the section "Applied Chemical Sensors".

Deadline for manuscript submissions: 30 April 2025 | Viewed by 1582

Special Issue Editors


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International Centre of Biodynamics, 1B Intrarea Portocalelor, 060101 Bucharest, Romania
Interests: analytical chemistry; biosensors; electrochemical sensors; aptamers; wine
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1. Faculty of Medicine, Transilvania University of Brasov, 500019 Brașov, Romania
2. Research Center for Fundamental Research and Prevention Strategies in Medicine, Research and Development Institute of Transilvania University of Brasov, 500484 Brașov, Romania
Interests: (bio)analytical methods; biochemistry, electrochemical (bio)sensors; studies of the activity of bioactive compounds in cell cultures; (tele)monitoring-(tele)diagnosis in life sciences
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BAE-LBBM-USR CNRS 3579, Université de Perpignan Via Domitia, 52 Avenue Paul Allude, 66860 Perpignan, CEDEX, France
Interests: electrochemical and optical biosensors; aptasensors for food and environmental control
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

With technological advancements, sensors have become indispensable tools in various industries, enabling us to monitor, analyse, and diagnose with unprecedented precision and efficiency. This Special Issue showcases the latest research and developments in sensor technology and its applications in food testing, environmental analyses, and medical diagnostics.

Food Testing with Sensors

In the food industry, sensors play crucial roles in ensuring product safety, quality, and authenticity. Sensors can be used to detect contaminants, allergens, pathogens, and other potential hazards, as well as to monitor freshness, ripeness, and nutritional value. Advances in (bio)sensor technology, nanomaterials, and smart sensors have enabled faster and more reliable food testing, enabling real-time monitoring and early warning systems.

Environmental Analyses with Sensors

Environmental sensors are indispensable in monitoring air, water, and soil quality. They can detect pollutants, toxins, greenhouse gases, and other harmful substances, providing important data for environmental protection and risk assessment.

Medical Diagnostics with Sensors

In the field of medical diagnostics, sensors are used to detect biological active compounds, disease biomarkers, and other biological indicators, as do modern healthcare devices. Biosensors, electrochemical sensors, and optical sensors are some of the most commonly used technologies for rapid, point-of-care testing. These sensors can be integrated into wearable devices, smartphones, and other portable platforms, making diagnostic testing more accessible and convenient for patients.

We invite researchers, engineers, and practitioners from these fields to contribute their work and share their insights.

Dr. Alina Vasilescu
Prof. Dr. Mihaela Badea
Prof. Dr. Jean Louis Marty
Guest Editors

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Keywords

  • sensor technology
  • food safety
  • environmental monitoring
  • medical diagnostics
  • biosensors
  • nanomaterials
  • Smart sensors
  • point-of-care testing
  • real-time monitoring

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Published Papers (2 papers)

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Research

11 pages, 702 KiB  
Article
Stretching the Limits of Refractometric Sensing in Water Using Whispering-Gallery-Mode Resonators
by Kevin Soler-Carracedo, Antonia Ruiz, Susana Ríos, Sergio de Armas-Rillo, Leopoldo L. Martín, Martin Hohmann, Inocencio R. Martín and Fernando Lahoz
Chemosensors 2025, 13(2), 33; https://doi.org/10.3390/chemosensors13020033 - 24 Jan 2025
Viewed by 421
Abstract
A novel application of microresonators for refractometric sensing in aqueous media is presented. To carry out this approach, microspheres of different materials and sizes were fabricated and doped with Nd3+ ions. Under 532 nm excitation, the microspheres presented typical NIR Nd3+ [...] Read more.
A novel application of microresonators for refractometric sensing in aqueous media is presented. To carry out this approach, microspheres of different materials and sizes were fabricated and doped with Nd3+ ions. Under 532 nm excitation, the microspheres presented typical NIR Nd3+ emission bands with superimposed sharp peaks, related to the Whispering Gallery Modes (WGMs), due to the geometry of the microspheres. When the microspheres were submerged in water with increasing concentrations of glycerol, spectral shifts for the WGMs were observed as a function of the glycerol concentration. These spectral shifts were studied and calibrated for three different microspheres and validated with the theoretical shifts, obtained by solving the Helmholtz equations for the electromagnetic field, considering the geometry of the system, and also by calculating the extinction cross-section. WGM shifts strongly depend on the diameter of the microspheres and their refractive index (RI) difference compared with the external medium, and are greater for decreasing values of the diameter and lower values of RI difference. Experimental sensitivities ranging from 2.18 to 113.36 nm/RIU (refractive index unit) were obtained for different microspheres. Furthermore, reproducibility measurements were carried out, leading to a repeatability of 2.3 pm and a limit of detection of 5 × 10−4 RIU. The proposed sensors, taking advantage of confocal microscopy for excitation and detection, offer a robust, reliable, and contactless alternative for environmental water analysis. Full article
16 pages, 1090 KiB  
Article
Effectiveness of an E-Nose Based on Metal Oxide Semiconductor Sensors for Coffee Quality Assessment
by Yhan S. Mutz, Samara Mafra Maroum, Leticia L. G. Tessaro, Natália de Oliveira Souza, Mikaela Martins de Bem, Loyane Silvestre Alves, Luisa Pereira Figueiredo, Denes K. A. do Rosario, Patricia C. Bernardes and Cleiton Antônio Nunes
Chemosensors 2025, 13(1), 23; https://doi.org/10.3390/chemosensors13010023 - 18 Jan 2025
Viewed by 599
Abstract
Coffee quality, which ultimately is reflected in the beverage aroma, relies on several aspects requiring multiple approaches to check it, which can be expensive and/or time-consuming. Therefore, this study aimed to develop and calibrate an electronic nose (e-nose) coupled with chemometrics to approach [...] Read more.
Coffee quality, which ultimately is reflected in the beverage aroma, relies on several aspects requiring multiple approaches to check it, which can be expensive and/or time-consuming. Therefore, this study aimed to develop and calibrate an electronic nose (e-nose) coupled with chemometrics to approach coffee-related quality tasks. Twelve different metal oxide sensors were employed in the e-nose construction. The tasks were (i) the separation of Coffea arabica and Coffea canephora species, (ii) the distinction between roasting profiles (light, medium, and dark), and (iii) the separation of expired and non-expired coffees. Exploratory analysis with principal component analysis (PCA) pointed to a fair grouping of the tested samples according to their specification, indicating the potential of the volatiles in grouping the samples. Moreover, a supervised classification employing soft independent modeling of class analogies (SIMCA), partial least squares discriminant analysis (PLS-DA), and least squares support vector machine (LS-SVM) led to great results with accuracy above 90% for every task. The performance of each model varies with the specific task, except for the LS-SVM models, which presented a perfect classification for all tasks. Therefore, combining the e-nose with distinct classification models could be used for multiple-purpose classification tasks for producers as a low-cost, rapid, and effective alternative for quality assurance. Full article
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Planned Papers

The below list represents only planned manuscripts. Some of these manuscripts have not been received by the Editorial Office yet. Papers submitted to MDPI journals are subject to peer-review.

Title: Efficient peroxide nanosensors via optical fluorescence and second harmonic generation conversions (SHG)
Authors: Nader Shehata; Sara Noman; Effat Samir; Mohamed Salah; Remya Nair; Ali Hajjiah; Ishac Kandas
Affiliation: 1 Center of Smart Nanotechnology and Photonics (CSNP), Smart CI Research Center, Alexandria University, Alexandria 21544 Egypt; 2 Department of Engineering Mathematics and Physics, Faculty of Engineering, Alexandria University, Alexandria 21544 Egypt; 3 Kuwait College of Science and Technology, Doha Area, 7th Ring Road, Safat 13133, Kuwait; 4 USTAR Bio-innovation center, Utah State University, Logan, Utah 84341 United States. 5 Physics department, Faculty of Science, Mansoura University, Mansoura, 35516, Egypt 6 Department of Electrical Engineering, Old Dominion University, Virginia, United States; 7 Faculty of Engineering and Petroleum, Kuwait University, Khaldiya, 13133, Kuwait;
Abstract: The scope of using cerium oxide -gold nanoparticles (CeO2 - Au NPs) as an optical sensor is studied via fluorescence quenching technique. Under violet excitation, ceria NPs have a strong emission in the visible region (~ 530 nm) which clearly proves its strong fluorescence behavior. Here, Au NPs are embedded in-situ with CeO2 NPs. Afterwards, the system is applied in the field of peroxide sensing in aqueous media. The fluorescence intensity is found to be affected by the addition of peroxides into CeO2 - Au NPs. The sensitivity of ceria NPs in peroxide quencher detection is found to be enhanced considerably by the addition of Au NPs. This is because of the plasmonic resonance of Au NPs as it is optically coupled with the fluorescence emission spectrum of ceria. The bandgap of ceria is also found to be decreased by the addition of Au NPs which is due to the creation of more oxygen vacancies inside the non-stoichiometric crystalline structure of ceria. The sensitivity of optical sensing material, ceria–gold NPs with added peroxide is characterized by Stern-Volmer constant and is found to be 0.17627 M−1 which is higher than the case of using ceria NPs only. Ceria–gold NPs with enhanced optical sensitivity can be employed as an optical sensing host for peroxides which plays a major role in many important applications such as biomedicine and water quality monitoring.

Title: Mullite 3D Printed Structures for Humidity Detection
Authors: Y. Milovanov; A. Bertero; B. Coppola,; P. Palmero; J.M. Tulliani
Affiliation: Politecnico di Torino, Department of Applied Science and Technology, INSTM R.U PoliTO-LINCE Laboratory, Corso Duca degli Abruzzi 24, 10129 Turin, Italy
Abstract: Three-dimensional-printed complex mullite structures based on triply periodic minimal surfaces (TPMS), namely, the Schwartz and Gyroid with 2 different thicknesses (Schwartz 1 and Gyroid 1 – 4 mm, Schwartz 2 and Gyroid 2 – 6mm) were fabricated and tested as humidity sensors. The samples were sintered at 1450 °C and tested in the range from 0% to 85% relative humidity (RH) at room temperature to evaluate the effect of geometry and thickness on humidity sensitivity. When exposed to water vapor at room temperature, the impedance value decreased from 75 MΩ under dry air to 31 MΩ under 85 RH% for Schwartz 1 structure (from 133 MΩ to 97 MΩ for Schwartz 2 structure) and from 96 MΩ under dry air to 79 MΩ for Gyroid 1 structure (from 100 MΩ to 14 MΩ for Gyroid 2 structure). The results showed that at 85% RH, the best sensitivity of sensors was achieved for Gyroid 2 structure. Sensors exhibit a good repeatability. There was no interference in the presence of other gases.

Title: Xerogel carbon porous based in lignonocellocic precorsor for nanomolar detection of Taxifolin in peanuts foods
Authors: A. J. Varela Barrios; R. Coneo Rodriguez; R. D. Alaniz; G. Planes; G. D. Pierini*; A. M. Granero*
Affiliation: a Grupo de Electroanalítica (GEANA), Departamento de Química, Instituto para el Desarrollo Agroindustrial y de la Salud (IDAS), Facultad de Ciencias Exactas, Físico-Químicas y Naturales, Universidad Nacional de Río Cuarto, Agencia Postal No 3, 5800, Río Cuarto, Argentina. b Departamento de Química, Instituto de Investigaciones en Tecnologías Energéticas y Materiales Avanzados (IITEMA), Universidad Nacional de Río Cuarto, Agencia Postal No 3, 5800, Río Cuarto, Argentina.
Abstract: Xerogel carbon porous based in lignonocellocic obtained from municipal waste was used to construct a sensor to determine Taxifolin (Tx). The developed sensor is based on using a xerogel carbon porous dispersion to modify glassy carbon electrodes. Tx exhibits an oxidation peak at 0.61 V (vs. Ag/AgClKCl) in 1 M H2SO4 on the CV electrode modified with the porous material, the participation of protons in the oxidation mechanism was confirmed and an adsorptive control on the modified electrode was observed. As analytical parameters of the developed sensor, a detection limit of 0.5 nM, a linear range between 1 and 100 nM, with a repeatability

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