Crosstalk between Circadian Rhythm and Diseases 2.0
A special issue of Clocks & Sleep (ISSN 2624-5175). This special issue belongs to the section "Disorders".
Deadline for manuscript submissions: closed (30 November 2021) | Viewed by 251
Special Issue Editor
Interests: crosstalk between circadian rhythm and tumor progression; pathological analysis in human and mouse tissues; functional analysis of DEC1 and DEC2 in tumor progression; molecular pathways of DEC1 and DEC2; crosstalk between basic and clinical research, involving clock genes
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Circadian rhythm is dominantly regulated by clock genes. Recent evidence suggests that the clock genes CLOCK, BMAL1/2, DEC1/2, PER1/2/3, and CRY1/2 play important roles in tumor progression, metabolism, immune responses, and sleep disorders by regulating apoptosis-related factors, cell cycle regulators, and inflammatory factors. On the other hand, various kinds of stress, such as hypoxia, inflammation, and anti-tumor drugs, affect the expression of clock genes. Therefore, clock genes have multiple functions in vivo that are associated with various kinds of diseases. Our aim is to improve the understanding of crosstalk between circadian rhythms, clock genes, and diseases to allow the development of strategies to overcome diseases, involving clock gene abnormalities. We encourage the submission of original articles and reviews involving circadian rhythm/clock genes and diseases.
Topics include, but are not limited to the following:
- Relevant circadian rhythm/clock genes and diseases
- Molecular pathways of clock genes, involving tumor progression, metabolism, inflammation, etc.
- Functional analyses of clock genes in mouse models
You may choose our Joint Special Issue in International Journal of Molecular Sciences.
Dr. Fuyuki Sato
Guest Editor
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Keywords
- circadian rhythm
- clock genes
- tumor progression
- metabolism
- immune response
- inflammation
- molecular pathway
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