New Perspectives in Pharmaceutical Crystallization and Possibilities of Analysis of the Obtained Crystals
A special issue of Crystals (ISSN 2073-4352). This special issue belongs to the section "Biomolecular Crystals".
Deadline for manuscript submissions: closed (30 October 2023) | Viewed by 248
Special Issue Editors
Interests: crystallography; biocrystals; crystal growth; pharmaceutical physics; biophysics; crystal chemistry; crystal physics; biomineralization condensed matter; ADME-TOX analysis; biological macromolecules; X-ray analysis; electron diffraction analysis; neutron diffraction analysis
2. Research Center for Pharmaco-Toxicological Evaluations, Faculty of Pharmacy, Victor Babes University of Medicine and Pharmacy, 2 Eftimie Murgu Street, 300041 Timisoara, Romania
Interests: drug analysis; drug product design and development; analytical technique; magnetic and metallic nanoparticles; polymeric nanoparticles; solid–lipid nanoparticles; drug–cyclodextrin inclusion; complexation; cell biology; biological active compounds; biomedical microbiology; biophysics; biochemistry
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Special Issue Information
Dear Colleagues,
Pharmaceutical crystallization processes can be developed to explore continuous manufacturing in the pharmaceutical industry and are one of many methods to obtain and analyse the physical and chemical properties of crystals. Pharmaceutical crystallization is an important technology within pharmaceutical processes and can be used to determine numerous product properties in the solid‒liquid separation process, which is not only a separation and purification process but also a refining process.
By using pharmaceutical crystallization processes, we can obtain co-crystals too, which are crystalline complexes of active/neutral compounds. Co-crystallization determine the preservation of the intrinsic pharmacological properties of the active ingredients such as the melting point, solubility, and dissolution. Drug‒drug co-crystals represent a promising line of research in given that combined therapies are frequently prescribed for the effective treatment of numerous pathologies, meaning the co-crystals of multiple active compounds might overcome the drawbacks of conventionally combined drugs.
Dr. Mirela Nicolov
Prof. Dr. Codruta Soica
Guest Editors
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Keywords
- crystallography
- biocrystals
- crystal growth
- pharmaceutical physics
- crystal chemistry
- crystal physics
- biomineralization condensed matter
- ADME-TOX analysis
- biological macromolecules
- X-ray
- electron diffraction
- neutron diffraction
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